Click here to switch to the map view.

The map label for this gene is amzA

Identifier: 20093986

GI number: 20093986

Start: 511128

End: 511655

Strand: Direct

Name: amzA

Synonym: MK0548

Alternate gene names: 20093986

Gene position: 511128-511655 (Clockwise)

Preceding gene: 20093985

Following gene: 20093987

Centisome position: 30.16

GC content: 55.87

Gene sequence:

>528_bases
TTGAAGTTGTGCCTGGTGGCGTTTGACGGAAGGATCCCCATGCTCAGCAGTATCGTCGATAGGTTCGAGGAACACGTGTC
GGAGTACCTAGGCGAGGTTAAGGTGAAAAAGAAACGCGCGAAACTACCCGAGCATGCGTACTCCAAGGTGAGAGGCCAAT
ACCTAGCGAGGGCCCTCCTCGATACCCTACGTGGCATGAAAGGGGAGTACGACCGCGTTTTAGGGTTGACCTCGGAGGAC
CTCTACGCTCCGGGACTCAACTTCGTCTTCGGTCAAGCTCGATGTCCGGGTAGAGAGGCCGTAGTCTCGGTGGCCCGACT
GCTGGATCCGGATCCGGAGTTGTACCTGGAGCGTGTCGTGAAGGAGCTCACGCACGAGCTCGGACACACCTTCGGGTTGG
GCCACTGCCCGGACCGTAACTGCGTGATGAGCTTCTCGAGTTCACTTCTCGAAGTAGACCGCAAATCACCGAACTTCTGT
CGAAGATGTACCGAATTACTTCAAAGAAACTTGAAACGCGGAGGTTGA

Upstream 100 bases:

>100_bases
ATGATCTCGTTCCGGCGCGGCGGGGACAGGGTCCTCGGCCTGATGGGATTTCTACTGTTGATGGTAGGTATAGCCGTGCT
AACGGGCAGGGTGAGATAGT

Downstream 100 bases:

>100_bases
ACGGGGCCGTAGTCGTGACCATCGAGTACGTAGACAAAGTGGGGCGCAGAGTGGTCGTTCGGAGGGCTAAAAGGTCCGAC
ATCCCGGAAGTTGTGGAGAT

Product: Zn-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKLCLVAFDGRIPMLSSIVDRFEEHVSEYLGEVKVKKKRAKLPEHAYSKVRGQYLARALLDTLRGMKGEYDRVLGLTSED
LYAPGLNFVFGQARCPGREAVVSVARLLDPDPELYLERVVKELTHELGHTFGLGHCPDRNCVMSFSSSLLEVDRKSPNFC
RRCTELLQRNLKRGG

Sequences:

>Translated_175_residues
MKLCLVAFDGRIPMLSSIVDRFEEHVSEYLGEVKVKKKRAKLPEHAYSKVRGQYLARALLDTLRGMKGEYDRVLGLTSED
LYAPGLNFVFGQARCPGREAVVSVARLLDPDPELYLERVVKELTHELGHTFGLGHCPDRNCVMSFSSSLLEVDRKSPNFC
RRCTELLQRNLKRGG
>Mature_175_residues
MKLCLVAFDGRIPMLSSIVDRFEEHVSEYLGEVKVKKKRAKLPEHAYSKVRGQYLARALLDTLRGMKGEYDRVLGLTSED
LYAPGLNFVFGQARCPGREAVVSVARLLDPDPELYLERVVKELTHELGHTFGLGHCPDRNCVMSFSSSLLEVDRKSPNFC
RRCTELLQRNLKRGG

Specific function: Probable zinc metalloprotease

COG id: COG1913

COG function: function code R; Predicted Zn-dependent proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M54 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AMZA_METKA (Q8TXW1)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613833.1
- PDB:   2X7M
- PDBsum:   2X7M
- ProteinModelPortal:   Q8TXW1
- SMR:   Q8TXW1
- MEROPS:   M54.001
- GeneID:   1476649
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0548
- NMPDR:   fig|190192.1.peg.546
- HOGENOM:   HBG508786
- OMA:   DIKSWMY
- BioCyc:   MKAN190192:MK0548-MONOMER
- HAMAP:   MF_01842
- InterPro:   IPR012962
- InterPro:   IPR012091
- PIRSF:   PIRSF005785

Pfam domain/function: PF07998 Peptidase_M54

EC number: NA

Molecular weight: Translated: 19827; Mature: 19827

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLCLVAFDGRIPMLSSIVDRFEEHVSEYLGEVKVKKKRAKLPEHAYSKVRGQYLARALL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DTLRGMKGEYDRVLGLTSEDLYAPGLNFVFGQARCPGREAVVSVARLLDPDPELYLERVV
HHHHCCCCCHHHHHCCCCCHHHCCCCHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
KELTHELGHTFGLGHCPDRNCVMSFSSSLLEVDRKSPNFCRRCTELLQRNLKRGG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLCLVAFDGRIPMLSSIVDRFEEHVSEYLGEVKVKKKRAKLPEHAYSKVRGQYLARALL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DTLRGMKGEYDRVLGLTSEDLYAPGLNFVFGQARCPGREAVVSVARLLDPDPELYLERVV
HHHHCCCCCHHHHHCCCCCHHHCCCCHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
KELTHELGHTFGLGHCPDRNCVMSFSSSLLEVDRKSPNFCRRCTELLQRNLKRGG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014