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The map label for this gene is SucC [H]

Identifier: 20094168

GI number: 20094168

Start: 697284

End: 698363

Strand: Direct

Name: SucC [H]

Synonym: MK0731

Alternate gene names: 20094168

Gene position: 697284-698363 (Clockwise)

Preceding gene: 20094167

Following gene: 20094169

Centisome position: 41.14

GC content: 62.78

Gene sequence:

>1080_bases
ATGATCAGGCTGTTGGAGTACCAGGCTAAGCATCTGCTCAAGGAGGCCGGGGTGCCGATTCCAGAAGGCGACGTCGCCCG
CACCTCGGCGGACGCGGCCCGGATCGCCGCCGAACTCGGGGGACCGGTGGCCGTCAAGGCGCAGGTGCCCGTCGGGGCCC
GTGGTAAAGCCGGGGGTATCCTGTTCGCGGACGACCCGGAAGGGGCCAGAAAGGCCGCCCGGAAGCTGCTCGGCTCGCGG
ATCCGGGGTGAGACCGTCAGGAAGGTGCTCGTGGAAGAGAAACTGGACATAGCCGAGGAATGGTACGTGTCCATAACGCT
CGACCGTGCGAAGCGTAGGCCCGTACTCCTCGTCTCCCGCGAAGGTGGAGTAGATATCGAAGAGGTTCCGGACGAGAAGA
TCGCCCGCAGGTACCTCGACCCGATCCTAGGATTACGCCCCTTCGAAGCTCGAGAGGCGATCCTCGAGGCGGGTATCCCG
AAGGAGCACCTGCGGGACGTCGAGGAAGTGATCACATCCATGTACGAGGTGTTCGAGAGCTACGACGCTCACCTCGTGGA
GATCAACCCGCTAGTTCTTACGGAGAACGGGGAGGTAGTGGCCGCGGACGCTGTCGTGAACCTGGACGAAGACGCCGCCA
ATATCCGGCACCCGGAGTTCGCCGAAGAGACCCGCGATTTCCCCTTCGTCGAGCTCGACGGTGACATCGGTATCATCGCC
AACGGTGCGGGTCTCACCATGGCCACCATAGATCTCGTTAAGGATCTCGGTGGTAAGCCCGCCAACTTCTTGGACGTAGG
TGGTGGGGCTTACCCGACGCTCATCCGTAGAGCCATCCTCACCGTGGCCGAGCTGGACGTGAAAGTGATCCTCCTCAACA
TCTTCGGTGGCATCACTCGGTGTGACGAGGTGGCGGAAGGTATCGTTCAAGCCCTCGACGACGTGGACGTCCCGCTCGTG
GTGAGGCTCGTGGGGACGAACGAGGAGGAAGGTCATCGCATACTCCGCGAGCACGGGGTCGACGTCTACACCGAGCTTAA
GGAGGCGGTCGAACGCGCGGTCGAGTTAGCGGGGGCTTAG

Upstream 100 bases:

>100_bases
CGTTCGACTCACTACGAAAGGCCGTCGAGGATTCCGTACCGCCCGGGACGGAGGACGTCAACGTCCGGGCCCTCAAGCTC
GGAGCCCGGGAGGTGAGGGA

Downstream 100 bases:

>100_bases
CCCTTGTTAGACTCAGACACGCGCGTCCTCGTGCAGGGTATCACGGGCCGGCACGGAAGTTTCCATACGAAGCTAATGCT
GGAGTACGGGACCGAAATCG

Product: succinyl-CoA synthetase beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MIRLLEYQAKHLLKEAGVPIPEGDVARTSADAARIAAELGGPVAVKAQVPVGARGKAGGILFADDPEGARKAARKLLGSR
IRGETVRKVLVEEKLDIAEEWYVSITLDRAKRRPVLLVSREGGVDIEEVPDEKIARRYLDPILGLRPFEAREAILEAGIP
KEHLRDVEEVITSMYEVFESYDAHLVEINPLVLTENGEVVAADAVVNLDEDAANIRHPEFAEETRDFPFVELDGDIGIIA
NGAGLTMATIDLVKDLGGKPANFLDVGGGAYPTLIRRAILTVAELDVKVILLNIFGGITRCDEVAEGIVQALDDVDVPLV
VRLVGTNEEEGHRILREHGVDVYTELKEAVERAVELAGA

Sequences:

>Translated_359_residues
MIRLLEYQAKHLLKEAGVPIPEGDVARTSADAARIAAELGGPVAVKAQVPVGARGKAGGILFADDPEGARKAARKLLGSR
IRGETVRKVLVEEKLDIAEEWYVSITLDRAKRRPVLLVSREGGVDIEEVPDEKIARRYLDPILGLRPFEAREAILEAGIP
KEHLRDVEEVITSMYEVFESYDAHLVEINPLVLTENGEVVAADAVVNLDEDAANIRHPEFAEETRDFPFVELDGDIGIIA
NGAGLTMATIDLVKDLGGKPANFLDVGGGAYPTLIRRAILTVAELDVKVILLNIFGGITRCDEVAEGIVQALDDVDVPLV
VRLVGTNEEEGHRILREHGVDVYTELKEAVERAVELAGA
>Mature_359_residues
MIRLLEYQAKHLLKEAGVPIPEGDVARTSADAARIAAELGGPVAVKAQVPVGARGKAGGILFADDPEGARKAARKLLGSR
IRGETVRKVLVEEKLDIAEEWYVSITLDRAKRRPVLLVSREGGVDIEEVPDEKIARRYLDPILGLRPFEAREAILEAGIP
KEHLRDVEEVITSMYEVFESYDAHLVEINPLVLTENGEVVAADAVVNLDEDAANIRHPEFAEETRDFPFVELDGDIGIIA
NGAGLTMATIDLVKDLGGKPANFLDVGGGAYPTLIRRAILTVAELDVKVILLNIFGGITRCDEVAEGIVQALDDVDVPLV
VRLVGTNEEEGHRILREHGVDVYTELKEAVERAVELAGA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=36.4795918367347, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI157779135, Length=379, Percent_Identity=36.1477572559367, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=36.6391184573003, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1786948, Length=369, Percent_Identity=39.0243902439024, Blast_Score=228, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=35.1898734177215, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=33.0788804071247, Blast_Score=197, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=34.1772151898734, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=36.2244897959184, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=34.9489795918367, Blast_Score=195, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=34.9489795918367, Blast_Score=195, Evalue=3e-50,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=35.1145038167939, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=35.1145038167939, Blast_Score=194, Evalue=6e-50,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 38976; Mature: 38976

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLLEYQAKHLLKEAGVPIPEGDVARTSADAARIAAELGGPVAVKAQVPVGARGKAGGI
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCE
LFADDPEGARKAARKLLGSRIRGETVRKVLVEEKLDIAEEWYVSITLDRAKRRPVLLVSR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEEECCCCCCEEEEEC
EGGVDIEEVPDEKIARRYLDPILGLRPFEAREAILEAGIPKEHLRDVEEVITSMYEVFES
CCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
YDAHLVEINPLVLTENGEVVAADAVVNLDEDAANIRHPEFAEETRDFPFVELDGDIGIIA
CCCEEEEECEEEEECCCCEEEEEEEEECCCCHHHCCCCCHHHHHCCCCEEEECCCEEEEE
NGAGLTMATIDLVKDLGGKPANFLDVGGGAYPTLIRRAILTVAELDVKVILLNIFGGITR
CCCCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
CDEVAEGIVQALDDVDVPLVVRLVGTNEEEGHRILREHGVDVYTELKEAVERAVELAGA
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRLLEYQAKHLLKEAGVPIPEGDVARTSADAARIAAELGGPVAVKAQVPVGARGKAGGI
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCE
LFADDPEGARKAARKLLGSRIRGETVRKVLVEEKLDIAEEWYVSITLDRAKRRPVLLVSR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEEECCCCCCEEEEEC
EGGVDIEEVPDEKIARRYLDPILGLRPFEAREAILEAGIPKEHLRDVEEVITSMYEVFES
CCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
YDAHLVEINPLVLTENGEVVAADAVVNLDEDAANIRHPEFAEETRDFPFVELDGDIGIIA
CCCEEEEECEEEEECCCCEEEEEEEEECCCCHHHCCCCCHHHHHCCCCEEEECCCEEEEE
NGAGLTMATIDLVKDLGGKPANFLDVGGGAYPTLIRRAILTVAELDVKVILLNIFGGITR
CCCCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
CDEVAEGIVQALDDVDVPLVVRLVGTNEEEGHRILREHGVDVYTELKEAVERAVELAGA
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA