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The map label for this gene is MtrA [H]

Identifier: 20094098

GI number: 20094098

Start: 619299

End: 620057

Strand: Direct

Name: MtrA [H]

Synonym: MK0660

Alternate gene names: 20094098

Gene position: 619299-620057 (Clockwise)

Preceding gene: 20094097

Following gene: 20094099

Centisome position: 36.54

GC content: 61.66

Gene sequence:

>759_bases
GTGCTTGAGGTGCCCGAGAAAGCCGAACCGGCCGAGGGCTGGCCCGTGGTCGAGGGAGACTACGTCGTAGGTGATCCCGA
GGCTCCCGTCCACGTGGTCACGCTCGGATCCCACATCGAGGAGGACATCCTGAAGGCCGCCGGTGAGGACAAGGTAGCCA
TCGCCGGCCCCTGTAAGACCGAGAACATCGGAATCGAGAAGGTCATAGCCAACGTCATCGCCAACCCGAACATCAGGTTC
GGCGTGCTCTGCGGTGCGGAGGTAACCGGTCACCTCACGGGTCAGTGCTTCAAGGCCATGTACGAGAACGGTGTCGATCC
GGACTCCGGAGAGATCATCGGGGCGGAGGGCGCCATCCCGTACCTGGAGAACATCCCGGAAGAGGCCGTTGAGCGCTACC
GGGACCAGATCGTGGAGCTCGTCGACCTCATCGACGTCGAGGACGTCGACGAGATCGTCAAGGCGATCGAGGAGTGCGTG
GAGAAGGACCCCGGAGCGTACGAGGAAGGTCCGATGACCATCTCCCTCGAGGAGGAAGAAGAGGAGGAACTCGCGGAAGT
CGCCGGAATGCCGGTGTCCGCGGAGACCGTGACCGTGGAGTACCGCATTAACGACGTGCGAGTCGGAGTTAAGAGCATCG
GCGCCATGCAGAGATACATGGCGGGCTACCTCTCAGGACGCACGATGGGATTGCTGATAGGGATCATCTCAGGTATGATC
TTCCTGTTCCTGCCAATGGTCGTCCTGGGTGGCGTCTGA

Upstream 100 bases:

>100_bases
TCATAGGTACGATGATAGTGGCGCTCGTAGCCTTCACCCTCGCGGCCGTGTACAAGCTCCACGCCCTGCGCCTTCTCGGC
CTCTAATCCCTTCGTAGGGG

Downstream 100 bases:

>100_bases
GGGGGCAGTCACGTTGGCGGAAGAGGAGTCCGTTCCCAAGATGGTCGCTCCGGAAGACGACATCCGTGAAATCCACTCAC
GCTTGGACGAAATCGAGCGT

Product: tetrahydromethanopterin S-methyltransferase subunit A

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLEVPEKAEPAEGWPVVEGDYVVGDPEAPVHVVTLGSHIEEDILKAAGEDKVAIAGPCKTENIGIEKVIANVIANPNIRF
GVLCGAEVTGHLTGQCFKAMYENGVDPDSGEIIGAEGAIPYLENIPEEAVERYRDQIVELVDLIDVEDVDEIVKAIEECV
EKDPGAYEEGPMTISLEEEEEEELAEVAGMPVSAETVTVEYRINDVRVGVKSIGAMQRYMAGYLSGRTMGLLIGIISGMI
FLFLPMVVLGGV

Sequences:

>Translated_252_residues
MLEVPEKAEPAEGWPVVEGDYVVGDPEAPVHVVTLGSHIEEDILKAAGEDKVAIAGPCKTENIGIEKVIANVIANPNIRF
GVLCGAEVTGHLTGQCFKAMYENGVDPDSGEIIGAEGAIPYLENIPEEAVERYRDQIVELVDLIDVEDVDEIVKAIEECV
EKDPGAYEEGPMTISLEEEEEEELAEVAGMPVSAETVTVEYRINDVRVGVKSIGAMQRYMAGYLSGRTMGLLIGIISGMI
FLFLPMVVLGGV
>Mature_252_residues
MLEVPEKAEPAEGWPVVEGDYVVGDPEAPVHVVTLGSHIEEDILKAAGEDKVAIAGPCKTENIGIEKVIANVIANPNIRF
GVLCGAEVTGHLTGQCFKAMYENGVDPDSGEIIGAEGAIPYLENIPEEAVERYRDQIVELVDLIDVEDVDEIVKAIEECV
EKDPGAYEEGPMTISLEEEEEEELAEVAGMPVSAETVTVEYRINDVRVGVKSIGAMQRYMAGYLSGRTMGLLIGIISGMI
FLFLPMVVLGGV

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step [H]

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005778
- InterPro:   IPR013340 [H]

Pfam domain/function: PF04208 MtrA [H]

EC number: =2.1.1.86 [H]

Molecular weight: Translated: 27104; Mature: 27104

Theoretical pI: Translated: 3.85; Mature: 3.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVPEKAEPAEGWPVVEGDYVVGDPEAPVHVVTLGSHIEEDILKAAGEDKVAIAGPCKT
CCCCCCCCCCCCCCCEECCCEEECCCCCCEEEEEECHHHHHHHHHHCCCCCEEEECCCCC
ENIGIEKVIANVIANPNIRFGVLCGAEVTGHLTGQCFKAMYENGVDPDSGEIIGAEGAIP
CCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCH
YLENIPEEAVERYRDQIVELVDLIDVEDVDEIVKAIEECVEKDPGAYEEGPMTISLEEEE
HHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHH
EEELAEVAGMPVSAETVTVEYRINDVRVGVKSIGAMQRYMAGYLSGRTMGLLIGIISGMI
HHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FLFLPMVVLGGV
HHHHHHHHHCCC
>Mature Secondary Structure
MLEVPEKAEPAEGWPVVEGDYVVGDPEAPVHVVTLGSHIEEDILKAAGEDKVAIAGPCKT
CCCCCCCCCCCCCCCEECCCEEECCCCCCEEEEEECHHHHHHHHHHCCCCCEEEECCCCC
ENIGIEKVIANVIANPNIRFGVLCGAEVTGHLTGQCFKAMYENGVDPDSGEIIGAEGAIP
CCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCH
YLENIPEEAVERYRDQIVELVDLIDVEDVDEIVKAIEECVEKDPGAYEEGPMTISLEEEE
HHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHH
EEELAEVAGMPVSAETVTVEYRINDVRVGVKSIGAMQRYMAGYLSGRTMGLLIGIISGMI
HHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FLFLPMVVLGGV
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9461302; 11930014 [H]