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The map label for this gene is 20094240

Identifier: 20094240

GI number: 20094240

Start: 764701

End: 765237

Strand: Direct

Name: 20094240

Synonym: MK0803

Alternate gene names: NA

Gene position: 764701-765237 (Clockwise)

Preceding gene: 20094238

Following gene: 20094241

Centisome position: 45.12

GC content: 59.59

Gene sequence:

>537_bases
TTGGAACTTGAGCCGAGGACGGTAGTTCTCAGGCTGGGACATCGGCGCGAGCGGGACAAGCGGATCACGACGCACGTATG
TCTGACGGCTCGAGCGTTCGGAGCCGCCGGTGTGCTGATCTCGGGTGACCATGATGAATCGGTGATCGAGTCCGTCGAGG
ACGTCGTCGAGCGATGGGGCGGCCCCTTCACCGTGCAGTGGGTGGGGAATTGGAGACGTGTGATCAAAGATTGGAAACGT
TCGGGTGGATCCGTAGTTCACCTCACGATGTACGGTTTGCATATAGACGACGTGATCGGAGAGTTGCGAGGGGAGAATGA
ACTGCTCGTGATCGTAGGCGCCGGCAAGGTCCCTGCCGAGGTCTTCGAGCTTTCGGACTACAACGTCGCCATAGGCCATC
AACCCCACTCCGAGGTGGCCGCGCTCGCCGTCTTTCTCGACCGACTCTACGAGGGCAAGGAACTTCATCGGGAGTTCGAG
CGGGCTAGGTTGAGGGTCGTACCCTCGGAGAAAGGGAAGAAGGTGGAGCGACTATGA

Upstream 100 bases:

>100_bases
GGACCCGCGAGCAGCAGTAACGTGAACAGCATCGGCAGCATCCGAGGCCCCGGAAGCGAGTGGTGATGGCGGTGAATAAA
TTTCGCAAGGGGCTGAGAGG

Downstream 100 bases:

>100_bases
CGGTGGAGATCGCCGTGATATCGGACGTTCATTCGAACCTCGAGGCGCTGAAGCGGGTGCTGCGGGAAGTACGATCGGCC
GACATGTTGGTGTGCTGCGG

Product: SpoU-like RNA methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MELEPRTVVLRLGHRRERDKRITTHVCLTARAFGAAGVLISGDHDESVIESVEDVVERWGGPFTVQWVGNWRRVIKDWKR
SGGSVVHLTMYGLHIDDVIGELRGENELLVIVGAGKVPAEVFELSDYNVAIGHQPHSEVAALAVFLDRLYEGKELHREFE
RARLRVVPSEKGKKVERL

Sequences:

>Translated_178_residues
MELEPRTVVLRLGHRRERDKRITTHVCLTARAFGAAGVLISGDHDESVIESVEDVVERWGGPFTVQWVGNWRRVIKDWKR
SGGSVVHLTMYGLHIDDVIGELRGENELLVIVGAGKVPAEVFELSDYNVAIGHQPHSEVAALAVFLDRLYEGKELHREFE
RARLRVVPSEKGKKVERL
>Mature_178_residues
MELEPRTVVLRLGHRRERDKRITTHVCLTARAFGAAGVLISGDHDESVIESVEDVVERWGGPFTVQWVGNWRRVIKDWKR
SGGSVVHLTMYGLHIDDVIGELRGENELLVIVGAGKVPAEVFELSDYNVAIGHQPHSEVAALAVFLDRLYEGKELHREFE
RARLRVVPSEKGKKVERL

Specific function: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs

COG id: COG1303

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aTrm56 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRM56_METKA (Q8TX72)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614087.1
- ProteinModelPortal:   Q8TX72
- SMR:   Q8TX72
- GeneID:   1476904
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0803
- NMPDR:   fig|190192.1.peg.800
- HOGENOM:   HBG297370
- OMA:   GHRPERD
- BioCyc:   MKAN190192:MK0803-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00077
- InterPro:   IPR002845
- PIRSF:   PIRSF016123
- ProDom:   PD016584

Pfam domain/function: PF01994 DUF127

EC number: NA

Molecular weight: Translated: 20124; Mature: 20124

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: BINDING 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEPRTVVLRLGHRRERDKRITTHVCLTARAFGAAGVLISGDHDESVIESVEDVVERWG
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCC
GPFTVQWVGNWRRVIKDWKRSGGSVVHLTMYGLHIDDVIGELRGENELLVIVGAGKVPAE
CCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCHH
VFELSDYNVAIGHQPHSEVAALAVFLDRLYEGKELHREFERARLRVVPSEKGKKVERL
HEECCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCCC
>Mature Secondary Structure
MELEPRTVVLRLGHRRERDKRITTHVCLTARAFGAAGVLISGDHDESVIESVEDVVERWG
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCC
GPFTVQWVGNWRRVIKDWKRSGGSVVHLTMYGLHIDDVIGELRGENELLVIVGAGKVPAE
CCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCHH
VFELSDYNVAIGHQPHSEVAALAVFLDRLYEGKELHREFERARLRVVPSEKGKKVERL
HEECCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014