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The map label for this gene is 20094399

Identifier: 20094399

GI number: 20094399

Start: 923724

End: 924575

Strand: Direct

Name: 20094399

Synonym: MK0963

Alternate gene names: NA

Gene position: 923724-924575 (Clockwise)

Preceding gene: 20094398

Following gene: 20094400

Centisome position: 54.5

GC content: 62.79

Gene sequence:

>852_bases
GTGGAGCGATCCCCGGCCGTCGCGGGTCAGTTCTACCCCGCCGACCCGGAGGAGTTGAGGAAGATGATCGAGTGGTGCTT
CCGACACGAGCTAGGACCCGGTGATCTACCCGAGACTAACGACGGTCCCTGTACCTTGCCCGGCGTGGTGGCGCCGCACG
CCGGTTATCAGTTCTCGGGACCGGTGGCCGCCCATACGTACAAGGTTCTGGCGGAGTCAGGAACCCCCGAGACGGTGGTG
ATACTGGGACCGAATCACACCGGGCTTGGGTCCGCGGTCGCCACGATGACGGACGGTGCTTGGCGCACGCCGCTGGGATC
GGTGGAGATCGACTCCGAGTTCGCGACCGCGCTGGTACGGAAGTGCGGCGTGATGGACGACGACTTAACGGCCCACGCTA
ACGAGCACTCCATCGAAGTACAGCTGCCGTTCCTCCAGTACGTGTACGGGGAGAGTTTCCGGTTCGTTCCCGTCTGTATG
GCGATGCACGACCTTCAGACCGCGAGGGAAGTAGGTGAGGCGATCGTGGACGTGGCGGAGGAGCTGGATAGGAACACGGT
GGTCATCGCGAGCACCGACTTCACGCACTACGAGCCGCACGATCAGGCCCAGAAAAAGGATCGTAAGGTCATCGAACGGA
TCACGGCCCTCGACGAGGCCGGTATGATCGAGATCGTGGAGCGATACAACGTCAGTATGTGCGGCGTAGGACCGACCGCC
GCGACCATAGTGGCGGTCAAGGCCATGGGTGCCTCCGAGGGGGAGCTCCTGAAGTACGCGACCAGTGGAGACGTTTCCGG
AGATTACTCTCAGGTGGTCGGTTACGCCGCTATCGTTTTCCGCCGCGGGTGA

Upstream 100 bases:

>100_bases
ATCGCTGGTGGAACGCAGGCACTTCGGCTATTACCTGGAGCGCTATTACGACCCGGAGGAACGAAGGTACCGCGGGTGAG
CCGACGTGTCATCGGGGGCC

Downstream 100 bases:

>100_bases
CGACGGATGCACCCGATCGAGTCGTTGGATCTAGCGTTGACGGCGCTCATCGCGGGCTTGATCCTCACGTCGGAGGCGCT
GCGCCTCTTCCCGTTCCTGT

Product: dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MERSPAVAGQFYPADPEELRKMIEWCFRHELGPGDLPETNDGPCTLPGVVAPHAGYQFSGPVAAHTYKVLAESGTPETVV
ILGPNHTGLGSAVATMTDGAWRTPLGSVEIDSEFATALVRKCGVMDDDLTAHANEHSIEVQLPFLQYVYGESFRFVPVCM
AMHDLQTAREVGEAIVDVAEELDRNTVVIASTDFTHYEPHDQAQKKDRKVIERITALDEAGMIEIVERYNVSMCGVGPTA
ATIVAVKAMGASEGELLKYATSGDVSGDYSQVVGYAAIVFRRG

Sequences:

>Translated_283_residues
MERSPAVAGQFYPADPEELRKMIEWCFRHELGPGDLPETNDGPCTLPGVVAPHAGYQFSGPVAAHTYKVLAESGTPETVV
ILGPNHTGLGSAVATMTDGAWRTPLGSVEIDSEFATALVRKCGVMDDDLTAHANEHSIEVQLPFLQYVYGESFRFVPVCM
AMHDLQTAREVGEAIVDVAEELDRNTVVIASTDFTHYEPHDQAQKKDRKVIERITALDEAGMIEIVERYNVSMCGVGPTA
ATIVAVKAMGASEGELLKYATSGDVSGDYSQVVGYAAIVFRRG
>Mature_283_residues
MERSPAVAGQFYPADPEELRKMIEWCFRHELGPGDLPETNDGPCTLPGVVAPHAGYQFSGPVAAHTYKVLAESGTPETVV
ILGPNHTGLGSAVATMTDGAWRTPLGSVEIDSEFATALVRKCGVMDDDLTAHANEHSIEVQLPFLQYVYGESFRFVPVCM
AMHDLQTAREVGEAIVDVAEELDRNTVVIASTDFTHYEPHDQAQKKDRKVIERITALDEAGMIEIVERYNVSMCGVGPTA
ATIVAVKAMGASEGELLKYATSGDVSGDYSQVVGYAAIVFRRG

Specific function: Unknown

COG id: COG1355

COG function: function code R; Predicted dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0103 family

Homologues:

Organism=Homo sapiens, GI7705720, Length=296, Percent_Identity=25.6756756756757, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25146594, Length=287, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32566861, Length=287, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6322467, Length=215, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357419, Length=303, Percent_Identity=26.7326732673267, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y963_METKA (Q8TWR9)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614246.1
- ProteinModelPortal:   Q8TWR9
- SMR:   Q8TWR9
- GeneID:   1477064
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0963
- NMPDR:   fig|190192.1.peg.959
- HOGENOM:   HBG575564
- OMA:   GPNHTGY
- ProtClustDB:   CLSK213947
- BioCyc:   MKAN190192:MK0963-MONOMER
- HAMAP:   MF_00055
- InterPro:   IPR020619
- InterPro:   IPR002737
- PANTHER:   PTHR11060

Pfam domain/function: PF01875 Memo

EC number: NA

Molecular weight: Translated: 30564; Mature: 30564

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSPAVAGQFYPADPEELRKMIEWCFRHELGPGDLPETNDGPCTLPGVVAPHAGYQFSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVAAHTYKVLAESGTPETVVILGPNHTGLGSAVATMTDGAWRTPLGSVEIDSEFATALVR
CHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEECHHHHHHHHH
KCGVMDDDLTAHANEHSIEVQLPFLQYVYGESFRFVPVCMAMHDLQTAREVGEAIVDVAE
HCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDRNTVVIASTDFTHYEPHDQAQKKDRKVIERITALDEAGMIEIVERYNVSMCGVGPTA
HCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCHH
ATIVAVKAMGASEGELLKYATSGDVSGDYSQVVGYAAIVFRRG
HHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEECC
>Mature Secondary Structure
MERSPAVAGQFYPADPEELRKMIEWCFRHELGPGDLPETNDGPCTLPGVVAPHAGYQFSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVAAHTYKVLAESGTPETVVILGPNHTGLGSAVATMTDGAWRTPLGSVEIDSEFATALVR
CHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEECHHHHHHHHH
KCGVMDDDLTAHANEHSIEVQLPFLQYVYGESFRFVPVCMAMHDLQTAREVGEAIVDVAE
HCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDRNTVVIASTDFTHYEPHDQAQKKDRKVIERITALDEAGMIEIVERYNVSMCGVGPTA
HCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCHH
ATIVAVKAMGASEGELLKYATSGDVSGDYSQVVGYAAIVFRRG
HHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014