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The map label for this gene is 20093963

Identifier: 20093963

GI number: 20093963

Start: 488504

End: 489094

Strand: Direct

Name: 20093963

Synonym: MK0525

Alternate gene names: NA

Gene position: 488504-489094 (Clockwise)

Preceding gene: 20093960

Following gene: 20093964

Centisome position: 28.82

GC content: 52.96

Gene sequence:

>591_bases
GTGCGCAGCGTGTCGGTAGGCGAGGTAGCCAGACGTGACGTGATCACGGGCAGTCCCACGGAAACCGCAGTGGAGATCGC
CTACAAGATGCGGGAACATGGCATCGGCAGCGTGGTCATAGTGAACGAGAAAGACGAGCCCATTGGCATCATCACGGAGC
GCGATCTCGTGATCAAGGTGGTATCACAGGGTAAGAACCCCGACGAGGTGATAGCGCGGGATATCATGTCTCAACCGGTG
ATTACCGTCGAGGAGGACATGGAGGTCAACGAAGCCGTGAAACTGATGGTAGACAAGGGGATTCGAAGGCTTCCGATCGT
AGACGATAATGGTAAACTGATAGGTATCGTAACGATGCAGGACATTCTCCAGGTTGAGCCCTACTTAGTAGCTACCATAG
AGGAGGAGATGAAGAAATTCCAGGAAGAGCTCGAGGAACTAGAGGAAGTGTCAGAGATTATTGAAGGAGTTTGCGACCTC
TGTGAGACCTACTCGGAAGAGCTCCGATTCGTCGACGGAGTGTGGGTTTGTCCTGAGTGTTACGAGGACATTTTAGGCAG
GGAGATCGAAGACAGGGAACTCGAGGAGTGA

Upstream 100 bases:

>100_bases
ACGAGAGTTGAGGTAGGACTCTACAGTGGTCGCAAGCGTGACCGGTGGAGTTATTACAACGGCGGAAGACGCGCGTTTCC
GGCGGGGGTGCCCTCTATTG

Downstream 100 bases:

>100_bases
TCACCCGTGCTGACACGTCGTTCCGGTTTGCCAGACACCTCCGTCATGAGGTTAGCCACCACGAACGTCGTATCGATGCC
ACCTACCGCCACAGTGAAAA

Product: CBS-domain-containing protein

Products: NA

Alternate protein names: OrfX

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRSVSVGEVARRDVITGSPTETAVEIAYKMREHGIGSVVIVNEKDEPIGIITERDLVIKVVSQGKNPDEVIARDIMSQPV
ITVEEDMEVNEAVKLMVDKGIRRLPIVDDNGKLIGIVTMQDILQVEPYLVATIEEEMKKFQEELEELEEVSEIIEGVCDL
CETYSEELRFVDGVWVCPECYEDILGREIEDRELEE

Sequences:

>Translated_196_residues
MRSVSVGEVARRDVITGSPTETAVEIAYKMREHGIGSVVIVNEKDEPIGIITERDLVIKVVSQGKNPDEVIARDIMSQPV
ITVEEDMEVNEAVKLMVDKGIRRLPIVDDNGKLIGIVTMQDILQVEPYLVATIEEEMKKFQEELEELEEVSEIIEGVCDL
CETYSEELRFVDGVWVCPECYEDILGREIEDRELEE
>Mature_196_residues
MRSVSVGEVARRDVITGSPTETAVEIAYKMREHGIGSVVIVNEKDEPIGIITERDLVIKVVSQGKNPDEVIARDIMSQPV
ITVEEDMEVNEAVKLMVDKGIRRLPIVDDNGKLIGIVTMQDILQVEPYLVATIEEEMKKFQEELEELEEVSEIIEGVCDL
CETYSEELRFVDGVWVCPECYEDILGREIEDRELEE

Specific function: Unknown

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y525_METKA (P50100)

Other databases:

- EMBL:   AE009439
- EMBL:   U31567
- RefSeq:   NP_613810.1
- ProteinModelPortal:   P50100
- SMR:   P50100
- GeneID:   1476626
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0525
- NMPDR:   fig|190192.1.peg.523
- HOGENOM:   HBG739441
- OMA:   IDMNREA
- BioCyc:   MKAN190192:MK0525-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR000644
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00116

Pfam domain/function: PF00571 CBS

EC number: NA

Molecular weight: Translated: 22198; Mature: 22198

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVSVGEVARRDVITGSPTETAVEIAYKMREHGIGSVVIVNEKDEPIGIITERDLVIKV
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHH
VSQGKNPDEVIARDIMSQPVITVEEDMEVNEAVKLMVDKGIRRLPIVDDNGKLIGIVTMQ
HHCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCEECCCCCEEEEEEHH
DILQVEPYLVATIEEEMKKFQEELEELEEVSEIIEGVCDLCETYSEELRFVDGVWVCPEC
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHH
YEDILGREIEDRELEE
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRSVSVGEVARRDVITGSPTETAVEIAYKMREHGIGSVVIVNEKDEPIGIITERDLVIKV
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHH
VSQGKNPDEVIARDIMSQPVITVEEDMEVNEAVKLMVDKGIRRLPIVDDNGKLIGIVTMQ
HHCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCEECCCCCEEEEEEHH
DILQVEPYLVATIEEEMKKFQEELEELEEVSEIIEGVCDLCETYSEELRFVDGVWVCPEC
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHH
YEDILGREIEDRELEE
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014; 8522533