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The map label for this gene is mshA [H]

Identifier: 197118172

GI number: 197118172

Start: 2062567

End: 2063718

Strand: Direct

Name: mshA [H]

Synonym: Gbem_1787

Alternate gene names: 197118172

Gene position: 2062567-2063718 (Clockwise)

Preceding gene: 197118171

Following gene: 197118173

Centisome position: 44.69

GC content: 64.24

Gene sequence:

>1152_bases
ATGGATCTGATCATCCCCAAGGTAATGCACGTCATCCTCTCGCTCGATGCAGGCGGAGGCGCCGAGAGGCTGGTCTATGA
CCTCGTGCGTGACGCCGTTTTTTCCCCCGCCCCCCCGGTCGTCTGCTGTCTCTACCATCCCGGCAAACTGGGAGTCCTGC
TGCAACAGGAGGGTTTTCGGGTGTACTCGCCAGCCACCAAACCGGGTGGGCTCCAGTGGTCCCTCGTCCCCTGGCTCGCC
CGGATCATCCGAAAGGAAGGTGTCGATGTGGTGCACGCCCACCAGTACACCCCCATGTTCTACAGCGTCCCGGCGGCGCT
CGCGGCGGGCCGCAAGCGGGTCATCTACACCGAACACGGCAGGCTCTACCCGGACCTTCCCAAGTGGAAACGGCGCCTTT
GCAACCCGCTTTTATCGTGGGGGATCGACCAGATCGTCTCCATCTCGGACGGCACCAAGGAGGCGATGGTGGCGGTCGAC
AACTTCGCCGGGGATCGCATCGCCGTGGTGCACAACGGCGTCCTCTTCGCCAAGCCCGGCTCCGATTTCGACCCCGCAGA
AAAGAGGCGCTCGCTCGGCATCCCCCCCTCGCACCGGATCATCGGGACCGCGGCGCGGCTGGAGCGGATCAAGAACCTCC
CCATGATGCTGCGCGGTTTCCAGCGCGTGCTGGAAAAGATGCCCGATACCTCGCTCCTGATCGCGGGGAGGGGGTCGCGC
GAAAGGGCCCTGAAGCAGTACGCCCAGGAACTCGGCATAGCGGATAAGGTGCGTTTCCTCGGGCTGCGGGACGATCTCCC
CGAGATCTACCCGCTTTTCGAGCTCTTCCTGCTCACCTCCTTTTCGGAAGGGATCTCCGTCACCCTGCTGGAGGCGATGT
CTCACGGCGTGGCGCCCATCGCCACCCGGGTGGGGGGCAACCCGGAGGTGGTCCTCGAGGGCGAGACCGGCCTCCTGGTG
GGGGATGACGATTACATCGAGCTCGGCGAGAAGATCCTGGAGCTCATGGCGGTTCCTGAGCGCGCCAGGCGCATGGGGGA
GGCCGCCCACGGCTGGGTCGGGAATCATTTTTCCTTCGAAAAGATGGTCCAGGACTATCTGCGGCTCTACCGGGGAGCCG
AGGCTAACCCCGATGATCAGGTAAGGGAATAG

Upstream 100 bases:

>100_bases
GGCCTACTATACCTCCCTTACCGAGACGCTCGGCTACTACGCCAAGCGGGCCCTGGAGCGTACGGGGCTGTACCATGCCC
TCTAGGAGAAGGCCGCAGCT

Downstream 100 bases:

>100_bases
GTGGAACATGCGTGAGATAGTCCTTTACATCCTGATCGCAATGTCGGCTCCGGCTGTCCTGCGTCGTCCCTTCTTGGGCG
TGGTGATCTACCTCGGCGCC

Product: group glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDLIIPKVMHVILSLDAGGGAERLVYDLVRDAVFSPAPPVVCCLYHPGKLGVLLQQEGFRVYSPATKPGGLQWSLVPWLA
RIIRKEGVDVVHAHQYTPMFYSVPAALAAGRKRVIYTEHGRLYPDLPKWKRRLCNPLLSWGIDQIVSISDGTKEAMVAVD
NFAGDRIAVVHNGVLFAKPGSDFDPAEKRRSLGIPPSHRIIGTAARLERIKNLPMMLRGFQRVLEKMPDTSLLIAGRGSR
ERALKQYAQELGIADKVRFLGLRDDLPEIYPLFELFLLTSFSEGISVTLLEAMSHGVAPIATRVGGNPEVVLEGETGLLV
GDDDYIELGEKILELMAVPERARRMGEAAHGWVGNHFSFEKMVQDYLRLYRGAEANPDDQVRE

Sequences:

>Translated_383_residues
MDLIIPKVMHVILSLDAGGGAERLVYDLVRDAVFSPAPPVVCCLYHPGKLGVLLQQEGFRVYSPATKPGGLQWSLVPWLA
RIIRKEGVDVVHAHQYTPMFYSVPAALAAGRKRVIYTEHGRLYPDLPKWKRRLCNPLLSWGIDQIVSISDGTKEAMVAVD
NFAGDRIAVVHNGVLFAKPGSDFDPAEKRRSLGIPPSHRIIGTAARLERIKNLPMMLRGFQRVLEKMPDTSLLIAGRGSR
ERALKQYAQELGIADKVRFLGLRDDLPEIYPLFELFLLTSFSEGISVTLLEAMSHGVAPIATRVGGNPEVVLEGETGLLV
GDDDYIELGEKILELMAVPERARRMGEAAHGWVGNHFSFEKMVQDYLRLYRGAEANPDDQVRE
>Mature_383_residues
MDLIIPKVMHVILSLDAGGGAERLVYDLVRDAVFSPAPPVVCCLYHPGKLGVLLQQEGFRVYSPATKPGGLQWSLVPWLA
RIIRKEGVDVVHAHQYTPMFYSVPAALAAGRKRVIYTEHGRLYPDLPKWKRRLCNPLLSWGIDQIVSISDGTKEAMVAVD
NFAGDRIAVVHNGVLFAKPGSDFDPAEKRRSLGIPPSHRIIGTAARLERIKNLPMMLRGFQRVLEKMPDTSLLIAGRGSR
ERALKQYAQELGIADKVRFLGLRDDLPEIYPLFELFLLTSFSEGISVTLLEAMSHGVAPIATRVGGNPEVVLEGETGLLV
GDDDYIELGEKILELMAVPERARRMGEAAHGWVGNHFSFEKMVQDYLRLYRGAEANPDDQVRE

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=309, Percent_Identity=23.9482200647249, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532709, Length=309, Percent_Identity=21.6828478964401, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI9755344, Length=312, Percent_Identity=23.7179487179487, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 42539; Mature: 42539

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIIPKVMHVILSLDAGGGAERLVYDLVRDAVFSPAPPVVCCLYHPGKLGVLLQQEGFR
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCE
VYSPATKPGGLQWSLVPWLARIIRKEGVDVVHAHQYTPMFYSVPAALAAGRKRVIYTEHG
EECCCCCCCCCEEEHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCC
RLYPDLPKWKRRLCNPLLSWGIDQIVSISDGTKEAMVAVDNFAGDRIAVVHNGVLFAKPG
CCCCCCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHEEEECCCCCEEEEEECCEEEECCC
SDFDPAEKRRSLGIPPSHRIIGTAARLERIKNLPMMLRGFQRVLEKMPDTSLLIAGRGSR
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCH
ERALKQYAQELGIADKVRFLGLRDDLPEIYPLFELFLLTSFSEGISVTLLEAMSHGVAPI
HHHHHHHHHHCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
ATRVGGNPEVVLEGETGLLVGDDDYIELGEKILELMAVPERARRMGEAAHGWVGNHFSFE
HHHCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHH
KMVQDYLRLYRGAEANPDDQVRE
HHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MDLIIPKVMHVILSLDAGGGAERLVYDLVRDAVFSPAPPVVCCLYHPGKLGVLLQQEGFR
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCE
VYSPATKPGGLQWSLVPWLARIIRKEGVDVVHAHQYTPMFYSVPAALAAGRKRVIYTEHG
EECCCCCCCCCEEEHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCC
RLYPDLPKWKRRLCNPLLSWGIDQIVSISDGTKEAMVAVDNFAGDRIAVVHNGVLFAKPG
CCCCCCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHEEEECCCCCEEEEEECCEEEECCC
SDFDPAEKRRSLGIPPSHRIIGTAARLERIKNLPMMLRGFQRVLEKMPDTSLLIAGRGSR
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCH
ERALKQYAQELGIADKVRFLGLRDDLPEIYPLFELFLLTSFSEGISVTLLEAMSHGVAPI
HHHHHHHHHHCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
ATRVGGNPEVVLEGETGLLVGDDDYIELGEKILELMAVPERARRMGEAAHGWVGNHFSFE
HHHCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHH
KMVQDYLRLYRGAEANPDDQVRE
HHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA