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The map label for this gene is lolA [H]

Identifier: 197117017

GI number: 197117017

Start: 741031

End: 741741

Strand: Reverse

Name: lolA [H]

Synonym: Gbem_0620

Alternate gene names: 197117017

Gene position: 741741-741031 (Counterclockwise)

Preceding gene: 197117018

Following gene: 197117016

Centisome position: 16.07

GC content: 57.67

Gene sequence:

>711_bases
ATGAAATTGATCAGAGTTTCGATGCTAGTCATGGCGCTGGTTGCGCTTTCCGCAACGATGTCGTTTGCAGCCGAACTTTC
GCAGGTGGTCCGGACCCTGGAGCAGGGTTACGCTGGCCTCAACGACCTGCAGGCCGATTTCAGCCAGCGCAGCCTCATCA
GGGCGATGCGTCGCGAGGAGAAGGGTGGGGGCGAGCTTCTGATCAAGAAGGGGGGCGGAAAAGACTCCATGTTCCGCTTC
AACTACACCAAGCCCAAGCAGCAGATCGTCTCCAACGGCAAGACCGTCTGGTATTACATCCCGGACCAGAAACAGGTGAT
GATCATGGACCTGGCCCATCTTTTCGAGGCGGGGAACGGCATCGCCATGAACTACCTGGCAGGACTGGGGCAGGTGTCGA
GGGACTTCAAGATCAGCTTTGCCGACCAGCAGCGCGACAAAAACGGGAACTACCAACTGGAGCTGATCCCCAACAGGAAA
AGCCCGGCCATGGCGAAGCTCATCCTGGTTATCGACGGCAAGGCGGTGGAAACCTTCATCTCCAAGGGGCGCCCCGGGAC
TCCGTTCCCCGTCGTCTCCTCCACCGTAGTCGACCAAGCGGGAAACAGCACCAGAATGGATTTCAGCGGCATCAAGACCA
ACCGCGGGATCTCCGACAGCAAGTTCAGCTTCAAGGTCCCCGCGGGGGTTGAAATCGTAAAAAACAGATAA

Upstream 100 bases:

>100_bases
CGGGTTGTGTGTCAGAATGCCCGGTCAAATCGCTGCCACAGCAACACACAGAAAGGTCCCGAGCCCTTGCCCGAGACCTT
CACTACTTTCAGAGGTCGAC

Downstream 100 bases:

>100_bases
AGATTGAAAAAACAGATAGAGATAGAGATAAAGATTGAGGAAAGGCTAAAAAACTCAGATAGAGATAGAGATAAAGATAG
AGGAAAGGCCTAAAAAGCAG

Product: outer membrane lipoprotein carrier/sorting protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKLIRVSMLVMALVALSATMSFAAELSQVVRTLEQGYAGLNDLQADFSQRSLIRAMRREEKGGGELLIKKGGGKDSMFRF
NYTKPKQQIVSNGKTVWYYIPDQKQVMIMDLAHLFEAGNGIAMNYLAGLGQVSRDFKISFADQQRDKNGNYQLELIPNRK
SPAMAKLILVIDGKAVETFISKGRPGTPFPVVSSTVVDQAGNSTRMDFSGIKTNRGISDSKFSFKVPAGVEIVKNR

Sequences:

>Translated_236_residues
MKLIRVSMLVMALVALSATMSFAAELSQVVRTLEQGYAGLNDLQADFSQRSLIRAMRREEKGGGELLIKKGGGKDSMFRF
NYTKPKQQIVSNGKTVWYYIPDQKQVMIMDLAHLFEAGNGIAMNYLAGLGQVSRDFKISFADQQRDKNGNYQLELIPNRK
SPAMAKLILVIDGKAVETFISKGRPGTPFPVVSSTVVDQAGNSTRMDFSGIKTNRGISDSKFSFKVPAGVEIVKNR
>Mature_236_residues
MKLIRVSMLVMALVALSATMSFAAELSQVVRTLEQGYAGLNDLQADFSQRSLIRAMRREEKGGGELLIKKGGGKDSMFRF
NYTKPKQQIVSNGKTVWYYIPDQKQVMIMDLAHLFEAGNGIAMNYLAGLGQVSRDFKISFADQQRDKNGNYQLELIPNRK
SPAMAKLILVIDGKAVETFISKGRPGTPFPVVSSTVVDQAGNSTRMDFSGIKTNRGISDSKFSFKVPAGVEIVKNR

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 26067; Mature: 26067

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIRVSMLVMALVALSATMSFAAELSQVVRTLEQGYAGLNDLQADFSQRSLIRAMRREE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
KGGGELLIKKGGGKDSMFRFNYTKPKQQIVSNGKTVWYYIPDQKQVMIMDLAHLFEAGNG
CCCCEEEEEECCCCCCEEEECCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCC
IAMNYLAGLGQVSRDFKISFADQQRDKNGNYQLELIPNRKSPAMAKLILVIDGKAVETFI
EEHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHH
SKGRPGTPFPVVSSTVVDQAGNSTRMDFSGIKTNRGISDSKFSFKVPAGVEIVKNR
HCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCEEECCC
>Mature Secondary Structure
MKLIRVSMLVMALVALSATMSFAAELSQVVRTLEQGYAGLNDLQADFSQRSLIRAMRREE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
KGGGELLIKKGGGKDSMFRFNYTKPKQQIVSNGKTVWYYIPDQKQVMIMDLAHLFEAGNG
CCCCEEEEEECCCCCCEEEECCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCC
IAMNYLAGLGQVSRDFKISFADQQRDKNGNYQLELIPNRKSPAMAKLILVIDGKAVETFI
EEHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHH
SKGRPGTPFPVVSSTVVDQAGNSTRMDFSGIKTNRGISDSKFSFKVPAGVEIVKNR
HCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA