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The map label for this gene is SEC59

Identifier: 20094414

GI number: 20094414

Start: 939220

End: 939801

Strand: Direct

Name: SEC59

Synonym: MK0978

Alternate gene names: NA

Gene position: 939220-939801 (Clockwise)

Preceding gene: 20094413

Following gene: 20094415

Centisome position: 55.41

GC content: 58.93

Gene sequence:

>582_bases
TTGACTAGCAAGGAGTTGGGTCGCCAGCTTATCCACGCTACGTTCGGTCTCCTGTTCCTCCTCCCTCTTCACATGCTCGG
AGTGTACGAGTTCGCCTTACTACTACTCTCAGGTCTCATCGCTGGTGTATCCGTATCTTTCGCGTTAAGGCGCGGCCTTC
ACGTTCCCATAGCGAAAGAACTCGTAGACGCCTTCGAACGGCCCGACGAGATGCACATACCCGGTCAAGGAACGCTCCAC
TTTGTGACGGGTCTCCTCCTGGCGACCATCATCTGCCCCTACACGAAGGTCCTCGACGTTACGATCATCGTCTTATCCGT
CGGAGACAGTGCCTCCACGATCGCGGGTAAAGCCATCGGGCGTATCCCTATACCCTACAGCTCCAGGAAGACCGTGGAGG
GCAGCCTCGTGGGCTTCACCGCCGCCGCCCTAGCCTCACTGGCTTGGACTGGGGATGTGGTGGTTTCGGCTCTAGCGGCG
GGGGTCGGAATGCTCGTCGAAAGCTTGCCCACGCCAAACGACAACGTGACGATACCGGTGGCCGTCTCTGTGGCGCTAGG
CTTCTGGTGGGGACTACTGTAG

Upstream 100 bases:

>100_bases
GCGGAGGCCATAGAACAAGCCATCGACTGGAAGGTCCCGAAAATCAGGATGATGGATGGAAGGGGGGCCGAGCGCGCTGC
GCGCATCGTCGCAGGAACGC

Downstream 100 bases:

>100_bases
ATTGCGCTGGAACCTGACGGTAGGGGTCACCGCCCTGGCCCTTATTCTCCTCGTCACCGCGCTGGCACCGTCCTACATTC
CGGCCGCGTGCCTACTGCTG

Product: dolichol kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTSKELGRQLIHATFGLLFLLPLHMLGVYEFALLLLSGLIAGVSVSFALRRGLHVPIAKELVDAFERPDEMHIPGQGTLH
FVTGLLLATIICPYTKVLDVTIIVLSVGDSASTIAGKAIGRIPIPYSSRKTVEGSLVGFTAAALASLAWTGDVVVSALAA
GVGMLVESLPTPNDNVTIPVAVSVALGFWWGLL

Sequences:

>Translated_193_residues
MTSKELGRQLIHATFGLLFLLPLHMLGVYEFALLLLSGLIAGVSVSFALRRGLHVPIAKELVDAFERPDEMHIPGQGTLH
FVTGLLLATIICPYTKVLDVTIIVLSVGDSASTIAGKAIGRIPIPYSSRKTVEGSLVGFTAAALASLAWTGDVVVSALAA
GVGMLVESLPTPNDNVTIPVAVSVALGFWWGLL
>Mature_192_residues
TSKELGRQLIHATFGLLFLLPLHMLGVYEFALLLLSGLIAGVSVSFALRRGLHVPIAKELVDAFERPDEMHIPGQGTLHF
VTGLLLATIICPYTKVLDVTIIVLSVGDSASTIAGKAIGRIPIPYSSRKTVEGSLVGFTAAALASLAWTGDVVVSALAAG
VGMLVESLPTPNDNVTIPVAVSVALGFWWGLL

Specific function: Unknown

COG id: COG0170

COG function: function code I; Dolichol kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: NA

Molecular weight: Translated: 20285; Mature: 20154

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKELGRQLIHATFGLLFLLPLHMLGVYEFALLLLSGLIAGVSVSFALRRGLHVPIAKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LVDAFERPDEMHIPGQGTLHFVTGLLLATIICPYTKVLDVTIIVLSVGDSASTIAGKAIG
HHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHC
RIPIPYSSRKTVEGSLVGFTAAALASLAWTGDVVVSALAAGVGMLVESLPTPNDNVTIPV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
AVSVALGFWWGLL
HHHHHHHHHHHCC
>Mature Secondary Structure 
TSKELGRQLIHATFGLLFLLPLHMLGVYEFALLLLSGLIAGVSVSFALRRGLHVPIAKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LVDAFERPDEMHIPGQGTLHFVTGLLLATIICPYTKVLDVTIIVLSVGDSASTIAGKAIG
HHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHC
RIPIPYSSRKTVEGSLVGFTAAALASLAWTGDVVVSALAAGVGMLVESLPTPNDNVTIPV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
AVSVALGFWWGLL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]