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The map label for this gene is engA

Identifier: 197117132

GI number: 197117132

Start: 869832

End: 871154

Strand: Direct

Name: engA

Synonym: Gbem_0737

Alternate gene names: 197117132

Gene position: 869832-871154 (Clockwise)

Preceding gene: 197117130

Following gene: 197117133

Centisome position: 18.85

GC content: 62.13

Gene sequence:

>1323_bases
ATGAAACCAATTATTGCCATCGTCGGGCGCCCGAACGTCGGGAAGTCCACCCTCTTCAACAGGCTGGTCGGGCGCCGCAA
GGCGATGGTCGACGATATGCCCGGGGTGACCCGGGACCGAAACTACGCGGAGGTGAACCGCTTCGACGTCCCCTTCATCC
TGGTGGATACCGGCGGCTTCGAGCCGGAGACCTCCGACCGGCTTTTGCAGCAGATGAGGGAGCAGTCCCGCTTCGCCATG
GACGAGGCGGACCTGATCCTCTTCATCATGGACGCCCGCGGGGGGCTGACGCCTGCCGACCGTGACGTCGTGGACATGCT
CAGGCGCATCAACAAGCCGGTCTTCTACATCATCAACAAGGTGGACGGGGAAAAGCAGGAGGCCGAAGCGGGTGATTTCT
ATTCGCTTGGGGTCGATCACATCCACACCATCTCCGCCGAGCACAACCGCGGCGTGGGCGACCTCATGGACGAGGTGCTG
GCCGCCATCCCCTACGACCGGGAAAAAGAGCTGGACGAGGAGATCACCAGGATCGCGGTGGTCGGGCGCCCGAACGTCGG
CAAATCCACCCTGGTGAACCGGCTTTTGGGGTACGAGCGCGTGGTGGCGAATCCCACCGCCGGTACCACGAGGGACGCGG
TCGACACCCGCTTCACGGTGAACAAGAAGCCCTACCTCTTGATCGACACGGCGGGGATCCGGAGGAAAGGGAAGACGGTC
CAGAAGGTGGAGAAGTACTCGGTCATGGACGCGCTGCGCTCCATCGAGCGCGCCGACGTGGTCCTCATCGTGCTGAACGC
GGAAGAAGGTGTGACCGAGCAGGACTCGAAGATCGCGGGATACGCCTACGAGGCGGGGCGCGGCTGCATCTTCGTGGTGA
ACAAGTGGGACACCCTGGCAAAGGACAACTCCAGCATCGCCAAGTTCACCGAGGAGATCCGGCGCAACTTCAAATACCTC
CCCTTCGCGCCGATCCTGTTCGTCTCGGCGGAAACCGGGCAGAGGACCGGCAAGATCATCGCCGAGGTGGACCAGGTGAT
GGAGCAGTACTGCAAGCGCGTCACCACCGGCGAGTTGAACCGGGTCTTCACCCAGGCGGTTGACGAGAACCACGCGCCCC
TTTCCGCGGGGAGGCGGGTGAAGTTCTACTTCGCGACGCAGGTGGCGGTAAAGCCCCCCTCTTTCGTCGTCTTCACCAAC
TGCCCTGAGGGGATCCACTTCTCCTATGAGCGCTATATCATGAACCGGTTTAGAGAGGCCTTCGGTTTCAACGGCACTCC
GCTGAAGCTGATTTTCCGCGGCAGGGACAAGAAAGACGCCTAA

Upstream 100 bases:

>100_bases
TGCAAAATGTTACAGATAGCGGTTAGTTGTCAAATACATTAAAACGGAAAGTTGCGCCTTTTAACCGGTTTGAAGGCGAC
GTCTTTCCAGCTGGAACCAA

Downstream 100 bases:

>100_bases
ATCATTCTTGCCTTGCCAGATACGATGGTTTAATATATGCCAATTTTTAACCCACCCCCCATGAGAGAGCGGCATCCATG
AGTCTTGTCGGCAATTTGGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKPIIAIVGRPNVGKSTLFNRLVGRRKAMVDDMPGVTRDRNYAEVNRFDVPFILVDTGGFEPETSDRLLQQMREQSRFAM
DEADLILFIMDARGGLTPADRDVVDMLRRINKPVFYIINKVDGEKQEAEAGDFYSLGVDHIHTISAEHNRGVGDLMDEVL
AAIPYDREKELDEEITRIAVVGRPNVGKSTLVNRLLGYERVVANPTAGTTRDAVDTRFTVNKKPYLLIDTAGIRRKGKTV
QKVEKYSVMDALRSIERADVVLIVLNAEEGVTEQDSKIAGYAYEAGRGCIFVVNKWDTLAKDNSSIAKFTEEIRRNFKYL
PFAPILFVSAETGQRTGKIIAEVDQVMEQYCKRVTTGELNRVFTQAVDENHAPLSAGRRVKFYFATQVAVKPPSFVVFTN
CPEGIHFSYERYIMNRFREAFGFNGTPLKLIFRGRDKKDA

Sequences:

>Translated_440_residues
MKPIIAIVGRPNVGKSTLFNRLVGRRKAMVDDMPGVTRDRNYAEVNRFDVPFILVDTGGFEPETSDRLLQQMREQSRFAM
DEADLILFIMDARGGLTPADRDVVDMLRRINKPVFYIINKVDGEKQEAEAGDFYSLGVDHIHTISAEHNRGVGDLMDEVL
AAIPYDREKELDEEITRIAVVGRPNVGKSTLVNRLLGYERVVANPTAGTTRDAVDTRFTVNKKPYLLIDTAGIRRKGKTV
QKVEKYSVMDALRSIERADVVLIVLNAEEGVTEQDSKIAGYAYEAGRGCIFVVNKWDTLAKDNSSIAKFTEEIRRNFKYL
PFAPILFVSAETGQRTGKIIAEVDQVMEQYCKRVTTGELNRVFTQAVDENHAPLSAGRRVKFYFATQVAVKPPSFVVFTN
CPEGIHFSYERYIMNRFREAFGFNGTPLKLIFRGRDKKDA
>Mature_440_residues
MKPIIAIVGRPNVGKSTLFNRLVGRRKAMVDDMPGVTRDRNYAEVNRFDVPFILVDTGGFEPETSDRLLQQMREQSRFAM
DEADLILFIMDARGGLTPADRDVVDMLRRINKPVFYIINKVDGEKQEAEAGDFYSLGVDHIHTISAEHNRGVGDLMDEVL
AAIPYDREKELDEEITRIAVVGRPNVGKSTLVNRLLGYERVVANPTAGTTRDAVDTRFTVNKKPYLLIDTAGIRRKGKTV
QKVEKYSVMDALRSIERADVVLIVLNAEEGVTEQDSKIAGYAYEAGRGCIFVVNKWDTLAKDNSSIAKFTEEIRRNFKYL
PFAPILFVSAETGQRTGKIIAEVDQVMEQYCKRVTTGELNRVFTQAVDENHAPLSAGRRVKFYFATQVAVKPPSFVVFTN
CPEGIHFSYERYIMNRFREAFGFNGTPLKLIFRGRDKKDA

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=461, Percent_Identity=40.997830802603, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI2367268, Length=136, Percent_Identity=36.0294117647059, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=125, Percent_Identity=33.6, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=184, Percent_Identity=28.804347826087, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_GEOBB (B5EE25)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137559.1
- ProteinModelPortal:   B5EE25
- SMR:   B5EE25
- GeneID:   6783570
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0737
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49684; Mature: 49684

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIIAIVGRPNVGKSTLFNRLVGRRKAMVDDMPGVTRDRNYAEVNRFDVPFILVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEECCCC
EPETSDRLLQQMREQSRFAMDEADLILFIMDARGGLTPADRDVVDMLRRINKPVFYIINK
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEC
VDGEKQEAEAGDFYSLGVDHIHTISAEHNRGVGDLMDEVLAAIPYDREKELDEEITRIAV
CCCCHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHEEEE
VGRPNVGKSTLVNRLLGYERVVANPTAGTTRDAVDTRFTVNKKPYLLIDTAGIRRKGKTV
ECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHH
QKVEKYSVMDALRSIERADVVLIVLNAEEGVTEQDSKIAGYAYEAGRGCIFVVNKWDTLA
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHH
KDNSSIAKFTEEIRRNFKYLPFAPILFVSAETGQRTGKIIAEVDQVMEQYCKRVTTGELN
CCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
RVFTQAVDENHAPLSAGRRVKFYFATQVAVKPPSFVVFTNCPEGIHFSYERYIMNRFREA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
FGFNGTPLKLIFRGRDKKDA
HCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKPIIAIVGRPNVGKSTLFNRLVGRRKAMVDDMPGVTRDRNYAEVNRFDVPFILVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEECCCC
EPETSDRLLQQMREQSRFAMDEADLILFIMDARGGLTPADRDVVDMLRRINKPVFYIINK
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEC
VDGEKQEAEAGDFYSLGVDHIHTISAEHNRGVGDLMDEVLAAIPYDREKELDEEITRIAV
CCCCHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHEEEE
VGRPNVGKSTLVNRLLGYERVVANPTAGTTRDAVDTRFTVNKKPYLLIDTAGIRRKGKTV
ECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHH
QKVEKYSVMDALRSIERADVVLIVLNAEEGVTEQDSKIAGYAYEAGRGCIFVVNKWDTLA
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHH
KDNSSIAKFTEEIRRNFKYLPFAPILFVSAETGQRTGKIIAEVDQVMEQYCKRVTTGELN
CCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
RVFTQAVDENHAPLSAGRRVKFYFATQVAVKPPSFVVFTNCPEGIHFSYERYIMNRFREA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
FGFNGTPLKLIFRGRDKKDA
HCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA