Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 197116743

GI number: 197116743

Start: 418508

End: 420307

Strand: Reverse

Name: recD [H]

Synonym: Gbem_0343

Alternate gene names: 197116743

Gene position: 420307-418508 (Counterclockwise)

Preceding gene: 197116744

Following gene: 197116742

Centisome position: 9.11

GC content: 66.39

Gene sequence:

>1800_bases
ATGGCTGCTGAAACATTCCAATTCAACGACATAGACCGGCAGTTCGCCTCATTCATCTGCCGGCAGGCGGCAAGCCGCGA
CGCGCACCTTGAGGCTGCGGCGGCGCTCTTGAGCCGCGGGGTGACGGCGGGGGACGTCTGCCTCGACCTGGAGAGCGCCC
TGGAAGACGCGCGCGCCGCTGGGTACCGCATCGAATCGGTAGCCGCCTGGCGCCAGAAGCTCGCCGCCCACCCGGTAGTC
GGCGAGCCCGGCGAGTTCAAGCCGCTCATCCTGGACCACGCCGACCGCCTCTACCTGCAGCGCTACTGGCGCTATGAGGA
TGAGCTCGCCGAGGCGATCATGAAACGCGGCAAGACGGTGCGGTTCGACCGGGCGCTGTTGCAGAAGGGGCTCGCACGGC
TTTTTCCTCCCACGCCTGGAGAAACGGACTGGCAGCGGGTTGCTGCCCTCGCCGCCGTCACCAGGCGCTTTTGCGTCATC
TCCGGGGGGCCCGGAACCGGCAAGACCTCGACCGTAGTAAAGGTGCTATCGCTCCTCCTGGAGCAGGCGGAGGAGGCTGG
AACCGGCGCCGGCCTCAGGATCGCACTGGCTGCCCCCACCGGCAAGGCTGCCGCGAGGCTTAAGGAATCGATCAGCGATG
GAGCCCGCTTTGCCGAAGAGGGGGTACGCGGGCTGATCCCGGAGGACGTCTTCACCCTGCACCGCCTGCTCGGTTACCTG
AAGGGTTCCAGCGGCTTCCGCCACAACGCCGATAACCCGCTCCCCTACGACGTGGTAATCGTCGACGAGGCCTCCATGGT
CTCGCTCCCCCTCATGGCCAAGCTGGTCTGCGCCTTGCGGCACGACACCCGCCTGATCCTTTTGGGCGACCGGGACCAGC
TCGCCTCGGTGGAAGCCGGCGCGGTCCTGGGCGACATCTGCGACACCGGCGGCGTGCACGGCTTCTCCCCCGCTTTCGCC
GCCCTGGCAGCCGACCTCGCCGGCGATGCCGTCACCTCCAGCTCCGGCATGTCCCCGCTCGGCGACGCTGTCGTGCAGTT
GCAGAGGAGCTACCGCTTCTCCTCCGCCGGAGGCATCGGCAAAGTTGGTTCGCTGGTCAACGCAGGGGATGCTCCCGGCG
CTTTGTCGGCCTGCCTCGACTCCGCCGTAGCCGGCGTCACGCTGGCGCCGCTCCCCACCGCAGCCGCCCTGGCCGACGCG
CTCGCCAAAAGGATTAGCGAAGGCTACGGCGCCTATCTGCGGGAGGAGAGCCCGGAAGCAGCCTTCGCTGAGTTCAGCCG
GTTCCGTATCCTTTGCGCCATGCGCAGCGGCCCGTTCGGAGTCGAGGCGATCAACCTCCTGGTGCGTCAACGATTGTCCC
AGGCGGGAATGATCCACCCCCGCGGCCGCTGGTACGCCGGCGAGCCGGTCATGATCACCAGGAACGACTACAACCTTGGG
CTCTTCAACGGCGACGTGGGGCTGATTTTGCCCGACGCCGAAACCGGAGGAGAGCTGCGCGCCTTCTTCCCCTCCGGCAC
CGGCGGCATGAGGAAAGTCTTGCCGCTCAGGCTCCCGGAATACGAGTGCGCCTTCGCCATGACCGTGCACAAGAGCCAGG
GTTCCGAGTTCGACCGAGTGCTGCTGGTTCTGCCCGACCGCGACGCGCCGGTCCTGACACGGGAGCTTTTGTACACCGCC
ATAACCCGGGCGAAAACGTCGGTCGACATCCTGGCGAACCAGGAACTTTTTCTCTCCACCGTCACGCGCAGAATTGTCAG
ACGGTCGGGACTGAGAGACAAAACGTGGAAACCCAATTGA

Upstream 100 bases:

>100_bases
AGAGGGCGAGGGGCGACAAGCCTTCCCCGGAATTCCCGGATGAACCTTTGCGAAGGGGGCCGGGTTGGATTTCACGTTTT
AGGATTCACCAGGAAACCAA

Downstream 100 bases:

>100_bases
CAATTGACAATTGACAACGAAAACCGTGGAGAGGCAATTAAGGCTAAAACCCAATTGATAATTGACAATTGATAATTGAC
GATTACAACCTTTCGGATGG

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MAAETFQFNDIDRQFASFICRQAASRDAHLEAAAALLSRGVTAGDVCLDLESALEDARAAGYRIESVAAWRQKLAAHPVV
GEPGEFKPLILDHADRLYLQRYWRYEDELAEAIMKRGKTVRFDRALLQKGLARLFPPTPGETDWQRVAALAAVTRRFCVI
SGGPGTGKTSTVVKVLSLLLEQAEEAGTGAGLRIALAAPTGKAAARLKESISDGARFAEEGVRGLIPEDVFTLHRLLGYL
KGSSGFRHNADNPLPYDVVIVDEASMVSLPLMAKLVCALRHDTRLILLGDRDQLASVEAGAVLGDICDTGGVHGFSPAFA
ALAADLAGDAVTSSSGMSPLGDAVVQLQRSYRFSSAGGIGKVGSLVNAGDAPGALSACLDSAVAGVTLAPLPTAAALADA
LAKRISEGYGAYLREESPEAAFAEFSRFRILCAMRSGPFGVEAINLLVRQRLSQAGMIHPRGRWYAGEPVMITRNDYNLG
LFNGDVGLILPDAETGGELRAFFPSGTGGMRKVLPLRLPEYECAFAMTVHKSQGSEFDRVLLVLPDRDAPVLTRELLYTA
ITRAKTSVDILANQELFLSTVTRRIVRRSGLRDKTWKPN

Sequences:

>Translated_599_residues
MAAETFQFNDIDRQFASFICRQAASRDAHLEAAAALLSRGVTAGDVCLDLESALEDARAAGYRIESVAAWRQKLAAHPVV
GEPGEFKPLILDHADRLYLQRYWRYEDELAEAIMKRGKTVRFDRALLQKGLARLFPPTPGETDWQRVAALAAVTRRFCVI
SGGPGTGKTSTVVKVLSLLLEQAEEAGTGAGLRIALAAPTGKAAARLKESISDGARFAEEGVRGLIPEDVFTLHRLLGYL
KGSSGFRHNADNPLPYDVVIVDEASMVSLPLMAKLVCALRHDTRLILLGDRDQLASVEAGAVLGDICDTGGVHGFSPAFA
ALAADLAGDAVTSSSGMSPLGDAVVQLQRSYRFSSAGGIGKVGSLVNAGDAPGALSACLDSAVAGVTLAPLPTAAALADA
LAKRISEGYGAYLREESPEAAFAEFSRFRILCAMRSGPFGVEAINLLVRQRLSQAGMIHPRGRWYAGEPVMITRNDYNLG
LFNGDVGLILPDAETGGELRAFFPSGTGGMRKVLPLRLPEYECAFAMTVHKSQGSEFDRVLLVLPDRDAPVLTRELLYTA
ITRAKTSVDILANQELFLSTVTRRIVRRSGLRDKTWKPN
>Mature_598_residues
AAETFQFNDIDRQFASFICRQAASRDAHLEAAAALLSRGVTAGDVCLDLESALEDARAAGYRIESVAAWRQKLAAHPVVG
EPGEFKPLILDHADRLYLQRYWRYEDELAEAIMKRGKTVRFDRALLQKGLARLFPPTPGETDWQRVAALAAVTRRFCVIS
GGPGTGKTSTVVKVLSLLLEQAEEAGTGAGLRIALAAPTGKAAARLKESISDGARFAEEGVRGLIPEDVFTLHRLLGYLK
GSSGFRHNADNPLPYDVVIVDEASMVSLPLMAKLVCALRHDTRLILLGDRDQLASVEAGAVLGDICDTGGVHGFSPAFAA
LAADLAGDAVTSSSGMSPLGDAVVQLQRSYRFSSAGGIGKVGSLVNAGDAPGALSACLDSAVAGVTLAPLPTAAALADAL
AKRISEGYGAYLREESPEAAFAEFSRFRILCAMRSGPFGVEAINLLVRQRLSQAGMIHPRGRWYAGEPVMITRNDYNLGL
FNGDVGLILPDAETGGELRAFFPSGTGGMRKVLPLRLPEYECAFAMTVHKSQGSEFDRVLLVLPDRDAPVLTRELLYTAI
TRAKTSVDILANQELFLSTVTRRIVRRSGLRDKTWKPN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=613, Percent_Identity=43.8825448613377, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 64267; Mature: 64136

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAETFQFNDIDRQFASFICRQAASRDAHLEAAAALLSRGVTAGDVCLDLESALEDARAA
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GYRIESVAAWRQKLAAHPVVGEPGEFKPLILDHADRLYLQRYWRYEDELAEAIMKRGKTV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
RFDRALLQKGLARLFPPTPGETDWQRVAALAAVTRRFCVISGGPGTGKTSTVVKVLSLLL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHH
EQAEEAGTGAGLRIALAAPTGKAAARLKESISDGARFAEEGVRGLIPEDVFTLHRLLGYL
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KGSSGFRHNADNPLPYDVVIVDEASMVSLPLMAKLVCALRHDTRLILLGDRDQLASVEAG
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
AVLGDICDTGGVHGFSPAFAALAADLAGDAVTSSSGMSPLGDAVVQLQRSYRFSSAGGIG
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
KVGSLVNAGDAPGALSACLDSAVAGVTLAPLPTAAALADALAKRISEGYGAYLREESPEA
HHHHHHCCCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHCHHHCCCCCHH
AFAEFSRFRILCAMRSGPFGVEAINLLVRQRLSQAGMIHPRGRWYAGEPVMITRNDYNLG
HHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCEEE
LFNGDVGLILPDAETGGELRAFFPSGTGGMRKVLPLRLPEYECAFAMTVHKSQGSEFDRV
EEECCEEEEECCCCCCCCEEEECCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCEE
LLVLPDRDAPVLTRELLYTAITRAKTSVDILANQELFLSTVTRRIVRRSGLRDKTWKPN
EEEECCCCCCHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AAETFQFNDIDRQFASFICRQAASRDAHLEAAAALLSRGVTAGDVCLDLESALEDARAA
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GYRIESVAAWRQKLAAHPVVGEPGEFKPLILDHADRLYLQRYWRYEDELAEAIMKRGKTV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
RFDRALLQKGLARLFPPTPGETDWQRVAALAAVTRRFCVISGGPGTGKTSTVVKVLSLLL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHH
EQAEEAGTGAGLRIALAAPTGKAAARLKESISDGARFAEEGVRGLIPEDVFTLHRLLGYL
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KGSSGFRHNADNPLPYDVVIVDEASMVSLPLMAKLVCALRHDTRLILLGDRDQLASVEAG
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
AVLGDICDTGGVHGFSPAFAALAADLAGDAVTSSSGMSPLGDAVVQLQRSYRFSSAGGIG
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
KVGSLVNAGDAPGALSACLDSAVAGVTLAPLPTAAALADALAKRISEGYGAYLREESPEA
HHHHHHCCCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHCHHHCCCCCHH
AFAEFSRFRILCAMRSGPFGVEAINLLVRQRLSQAGMIHPRGRWYAGEPVMITRNDYNLG
HHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCEEE
LFNGDVGLILPDAETGGELRAFFPSGTGGMRKVLPLRLPEYECAFAMTVHKSQGSEFDRV
EEECCEEEEECCCCCCCCEEEECCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCEE
LLVLPDRDAPVLTRELLYTAITRAKTSVDILANQELFLSTVTRRIVRRSGLRDKTWKPN
EEEECCCCCCHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]