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The map label for this gene is murG [H]

Identifier: 197116889

GI number: 197116889

Start: 592922

End: 593998

Strand: Direct

Name: murG [H]

Synonym: Gbem_0491

Alternate gene names: 197116889

Gene position: 592922-593998 (Clockwise)

Preceding gene: 197116888

Following gene: 197116890

Centisome position: 12.85

GC content: 64.07

Gene sequence:

>1077_bases
ATGAGGCTCATCATCGCAGGCGGCGGGACCGGGGGGCATCTCTTCCCGGGGATAGCGGTCGCCGACGAGTTCCTGGCGCG
CAGCCCCGAGAACGAGGTTCTTTTCGTCGGCACCGAGCGCGGTATCGAGGCGCGGCTCCTGCCGAAGCTCGGCTACAAGC
TGGCCCTCATCTCGGCAAGCGGTATGAAGGGGATGGGGACCATCAAGAAGATCATGAGCGCGGGGCGTCTGCTCTACGGC
TATTCGCAGTCGAGAAAGATCCTGAAGGAGTTCCGTCCCGACCTGGTGTTGGGGGTCGGCGGCTACGCCTCGGCACCCAT
TGTCCTCGCGGCGCGCGGCATGGGGATCAGGCGCTTCATCCATGAGCAAAATGCGTTCCCCGGCCTCACCAACAAGGTCC
TAGGGCGCTTCGTGGACGGCGTCTTCATCTCCATGCCCGAAGCAGAGAGCTTCTTTCCCAAGGAGATGACCCAGATGACC
GGGAACCCGATCCGGAAGGAGATCCTCTGGGGGTTCCAGGAGCGGGTGCGGAGCATCGGGGACACCTTCAGCATCCTCGT
CTTCGGAGGGAGCGCCGGCGCCCAGCGGGTCAACAGCGCGCTTTTGGAGGCGCTGCCGCATCTGGAGGGAGTGAAGGGGA
AACTGAGGATCACGCACCAGACCGGCGAGAAGGACGCGGCCCGGGTGCGCGAGGGATATCAGGCCCAGGGGTTCCAGGCC
CAGGTGCTCAGCTTCATCGACGACATGTCCGCGGCCTACGGCGCCGCCGACCTCGTCGTCTGCAGGGCCGGTGCGACAAC
CATCGCCGAGGTCACCGCCTGCGGCAAGGGGTGCATCTTCATCCCCTTCCCGTATGCTGCCGACGACCACCAGAGGAAAA
ACGCCGAGTCGCTGGTGCACAAAAACGCCGGCGTCATGATCCTGGAAGAAGATCTCACCGGCGAGCGGCTGGCGGCGAAG
ATCCTCGAACTGATGGAGCACCCAGCCGAGCTTGCCGAGATAGAGAAGAACGCCCGAGCCCTGGCCCAGTTAGACGCAGC
CCAGGCCATCGTCTCGGCTATGGTGAGTAAAAACTAA

Upstream 100 bases:

>100_bases
CGCTTCCCTTTTTGAGTTACGGCGGTTCGTCGCTCATCATCTCCCTCACCGCGGTGGGGGTCCTCCTTAACGTATCGACC
AGAATGAGGGGGAACCCGGC

Downstream 100 bases:

>100_bases
GGGCGAGATAAAGATAAAGATAAAGATAAAGAAAAGGCTTGAGGGCCTGAGAGTGGTTCGAGACAACGAAGGAAGTGGCT
TTGAGACATTGACGATAGAG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRLIIAGGGTGGHLFPGIAVADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISASGMKGMGTIKKIMSAGRLLYG
YSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGIRRFIHEQNAFPGLTNKVLGRFVDGVFISMPEAESFFPKEMTQMT
GNPIRKEILWGFQERVRSIGDTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGFQA
QVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVHKNAGVMILEEDLTGERLAAK
ILELMEHPAELAEIEKNARALAQLDAAQAIVSAMVSKN

Sequences:

>Translated_358_residues
MRLIIAGGGTGGHLFPGIAVADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISASGMKGMGTIKKIMSAGRLLYG
YSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGIRRFIHEQNAFPGLTNKVLGRFVDGVFISMPEAESFFPKEMTQMT
GNPIRKEILWGFQERVRSIGDTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGFQA
QVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVHKNAGVMILEEDLTGERLAAK
ILELMEHPAELAEIEKNARALAQLDAAQAIVSAMVSKN
>Mature_358_residues
MRLIIAGGGTGGHLFPGIAVADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISASGMKGMGTIKKIMSAGRLLYG
YSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGIRRFIHEQNAFPGLTNKVLGRFVDGVFISMPEAESFFPKEMTQMT
GNPIRKEILWGFQERVRSIGDTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGFQA
QVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVHKNAGVMILEEDLTGERLAAK
ILELMEHPAELAEIEKNARALAQLDAAQAIVSAMVSKN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=36.2359550561798, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38533; Mature: 38533

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIIAGGGTGGHLFPGIAVADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISAS
CEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHCCCEEEEEECC
GMKGMGTIKKIMSAGRLLYGYSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGIRRFI
CCCCHHHHHHHHHCCCEEECCHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCHHHHHH
HEQNAFPGLTNKVLGRFVDGVFISMPEAESFFPKEMTQMTGNPIRKEILWGFQERVRSIG
HHCCCCCCHHHHHHHHHHCCCEEECCCCHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHC
DTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGFQA
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHH
QVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVH
HHHHHHHHHHHHCCCHHEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
KNAGVMILEEDLTGERLAAKILELMEHPAELAEIEKNARALAQLDAAQAIVSAMVSKN
CCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLIIAGGGTGGHLFPGIAVADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISAS
CEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHCCCEEEEEECC
GMKGMGTIKKIMSAGRLLYGYSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGIRRFI
CCCCHHHHHHHHHCCCEEECCHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCHHHHHH
HEQNAFPGLTNKVLGRFVDGVFISMPEAESFFPKEMTQMTGNPIRKEILWGFQERVRSIG
HHCCCCCCHHHHHHHHHHCCCEEECCCCHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHC
DTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGFQA
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHH
QVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVH
HHHHHHHHHHHHCCCHHEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
KNAGVMILEEDLTGERLAAKILELMEHPAELAEIEKNARALAQLDAAQAIVSAMVSKN
CCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA