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The map label for this gene is ELP3 [C]

Identifier: 20094488

GI number: 20094488

Start: 1018718

End: 1020367

Strand: Reverse

Name: ELP3 [C]

Synonym: MK1052

Alternate gene names: 20094488

Gene position: 1020367-1018718 (Counterclockwise)

Preceding gene: 20094490

Following gene: 20094482

Centisome position: 60.2

GC content: 62.48

Gene sequence:

>1650_bases
ATGTGTTGCGCCCCCACGGTACCGGAGAACCGTACGGGGGTGAGAGATGTGTCCGAGGCCGACGCCTTCGACATGGCGTG
CCGCGAACTCGTGGAGAAGATGCTGTCGGGTGAGATCCGAACTAAAGGCGAGCTACAGGAGGCCAAGCGCGAGGTCTGCA
GGAAATACGGTCTTTCGAAGTTCCCCACGGACGCGGACGTCCTGGAACGCGCAACCCCGGAGGAGCGCGAGAAACTCCGA
GAGATCGTCGTGAAGAAACCCGTCCGATCGATCTCGGGCGTGGCCGTCGTCGCGGTGATGACGAAGCCCTATCCGTGTCC
ACATGGCCGTTGTGCGTACTGCCCGGGTGGTCCCGAGAAGGGCGTACCACAGAGCTACACGGGTAAGGAGCCGGCCGGCC
GTCGGGCTAAGGAGCACGAGTTCCACCCACGGAAGCAGGTCGAGGCGCGCATACGGCAGCTGGAGATCTCGGGTCACCCC
ACCGACAAGATCGAGCTGATCGTGATGGGGGGTACGTTCCCCGCGACACCGTTGTGTTACCAGGAGTGGTTCGTGCGGGA
GTGTCTGAACGCGATGACCGGGAAGGACGCGCTCACGATCGAGGAGGCGCAGAAGTACGCGGAAACTTCGGAACGCCGAC
CCGTGGGAATCACCTTCGAAACGCGGCCCGACTACTGCAAGGAGGAGCATGTGGACCACATGCTCAAGCTGGGCGCCACC
AGGGTTGAAGTGGGAGTCCAGACGATCTACGACTTCATACTGAAGCGCGTGGACCGCGGTCACACCGTGAAGGATACCGT
CGAGGCGACACGTATCCTCAAGGACGCCGGTCTGAAAGTGTGTTACCACATCATGCCCGGTCTCCCGGGCTCGAACCCCG
AACGCGACCTCAGGATGTTAAAGCGACTGTTCAAGGACCCGCGGTTCAAGCCGGATATGCTGAAGATCTACCCGTGTATG
GTCTTCGAGGATACGCCCCTATACGACGCGTGGAAACGTGGCGAGTACGAGCCATACGACGAGGAAACCGCGGTGAAAGT
CATCGCCGAGGCGAAACACCGCTACGTACCGGAGTACTGCCGCATCATGCGGGTTCAGCGGGACATCCCGGCCCACTTGG
CCGCCGCCGGCATCCGGAAGACGAACCTACGCCAGCTCGTCCACGATTACCTGGAGGAGAAAGGCTGGGAGTGTCGGTGT
ATCCGCTGTCGGGAGGCGGGTCACAGGATGCGCCAAGGTGTTGAGGTGGATCCGGGGCGAGCCGAGCTCAGGATCATCAA
AGAGCGTACGTGGAAGGGGGGCATGGACTACTTCCTGGCGTACGAGGATCCGGAGGCGGACGCTATACTCGGTTATCTGA
GGCTCAGGAAGCCCACGGAGCTGGCCCACAGACCGGAGATCGATCCCGAGACGGCCATCGTGCGCGAGCTGAAGGTCGTC
GGACCGACGGTGCCGATCGGCGAGCGGGACACGGACGCCGTCCAACATCGGGGCCTCGGCGAGCGGCTGATGAGGAAGGC
GGAGGAGCTCGCCGCCAGCGAGCTGGATGCGGACAAGATCATCGTGATCAGTGCCATCGGGACGCGCGAGTACTACCGGA
AGCTCGGGTACGAGCGCGTCGGCCCGTACATGGGTAAGGATTTAACGTGA

Upstream 100 bases:

>100_bases
CGGCGCTCTAACCAGGCTGAGCTACCGCGGCGATCCCCACAAACGCCGGATTTCACCAGTTCCATCCGGCGCCAGCTGTA
CCCTCCCGACGATCGATTAA

Downstream 100 bases:

>100_bases
AGGCACCAGAACCACGGGAACGTCCCTCACGTGCCCCTCGATCCCCCGTCGGAACGTTATATCCTCGAACCTGGGGATGT
GACCCACGCCTACCACCACG

Product: RNA polymerase II complex ELP3 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MCCAPTVPENRTGVRDVSEADAFDMACRELVEKMLSGEIRTKGELQEAKREVCRKYGLSKFPTDADVLERATPEEREKLR
EIVVKKPVRSISGVAVVAVMTKPYPCPHGRCAYCPGGPEKGVPQSYTGKEPAGRRAKEHEFHPRKQVEARIRQLEISGHP
TDKIELIVMGGTFPATPLCYQEWFVRECLNAMTGKDALTIEEAQKYAETSERRPVGITFETRPDYCKEEHVDHMLKLGAT
RVEVGVQTIYDFILKRVDRGHTVKDTVEATRILKDAGLKVCYHIMPGLPGSNPERDLRMLKRLFKDPRFKPDMLKIYPCM
VFEDTPLYDAWKRGEYEPYDEETAVKVIAEAKHRYVPEYCRIMRVQRDIPAHLAAAGIRKTNLRQLVHDYLEEKGWECRC
IRCREAGHRMRQGVEVDPGRAELRIIKERTWKGGMDYFLAYEDPEADAILGYLRLRKPTELAHRPEIDPETAIVRELKVV
GPTVPIGERDTDAVQHRGLGERLMRKAEELAASELDADKIIVISAIGTREYYRKLGYERVGPYMGKDLT

Sequences:

>Translated_549_residues
MCCAPTVPENRTGVRDVSEADAFDMACRELVEKMLSGEIRTKGELQEAKREVCRKYGLSKFPTDADVLERATPEEREKLR
EIVVKKPVRSISGVAVVAVMTKPYPCPHGRCAYCPGGPEKGVPQSYTGKEPAGRRAKEHEFHPRKQVEARIRQLEISGHP
TDKIELIVMGGTFPATPLCYQEWFVRECLNAMTGKDALTIEEAQKYAETSERRPVGITFETRPDYCKEEHVDHMLKLGAT
RVEVGVQTIYDFILKRVDRGHTVKDTVEATRILKDAGLKVCYHIMPGLPGSNPERDLRMLKRLFKDPRFKPDMLKIYPCM
VFEDTPLYDAWKRGEYEPYDEETAVKVIAEAKHRYVPEYCRIMRVQRDIPAHLAAAGIRKTNLRQLVHDYLEEKGWECRC
IRCREAGHRMRQGVEVDPGRAELRIIKERTWKGGMDYFLAYEDPEADAILGYLRLRKPTELAHRPEIDPETAIVRELKVV
GPTVPIGERDTDAVQHRGLGERLMRKAEELAASELDADKIIVISAIGTREYYRKLGYERVGPYMGKDLT
>Mature_549_residues
MCCAPTVPENRTGVRDVSEADAFDMACRELVEKMLSGEIRTKGELQEAKREVCRKYGLSKFPTDADVLERATPEEREKLR
EIVVKKPVRSISGVAVVAVMTKPYPCPHGRCAYCPGGPEKGVPQSYTGKEPAGRRAKEHEFHPRKQVEARIRQLEISGHP
TDKIELIVMGGTFPATPLCYQEWFVRECLNAMTGKDALTIEEAQKYAETSERRPVGITFETRPDYCKEEHVDHMLKLGAT
RVEVGVQTIYDFILKRVDRGHTVKDTVEATRILKDAGLKVCYHIMPGLPGSNPERDLRMLKRLFKDPRFKPDMLKIYPCM
VFEDTPLYDAWKRGEYEPYDEETAVKVIAEAKHRYVPEYCRIMRVQRDIPAHLAAAGIRKTNLRQLVHDYLEEKGWECRC
IRCREAGHRMRQGVEVDPGRAELRIIKERTWKGGMDYFLAYEDPEADAILGYLRLRKPTELAHRPEIDPETAIVRELKVV
GPTVPIGERDTDAVQHRGLGERLMRKAEELAASELDADKIIVISAIGTREYYRKLGYERVGPYMGKDLT

Specific function: Unknown

COG id: COG1243

COG function: function code KB; Histone acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI23510283, Length=547, Percent_Identity=41.6819012797075, Blast_Score=414, Evalue=1e-115,
Organism=Escherichia coli, GI2367204, Length=159, Percent_Identity=28.3018867924528, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI133955098, Length=530, Percent_Identity=43.2075471698113, Blast_Score=416, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6325171, Length=528, Percent_Identity=42.4242424242424, Blast_Score=402, Evalue=1e-113,
Organism=Drosophila melanogaster, GI19920684, Length=529, Percent_Identity=41.5879017013232, Blast_Score=404, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR006638
- InterPro:   IPR005910
- InterPro:   IPR007197 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 62746; Mature: 62746

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCCAPTVPENRTGVRDVSEADAFDMACRELVEKMLSGEIRTKGELQEAKREVCRKYGLSK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
FPTDADVLERATPEEREKLREIVVKKPVRSISGVAVVAVMTKPYPCPHGRCAYCPGGPEK
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEECCCCCCCC
GVPQSYTGKEPAGRRAKEHEFHPRKQVEARIRQLEISGHPTDKIELIVMGGTFPATPLCY
CCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHH
QEWFVRECLNAMTGKDALTIEEAQKYAETSERRPVGITFETRPDYCKEEHVDHMLKLGAT
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCH
RVEVGVQTIYDFILKRVDRGHTVKDTVEATRILKDAGLKVCYHIMPGLPGSNPERDLRML
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KRLFKDPRFKPDMLKIYPCMVFEDTPLYDAWKRGEYEPYDEETAVKVIAEAKHRYVPEYC
HHHHHCCCCCCCHHEEEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHH
RIMRVQRDIPAHLAAAGIRKTNLRQLVHDYLEEKGWECRCIRCREAGHRMRQGVEVDPGR
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCCH
AELRIIKERTWKGGMDYFLAYEDPEADAILGYLRLRKPTELAHRPEIDPETAIVRELKVV
HHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHH
GPTVPIGERDTDAVQHRGLGERLMRKAEELAASELDADKIIVISAIGTREYYRKLGYERV
CCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHH
GPYMGKDLT
CCCCCCCCC
>Mature Secondary Structure
MCCAPTVPENRTGVRDVSEADAFDMACRELVEKMLSGEIRTKGELQEAKREVCRKYGLSK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
FPTDADVLERATPEEREKLREIVVKKPVRSISGVAVVAVMTKPYPCPHGRCAYCPGGPEK
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEECCCCCCCC
GVPQSYTGKEPAGRRAKEHEFHPRKQVEARIRQLEISGHPTDKIELIVMGGTFPATPLCY
CCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHH
QEWFVRECLNAMTGKDALTIEEAQKYAETSERRPVGITFETRPDYCKEEHVDHMLKLGAT
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCH
RVEVGVQTIYDFILKRVDRGHTVKDTVEATRILKDAGLKVCYHIMPGLPGSNPERDLRML
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KRLFKDPRFKPDMLKIYPCMVFEDTPLYDAWKRGEYEPYDEETAVKVIAEAKHRYVPEYC
HHHHHCCCCCCCHHEEEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHH
RIMRVQRDIPAHLAAAGIRKTNLRQLVHDYLEEKGWECRCIRCREAGHRMRQGVEVDPGR
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCCH
AELRIIKERTWKGGMDYFLAYEDPEADAILGYLRLRKPTELAHRPEIDPETAIVRELKVV
HHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHH
GPTVPIGERDTDAVQHRGLGERLMRKAEELAASELDADKIIVISAIGTREYYRKLGYERV
CCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHH
GPYMGKDLT
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]