Click here to switch to the map view.

The map label for this gene is ato-1 [H]

Identifier: 197116866

GI number: 197116866

Start: 563604

End: 565199

Strand: Direct

Name: ato-1 [H]

Synonym: Gbem_0468

Alternate gene names: 197116866

Gene position: 563604-565199 (Clockwise)

Preceding gene: 197116865

Following gene: 308535166

Centisome position: 12.21

GC content: 61.78

Gene sequence:

>1596_bases
ATGTCCCAGTACGGCACACTGCAAGACCGGGTAAAATGCAAACAACTATTGAACAAGGTCATGGCTCCCGAGCAGACTAT
TGAGTTCTTCAAGAACGGGATGAACCTTGGCTGGTCCGGTTTTACTCCGGCTGGTTACCCGAAAGTGGTGCCTATCGCCC
TGGCTGACCATGTTGAGAAGAACAACCTGCAGGGCAAACTGAGATTCAACCTCTTTATCGGCGCTTCCGTCGGCGCCGAG
ACCGAAGACCGTTGGGCGACTCTGGACATGATCGACCGCCGCTGGCCGTACCAGACCGGCAAGAACATCGCAGCAGGCAT
CAACGCCGGCCGCATCCGCATGGGCGACAAGCACCTCTCCCTGTTCGCGCAGGACCTGGGCTACGGCTTCTACACCAAGG
ACTCCGAAAGCGGCAAGCTCGACCTCGCCATCATCGAAGTCTCCGCCATCAAAGAAGACGGCTCCCTGGTTCCGACCTCT
TCCTGCGGCGTCATCCCCGAAATCCTCATGATCTGCGACAAGATCATCGTCGAGGTGAACACCGGACAGCCCTCCTTCGA
AGGGATCCACGACCTCTTGACCCCGCTCACCCCGCCGAACCGCCAGATCCTCGGCATCACCCATGCCGGCGAGAGGATCG
GTTCGACCTCGATCCCCTGCGACCCGAGCAAGATCGTCGCCGTGGTCGAGTCCAAGCTGCGCGACCAGGGGCGTGCCTTT
GCCGAGCAGGACGACACCTCCGAGGCGATCGCAAACCACATCATCGACTTCTTCACCCACGAGGTGAAAGCCGGCCGTCT
GCCGAAGAACCTCCTCCCGATCCAGTCGGGCGTAGGCTCCATCGCCAACGCCGTTATCGGCGGCCTCGCCAAGGGCCCCT
TCTCCAACCTGACCGTCTACACCGAGGTGCTCCAGGACACCATGCTCGACCTGTTCGATTCCGGCAAGCTCGACGCGGCC
TCCTCCTGCTCGCTCTCCCTCTCGGCGACCCCGGGCTTCCCGCGCTTCTTCGAGAACATGGACAAGTACTTCGACAAGAT
CACCCTGCGTCCGCTCTCCATCTCCAACGCTCCTGAGCCGATCCGCAGGCTTGGGTGCATCGCGATGAACACCCCGGTCG
AGATCGACATCTACGCACACGCCAACTCCACCCTGGTCGGCGGTACCCGCATGATCAACGGCCTGGGCGGCTCGGGCGAC
TTCCTCAGGAACGGCTTCCTGAAGATGATGCACACCCCGTCCTCCCGTCCGAGCAAGACCGACCCCAACGGCATCTCCTG
CGTGGTGCCGCACTGCTCGCACATCGACCACACCGAGCACGACCTCGACTGCGTCATCACCGAGCAGGGCCTGGCCGACC
TGCGCGGCATGGCTCCGAAAGAGCGCGCCCGCCGCATCATCGAGAAGTGCGCGCACCCGGACTACAAGCCGCAGCTCACC
GAGTACCTCAACATCGCCGAGAAAGAGTGCCTGGCGAAGAAGGTCGGCCACGAGCCGCAGCTTTGGGACCGCGCCTTCAA
GATGCACCTCAACCTCGAGAAGAACGGCACCATGAAGCTCAAGAACTGGGACGTCAAGATCGACCTCTGCGAGTAA

Upstream 100 bases:

>100_bases
CAGTCAGTCGGCCGGTCGGGCGTCGGTGCCAAACTCTTATAAATTATCAGCTTAGCGGCTGATCGTAGTCGTAGACACCA
AAACAGAACAGGAGGAAGTT

Downstream 100 bases:

>100_bases
TCGCTCCCACCTTGACTGCAGTAAAAAAAGCCCCGCCGGGAATCCGGCGGGGCTTTTTTGTCTCCGTGTCAGGGTCAGCC
GCGGGTGAGCATCTCCTGCC

Product: succinyl:acetate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSQYGTLQDRVKCKQLLNKVMAPEQTIEFFKNGMNLGWSGFTPAGYPKVVPIALADHVEKNNLQGKLRFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDSESGKLDLAIIEVSAIKEDGSLVPTS
SCGVIPEILMICDKIIVEVNTGQPSFEGIHDLLTPLTPPNRQILGITHAGERIGSTSIPCDPSKIVAVVESKLRDQGRAF
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFSNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSATPGFPRFFENMDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKMMHTPSSRPSKTDPNGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGMAPKERARRIIEKCAHPDYKPQLT
EYLNIAEKECLAKKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE

Sequences:

>Translated_531_residues
MSQYGTLQDRVKCKQLLNKVMAPEQTIEFFKNGMNLGWSGFTPAGYPKVVPIALADHVEKNNLQGKLRFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDSESGKLDLAIIEVSAIKEDGSLVPTS
SCGVIPEILMICDKIIVEVNTGQPSFEGIHDLLTPLTPPNRQILGITHAGERIGSTSIPCDPSKIVAVVESKLRDQGRAF
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFSNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSATPGFPRFFENMDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKMMHTPSSRPSKTDPNGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGMAPKERARRIIEKCAHPDYKPQLT
EYLNIAEKECLAKKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE
>Mature_530_residues
SQYGTLQDRVKCKQLLNKVMAPEQTIEFFKNGMNLGWSGFTPAGYPKVVPIALADHVEKNNLQGKLRFNLFIGASVGAET
EDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDSESGKLDLAIIEVSAIKEDGSLVPTSS
CGVIPEILMICDKIIVEVNTGQPSFEGIHDLLTPLTPPNRQILGITHAGERIGSTSIPCDPSKIVAVVESKLRDQGRAFA
EQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFSNLTVYTEVLQDTMLDLFDSGKLDAAS
SCSLSLSATPGFPRFFENMDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDF
LRNGFLKMMHTPSSRPSKTDPNGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGMAPKERARRIIEKCAHPDYKPQLTE
YLNIAEKECLAKKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=502, Percent_Identity=40.8366533864542, Blast_Score=377, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319456, Length=525, Percent_Identity=57.7142857142857, Blast_Score=612, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 58405; Mature: 58273

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQYGTLQDRVKCKQLLNKVMAPEQTIEFFKNGMNLGWSGFTPAGYPKVVPIALADHVEK
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHC
NNLQGKLRFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCEEECCCCCEEEECHHHHH
LFAQDLGYGFYTKDSESGKLDLAIIEVSAIKEDGSLVPTSSCGVIPEILMICDKIIVEVN
HHHHHHCCCEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEEEC
TGQPSFEGIHDLLTPLTPPNRQILGITHAGERIGSTSIPCDPSKIVAVVESKLRDQGRAF
CCCCCHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCHH
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFSNLTVY
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSATPGFPRFFENMDKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKMMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DPNGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGMAPKERARRIIEKCAHPDYKPQLT
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHH
EYLNIAEKECLAKKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEECCEEEEEECC
>Mature Secondary Structure 
SQYGTLQDRVKCKQLLNKVMAPEQTIEFFKNGMNLGWSGFTPAGYPKVVPIALADHVEK
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHC
NNLQGKLRFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCEEECCCCCEEEECHHHHH
LFAQDLGYGFYTKDSESGKLDLAIIEVSAIKEDGSLVPTSSCGVIPEILMICDKIIVEVN
HHHHHHCCCEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEEEC
TGQPSFEGIHDLLTPLTPPNRQILGITHAGERIGSTSIPCDPSKIVAVVESKLRDQGRAF
CCCCCHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCHH
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFSNLTVY
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSATPGFPRFFENMDKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKMMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DPNGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGMAPKERARRIIEKCAHPDYKPQLT
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHH
EYLNIAEKECLAKKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]