Click here to switch to the map view.

The map label for this gene is 20094102

Identifier: 20094102

GI number: 20094102

Start: 622607

End: 624328

Strand: Direct

Name: 20094102

Synonym: MK0664

Alternate gene names: NA

Gene position: 622607-624328 (Clockwise)

Preceding gene: 20094100

Following gene: 20094103

Centisome position: 36.73

GC content: 65.16

Gene sequence:

>1722_bases
TTGCGAGTCCTGTGCGTATGCTCCGGCACGATGTTGAAAGCCGCCCGAGACGTCGCGGAGCGGTTCTCCGAGCTGAAAAT
CGACGTAGCTTACCAGGACGATCCGATCGACCCGAATCGGTACGACCTCATCGTGCTACTGAAGGTAACGAACGTGAACC
TTCCGACGGATCACGACGCCGAGGTCGTCGCCGTGCCCCTCGACGGTTCCACCGGGATACAGCATCTGAACACTGCCCCG
TCGAGCGTCGTCGAGCGGGCCGCGGAGTACCTGGAGAAGGGCGGGAAGGAAAACCTCGAGAATGAGCGCGGGTTCGAGTC
GTTCGAGAAGCTCGGTGTACCCGTCCTGAACGCCGTGGTGTCGTGGTACACCGACCGGGACGGGTGGCGGGAGTCCGAGG
GAGGGCTCTCACCGGCCGACGTGGCGTACGGAATATCCCTGGCGGAGCTCCAGGGTAGGATCGATCCGGTGCTGGTCGGG
ACCAAGCGCGATCGTGGAGAGTTCGAGCCCTTACCCGAGCGGTGCCGGCTCGCCGCACGACGTGCCATCCGGTGGGCTCG
ACTCAGGCGCAAGGACCCCGCCGAGCGTCGCGTCGCCGTGGTGCTCAACAACGGGATATGCTCCGGAGGGGAGGCGAGGA
TCGGTGCTGCTATGGGACTGGACACGTTCGAGAGTCTCGCTCGACTGCTGCAGCACATGGCCGAGGAGGGGTACCGGCTC
GACTGGGTACCCAGGGACGGTCGGGAGCTGGAGCGCGAGTTCTTCCGGAGGAAGGCCTTCGACGAGTTCAAGCGCACGCG
CGTGGAGGATATCGTCGCGTCCGGTGGGGCCGTGGACCTCGTTCCCCTCGATAGGTACCTCGAGTGGTTCGAGGAGCTCC
CGGAGGAGCTCCAGGAGCGTATGGTCGAGACCTGGGGTGAACCTCCGGGCGACTCCATGGTGCTCGACGACCACCTAGTC
ATCGCCGGGATCCGAACGGGGAACGTGTTCCTGACCGTTCAGCCGAAGCGCGGCTGCGCCGGTACCGAGTGCAACGGGGA
CGTCTGCAAGATCCTTCACGATCCACACTGCCCGCCGACGCACCATTACTACGCGTTCTACCGGTGGATCAGGGACGAGT
TCCGGGCCGACGTGTTACTCCACGCCGGCACCCACGGGACCCTCGAGTGGTTGCCGGGGAAGTCCGTGGGACTGTCCCGA
GAGTGTTGGCCCGAGGTGTGCTTGGGCGACCTGCCGGTAGTGTACTGGTACATCGTGAGCAATCCCTCGGAGGGAGTCCA
GGCCAAACGCCGCGGGTACTCGACGCTAGTGGATCACTGCCCGCCCCCGATGGGGACTACCGAGGCCGGCCTAGAGGAGC
TCGAGGAGCGGCTCGAAGAGGCGCTGCGCGACCCGGATCGCGAGGACCGGCGGCTCTTCGAGGAATGGGAGGTCCGCTCG
GGGGCCTTCATCGAAAAGGGCTTACACGTGATCGGCGAACCCGCGTACGACCCGGAGCGTCTCTCGGAGTTCCTGTTCGC
TCTCTGTAGGAACCGACTCCGAGAGCTGATCGCGGAGTCGGCTGGGCTGGATCTGGAGGAGCTGACCGAGCGTCCCGAGG
CGGAGAACGACCTGTTCGGCGCCACGAACGCCGAGGTGCTGAGAGCCCTCGATGCGGTGATCCGAGGACTGTGTGAGGAG
ACCGTCTCGGAGGCACACCACGGACCCGACCGAAAAGGATAA

Upstream 100 bases:

>100_bases
GTTTCCGGAGCTCCTCTTCGAGCTCCAACCTCGGCACCCCGGGCGTTGGTAGCACGAAAGCGATTCAAGGTAATACAGAA
TAAGTGTTCGGGGATCACCG

Downstream 100 bases:

>100_bases
CCTCCCCGGATCTCGGGACCCGCACGGGCTAACCTATGGGATTATTCTCCAAGCTCTTCCGTCGCGGACCGAAGCCTCAA
ATCGCGGAGAGCGAGCGGGT

Product: hypothetical protein

Products: ADP; phosphate; cob(II)yrinic acid a,c-diamide; H+

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MRVLCVCSGTMLKAARDVAERFSELKIDVAYQDDPIDPNRYDLIVLLKVTNVNLPTDHDAEVVAVPLDGSTGIQHLNTAP
SSVVERAAEYLEKGGKENLENERGFESFEKLGVPVLNAVVSWYTDRDGWRESEGGLSPADVAYGISLAELQGRIDPVLVG
TKRDRGEFEPLPERCRLAARRAIRWARLRRKDPAERRVAVVLNNGICSGGEARIGAAMGLDTFESLARLLQHMAEEGYRL
DWVPRDGRELEREFFRRKAFDEFKRTRVEDIVASGGAVDLVPLDRYLEWFEELPEELQERMVETWGEPPGDSMVLDDHLV
IAGIRTGNVFLTVQPKRGCAGTECNGDVCKILHDPHCPPTHHYYAFYRWIRDEFRADVLLHAGTHGTLEWLPGKSVGLSR
ECWPEVCLGDLPVVYWYIVSNPSEGVQAKRRGYSTLVDHCPPPMGTTEAGLEELEERLEEALRDPDREDRRLFEEWEVRS
GAFIEKGLHVIGEPAYDPERLSEFLFALCRNRLRELIAESAGLDLEELTERPEAENDLFGATNAEVLRALDAVIRGLCEE
TVSEAHHGPDRKG

Sequences:

>Translated_573_residues
MRVLCVCSGTMLKAARDVAERFSELKIDVAYQDDPIDPNRYDLIVLLKVTNVNLPTDHDAEVVAVPLDGSTGIQHLNTAP
SSVVERAAEYLEKGGKENLENERGFESFEKLGVPVLNAVVSWYTDRDGWRESEGGLSPADVAYGISLAELQGRIDPVLVG
TKRDRGEFEPLPERCRLAARRAIRWARLRRKDPAERRVAVVLNNGICSGGEARIGAAMGLDTFESLARLLQHMAEEGYRL
DWVPRDGRELEREFFRRKAFDEFKRTRVEDIVASGGAVDLVPLDRYLEWFEELPEELQERMVETWGEPPGDSMVLDDHLV
IAGIRTGNVFLTVQPKRGCAGTECNGDVCKILHDPHCPPTHHYYAFYRWIRDEFRADVLLHAGTHGTLEWLPGKSVGLSR
ECWPEVCLGDLPVVYWYIVSNPSEGVQAKRRGYSTLVDHCPPPMGTTEAGLEELEERLEEALRDPDREDRRLFEEWEVRS
GAFIEKGLHVIGEPAYDPERLSEFLFALCRNRLRELIAESAGLDLEELTERPEAENDLFGATNAEVLRALDAVIRGLCEE
TVSEAHHGPDRKG
>Mature_573_residues
MRVLCVCSGTMLKAARDVAERFSELKIDVAYQDDPIDPNRYDLIVLLKVTNVNLPTDHDAEVVAVPLDGSTGIQHLNTAP
SSVVERAAEYLEKGGKENLENERGFESFEKLGVPVLNAVVSWYTDRDGWRESEGGLSPADVAYGISLAELQGRIDPVLVG
TKRDRGEFEPLPERCRLAARRAIRWARLRRKDPAERRVAVVLNNGICSGGEARIGAAMGLDTFESLARLLQHMAEEGYRL
DWVPRDGRELEREFFRRKAFDEFKRTRVEDIVASGGAVDLVPLDRYLEWFEELPEELQERMVETWGEPPGDSMVLDDHLV
IAGIRTGNVFLTVQPKRGCAGTECNGDVCKILHDPHCPPTHHYYAFYRWIRDEFRADVLLHAGTHGTLEWLPGKSVGLSR
ECWPEVCLGDLPVVYWYIVSNPSEGVQAKRRGYSTLVDHCPPPMGTTEAGLEELEERLEEALRDPDREDRRLFEEWEVRS
GAFIEKGLHVIGEPAYDPERLSEFLFALCRNRLRELIAESAGLDLEELTERPEAENDLFGATNAEVLRALDAVIRGLCEE
TVSEAHHGPDRKG

Specific function: Unknown

COG id: COG1429

COG function: function code H; Cobalamin biosynthesis protein CobN and related Mg-chelatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunit H family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003672 [H]

Pfam domain/function: PF02514 CobN-Mg_chel [H]

EC number: 6.6.1.2

Molecular weight: Translated: 64580; Mature: 64580

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLCVCSGTMLKAARDVAERFSELKIDVAYQDDPIDPNRYDLIVLLKVTNVNLPTDHDA
CEEEEEECCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCC
EVVAVPLDGSTGIQHLNTAPSSVVERAAEYLEKGGKENLENERGFESFEKLGVPVLNAVV
CEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHCHHHHHHHH
SWYTDRDGWRESEGGLSPADVAYGISLAELQGRIDPVLVGTKRDRGEFEPLPERCRLAAR
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHH
RAIRWARLRRKDPAERRVAVVLNNGICSGGEARIGAAMGLDTFESLARLLQHMAEEGYRL
HHHHHHHHHCCCCHHCEEEEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCCEE
DWVPRDGRELEREFFRRKAFDEFKRTRVEDIVASGGAVDLVPLDRYLEWFEELPEELQER
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
MVETWGEPPGDSMVLDDHLVIAGIRTGNVFLTVQPKRGCAGTECNGDVCKILHDPHCPPT
HHHHCCCCCCCCEEEECCEEEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCC
HHYYAFYRWIRDEFRADVLLHAGTHGTLEWLPGKSVGLSRECWPEVCLGDLPVVYWYIVS
CHHHHHHHHHHHHHHHCEEEECCCCCCEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEEC
NPSEGVQAKRRGYSTLVDHCPPPMGTTEAGLEELEERLEEALRDPDREDRRLFEEWEVRS
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GAFIEKGLHVIGEPAYDPERLSEFLFALCRNRLRELIAESAGLDLEELTERPEAENDLFG
CHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
ATNAEVLRALDAVIRGLCEETVSEAHHGPDRKG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRVLCVCSGTMLKAARDVAERFSELKIDVAYQDDPIDPNRYDLIVLLKVTNVNLPTDHDA
CEEEEEECCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCC
EVVAVPLDGSTGIQHLNTAPSSVVERAAEYLEKGGKENLENERGFESFEKLGVPVLNAVV
CEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHCHHHHHHHH
SWYTDRDGWRESEGGLSPADVAYGISLAELQGRIDPVLVGTKRDRGEFEPLPERCRLAAR
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHH
RAIRWARLRRKDPAERRVAVVLNNGICSGGEARIGAAMGLDTFESLARLLQHMAEEGYRL
HHHHHHHHHCCCCHHCEEEEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCCEE
DWVPRDGRELEREFFRRKAFDEFKRTRVEDIVASGGAVDLVPLDRYLEWFEELPEELQER
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
MVETWGEPPGDSMVLDDHLVIAGIRTGNVFLTVQPKRGCAGTECNGDVCKILHDPHCPPT
HHHHCCCCCCCCEEEECCEEEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCC
HHYYAFYRWIRDEFRADVLLHAGTHGTLEWLPGKSVGLSRECWPEVCLGDLPVVYWYIVS
CHHHHHHHHHHHHHHHCEEEECCCCCCEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEEC
NPSEGVQAKRRGYSTLVDHCPPPMGTTEAGLEELEERLEEALRDPDREDRRLFEEWEVRS
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GAFIEKGLHVIGEPAYDPERLSEFLFALCRNRLRELIAESAGLDLEELTERPEAENDLFG
CHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
ATNAEVLRALDAVIRGLCEETVSEAHHGPDRKG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Hydrogenobyrinic acid a,c diamide; Co2+

Specific reaction: ATP + hydrogenobyrinic acid a,c-diamide + Co2+ = ADP + phosphate + cob(II)yrinic acid a,c-diamide + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]