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The map label for this gene is mtnN [H]

Identifier: 197117267

GI number: 197117267

Start: 1030802

End: 1031569

Strand: Reverse

Name: mtnN [H]

Synonym: Gbem_0877

Alternate gene names: 197117267

Gene position: 1031569-1030802 (Counterclockwise)

Preceding gene: 197117272

Following gene: 197117226

Centisome position: 22.35

GC content: 65.36

Gene sequence:

>768_bases
ATGAAGACAGAGTGCCTCGGGGCGGTGGCCGCCATGCCCCAGGAGATAGCCCCGCTTTTGCGACGGGTGCGGCGGTTCCA
GAAGGAAAAGATCTCCGGGTTCAACCTGTACCGCTTCGACTGCGGCAGTACCCGCGTCGCCCTGATCGAATCCGGGATGG
GGCCCGACCACGCGGCTCTTGCCACGGCAACCCTGATCCGGAGCGCCTCGCCGCATGTGATCCTCAACTTCGGGTTCTGC
GGCGGCGTGCTCCCCGGCCTAACCGTAGGCGACCTGGTGCTGGCCGAGCGGGTCTTCGCGCTTGCCGGGGGGAGACTGAG
CGAGGTGCTCACACCTCCTCTGCCGCTGACCTCCCCGATCCTGGAAAGCTGCCGCAAACACGGGCTCTCTTCCCGGCCCG
GCTCCTTCATCACCGCCACCGGTGTGGTGAACAAGCGCGCGCTCGCGCAGACGCTGGAGGGATCGATTCACGAACCGGTG
CTGGAAATGGAGAGTGCTGCGGTGTTCCGGGAGGCCGAAAAAGCCGGAATCGAAGCAGTGGCGCTCAGAGGGGTGAGCGA
CCCGGCAGAGGAAGAACTTGGCTTCGACATCGCCGAGATCTGCGACTCGGAGCTGAACCTGAGCCCGTGGCGGCTCGTGC
TCACCCTGGCCAAGAGACCTTCGCTGGTACCGCAGTTCATCCGGCTGGCGCGGAACTCCAAGGTAGCGGGGGCAAACCTG
GCGCTCGGGGTGGAGCTGGCGCTTTTGGTGCTTAGCGAAACGCAGTAA

Upstream 100 bases:

>100_bases
ATGTCGGCGCATCCAGTTTGTCAAGTTAACCCTCTTTGACATTGCGGCAAAAGCCCCGCTCTGTTAAAGTGCGCGAACCA
AACTACAGGAGCGCCTGGCC

Downstream 100 bases:

>100_bases
ACAAAAGGGTCAATCGAAGCTTTCGGAGAAGCGTGCCGCTATCTCTCCCTTCAAGTAGGCGTCCGCTTCGGCCGCGGTCG
AAAAGGAAAGGGCGCGCGAG

Product: nucleoside phosphorylase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKTECLGAVAAMPQEIAPLLRRVRRFQKEKISGFNLYRFDCGSTRVALIESGMGPDHAALATATLIRSASPHVILNFGFC
GGVLPGLTVGDLVLAERVFALAGGRLSEVLTPPLPLTSPILESCRKHGLSSRPGSFITATGVVNKRALAQTLEGSIHEPV
LEMESAAVFREAEKAGIEAVALRGVSDPAEEELGFDIAEICDSELNLSPWRLVLTLAKRPSLVPQFIRLARNSKVAGANL
ALGVELALLVLSETQ

Sequences:

>Translated_255_residues
MKTECLGAVAAMPQEIAPLLRRVRRFQKEKISGFNLYRFDCGSTRVALIESGMGPDHAALATATLIRSASPHVILNFGFC
GGVLPGLTVGDLVLAERVFALAGGRLSEVLTPPLPLTSPILESCRKHGLSSRPGSFITATGVVNKRALAQTLEGSIHEPV
LEMESAAVFREAEKAGIEAVALRGVSDPAEEELGFDIAEICDSELNLSPWRLVLTLAKRPSLVPQFIRLARNSKVAGANL
ALGVELALLVLSETQ
>Mature_255_residues
MKTECLGAVAAMPQEIAPLLRRVRRFQKEKISGFNLYRFDCGSTRVALIESGMGPDHAALATATLIRSASPHVILNFGFC
GGVLPGLTVGDLVLAERVFALAGGRLSEVLTPPLPLTSPILESCRKHGLSSRPGSFITATGVVNKRALAQTLEGSIHEPV
LEMESAAVFREAEKAGIEAVALRGVSDPAEEELGFDIAEICDSELNLSPWRLVLTLAKRPSLVPQFIRLARNSKVAGANL
ALGVELALLVLSETQ

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27175; Mature: 27175

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTECLGAVAAMPQEIAPLLRRVRRFQKEKISGFNLYRFDCGSTRVALIESGMGPDHAAL
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCHHHH
ATATLIRSASPHVILNFGFCGGVLPGLTVGDLVLAERVFALAGGRLSEVLTPPLPLTSPI
HHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHH
LESCRKHGLSSRPGSFITATGVVNKRALAQTLEGSIHEPVLEMESAAVFREAEKAGIEAV
HHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHE
ALRGVSDPAEEELGFDIAEICDSELNLSPWRLVLTLAKRPSLVPQFIRLARNSKVAGANL
EECCCCCCHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHH
ALGVELALLVLSETQ
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTECLGAVAAMPQEIAPLLRRVRRFQKEKISGFNLYRFDCGSTRVALIESGMGPDHAAL
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCHHHH
ATATLIRSASPHVILNFGFCGGVLPGLTVGDLVLAERVFALAGGRLSEVLTPPLPLTSPI
HHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHH
LESCRKHGLSSRPGSFITATGVVNKRALAQTLEGSIHEPVLEMESAAVFREAEKAGIEAV
HHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHE
ALRGVSDPAEEELGFDIAEICDSELNLSPWRLVLTLAKRPSLVPQFIRLARNSKVAGANL
EECCCCCCHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHH
ALGVELALLVLSETQ
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA