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The map label for this gene is 20094376

Identifier: 20094376

GI number: 20094376

Start: 898801

End: 899631

Strand: Reverse

Name: 20094376

Synonym: MK0940

Alternate gene names: NA

Gene position: 899631-898801 (Counterclockwise)

Preceding gene: 20094377

Following gene: 20094374

Centisome position: 53.08

GC content: 65.7

Gene sequence:

>831_bases
GTGCTGTCCCGCGAGGAGTTCGCGCGGAGACTGGAGGAGGAACTGCCGGATGTCGCGGACTCGGTACCACACCGTTGGCA
GGAGCTGGGCGATGTGGTAGTCATCCGGTTGTTCGACGAGCGGGCGTGGGCGTACCGACGGGAGGTGGGACGGATCCTCC
GTGAGGTGACCGGGGCGCGATCGGTGGTGGCGCTACGCCGCGTGAGTGGAACGTTTCGAGAGCCGGTTGGGGAGGTCGTA
GCGGGGGATCGGAACGCGGAAACCGTGCACCGGGAGCTGGGAATCCGGTTCAAGTTGGACCCGACGCGGGTGATGTTCGC
ACGGGGGAACCTGGAGGAGCGCCGCCGGCTGCTGGAATCGGACCTGGAAGGAAAGCTTGTGTTCGACATGTTCGCCGGGA
TCGGTTACTTCACGCTACCGGCGGCACTGGCGGGGGCGGAGGTGATAGCGGCAGAGCTGAACCCCGTGGCGTGCCGGTAC
CTGGTGGAGAACGCGCGGCTGAACGGTGTGGAAGGGCGGGTACGAGTGTTCTTAGGGGACTGTCGAGAGGTGGCACGGTT
CGTGCGGGCGGCGGACCGGGTGTTGATGGGGTATCTGAAGGGGACGCTGAAGTTCTTGCCGTACGCGTGTCGGGCGGTAC
GGGACGGTGGAGTCCTGGTCGTACACGAGGTGTTCCAGAAGCGATGGGGAGAGGACCGGGTGGCCCGAGAAGTGCTGAAC
GCGCTGCCGGATGGTTTTGAGGGCGAGGTACTGGAAGTACGGCGCGTGAAGAGTTTCTCCCCGGCGTTGGACCACTACGC
GGTGGAGCTGCGGGTCCGACGGCGGAGGTAA

Upstream 100 bases:

>100_bases
CTCGAACGAGGTGTGGTGTTCGTGGATACCTCACGAGCGCAGCGGGCGTCGGGTTACGCACGGGCGTTGCGACTGGCGGC
CGAGCTGGCGGGGGGATGAA

Downstream 100 bases:

>100_bases
TCGACGATCTCGCGGAGGGCGACGTCGGCGCGGGGCCCCATTCCGAGCATATCGTTGAGCCAATAGGAGGCGAGCATACC
GACGACGCGGTCGTTCTGGA

Product: SAM-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLSREEFARRLEEELPDVADSVPHRWQELGDVVVIRLFDERAWAYRREVGRILREVTGARSVVALRRVSGTFREPVGEVV
AGDRNAETVHRELGIRFKLDPTRVMFARGNLEERRRLLESDLEGKLVFDMFAGIGYFTLPAALAGAEVIAAELNPVACRY
LVENARLNGVEGRVRVFLGDCREVARFVRAADRVLMGYLKGTLKFLPYACRAVRDGGVLVVHEVFQKRWGEDRVAREVLN
ALPDGFEGEVLEVRRVKSFSPALDHYAVELRVRRRR

Sequences:

>Translated_276_residues
MLSREEFARRLEEELPDVADSVPHRWQELGDVVVIRLFDERAWAYRREVGRILREVTGARSVVALRRVSGTFREPVGEVV
AGDRNAETVHRELGIRFKLDPTRVMFARGNLEERRRLLESDLEGKLVFDMFAGIGYFTLPAALAGAEVIAAELNPVACRY
LVENARLNGVEGRVRVFLGDCREVARFVRAADRVLMGYLKGTLKFLPYACRAVRDGGVLVVHEVFQKRWGEDRVAREVLN
ALPDGFEGEVLEVRRVKSFSPALDHYAVELRVRRRR
>Mature_276_residues
MLSREEFARRLEEELPDVADSVPHRWQELGDVVVIRLFDERAWAYRREVGRILREVTGARSVVALRRVSGTFREPVGEVV
AGDRNAETVHRELGIRFKLDPTRVMFARGNLEERRRLLESDLEGKLVFDMFAGIGYFTLPAALAGAEVIAAELNPVACRY
LVENARLNGVEGRVRVFLGDCREVARFVRAADRVLMGYLKGTLKFLPYACRAVRDGGVLVVHEVFQKRWGEDRVAREVLN
ALPDGFEGEVLEVRRVKSFSPALDHYAVELRVRRRR

Specific function: Unknown

COG id: COG2520

COG function: function code R; Predicted methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase trmD family [H]

Homologues:

Organism=Homo sapiens, GI157388919, Length=214, Percent_Identity=34.1121495327103, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI145275187, Length=173, Percent_Identity=27.7456647398844, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI212646412, Length=212, Percent_Identity=28.7735849056604, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45551508, Length=163, Percent_Identity=28.8343558282209, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10 [H]

EC number: NA

Molecular weight: Translated: 31518; Mature: 31518

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00334 MYB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSREEFARRLEEELPDVADSVPHRWQELGDVVVIRLFDERAWAYRREVGRILREVTGAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHH
SVVALRRVSGTFREPVGEVVAGDRNAETVHRELGIRFKLDPTRVMFARGNLEERRRLLES
HHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCCEEEEECCCHHHHHHHHHC
DLEGKLVFDMFAGIGYFTLPAALAGAEVIAAELNPVACRYLVENARLNGVEGRVRVFLGD
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHH
CREVARFVRAADRVLMGYLKGTLKFLPYACRAVRDGGVLVVHEVFQKRWGEDRVAREVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHH
ALPDGFEGEVLEVRRVKSFSPALDHYAVELRVRRRR
HCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSREEFARRLEEELPDVADSVPHRWQELGDVVVIRLFDERAWAYRREVGRILREVTGAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHCHH
SVVALRRVSGTFREPVGEVVAGDRNAETVHRELGIRFKLDPTRVMFARGNLEERRRLLES
HHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCCEEEEECCCHHHHHHHHHC
DLEGKLVFDMFAGIGYFTLPAALAGAEVIAAELNPVACRYLVENARLNGVEGRVRVFLGD
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHH
CREVARFVRAADRVLMGYLKGTLKFLPYACRAVRDGGVLVVHEVFQKRWGEDRVAREVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHH
ALPDGFEGEVLEVRRVKSFSPALDHYAVELRVRRRR
HCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]