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The map label for this gene is yngJ [H]

Identifier: 197104356

GI number: 197104356

Start: 984602

End: 985750

Strand: Direct

Name: yngJ [H]

Synonym: PHZ_c0890

Alternate gene names: 197104356

Gene position: 984602-985750 (Clockwise)

Preceding gene: 197104353

Following gene: 197104357

Centisome position: 24.64

GC content: 69.97

Gene sequence:

>1149_bases
ATGGCGCTCGACGCCGAAACCCGCGACCAGCTGATCGAGACCGTCCGCCGCTTCGTCGCCGAGCGCCTGCGCCCGCTCGA
GGCGAAGGTGGCCGAGGACGACGCCATTCCCGCCGACGTCATCGAGGAGATGAAAGGGCTGGGCCTCTTCGGCCTGTCGA
TCCCGGCCGAGTACGGCGGCCTCGACCTCAACATGGAGGAGGAGTGCCTGGTCTGCGTCGAGCTCGGCCGCACCAGCCCC
GCCTTCCGCTCGGCCTTCGGCACCAACGTCGGCATCGGCAGCCAGGGCCTGGTGATGTTCGGGACCGAGGCGCAGAAGGC
CAGGTACCTGCCGGGCGTCGCCTCGGGCGAGATCGTCACCTCGTTCGCGCTGACCGAGCCCGAGGCCGGCTCGGATTCCG
GCGCGGTGCAGACCAAGGCCGTGCGCGACGGCGACGACTACGTCCTGAACGGCTCCAAGCGCTACATCACCAACGCCAAC
CGGGCCGACCTCTTCACCGTCATGGCGCGCACCGACCCGTCGAAGCCCGGCGGCTCGGGCGTCTCGGCCTTCCTGGTGGA
GCGCAACCTGCCCGGCGTGACCGTCGGCAAGCCCGAGAAGAAGATGGGCCAGCAGGGCGCGCACATCTGCGACGTCAACT
TCGACAACGTCCGCGTGCCGGCCGAGAACCGCCTGGGCGGCGAGGGCGAGGGCTTCAAGATCGCGATGCAGGTGCTGGAC
CGCGGGCGGCTGCACATCTCGGCGATCTGCGTGGGCGTGGCCGAGCGGCTGATCGCCGACAGCGTCGCCTACGCCGCCGA
GCGCAAGCAGTTCGGCCAGGCGCTGTCGAACTTCCAGCTGGTCCAGGGCATGATCGCCGACTGCAAGACCGAGGCGCTCG
CCGCCAGGGCGCTGGTCATGGAGACCGCCCGCAAGCGCGACGCCGGCCAGAGCGTGACCATGGAGGCCGCGGCGGCCAAG
TACTTCGCCTCCGAGATGGTCGGCCGGGTCGCCGACCGCGCCGTGCAGATCTTCGGCGGCGCCGGCTACATCGCCGAATA
CGGCATCGAGCGCTTCTACCGCGACGTGCGGATCTTCCGCATCTACGAGGGCACCAGCCAGATCCAGCAGGTGATCATCG
CCCGCGAGACGATGAAGCGGGGCGGCTGA

Upstream 100 bases:

>100_bases
GTCCACGTCGAGACCTGGCGCGCGCCGATCCTCGCCGTCGGCCTCGGACGCTTCCGGGAAACCATCGCCACCAAGGCCTG
CCAGTAGGGGGATGAACACC

Downstream 100 bases:

>100_bases
GCATGAGCCAGGCCGTCGAGGACGCAATCTTCGATCTGCTGGACAAGGCCGCGCCCGGCAAGTCTGTCTCTCCCGAGGAC
GTGGCCAAGGCGGTCGACCC

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MALDAETRDQLIETVRRFVAERLRPLEAKVAEDDAIPADVIEEMKGLGLFGLSIPAEYGGLDLNMEEECLVCVELGRTSP
AFRSAFGTNVGIGSQGLVMFGTEAQKARYLPGVASGEIVTSFALTEPEAGSDSGAVQTKAVRDGDDYVLNGSKRYITNAN
RADLFTVMARTDPSKPGGSGVSAFLVERNLPGVTVGKPEKKMGQQGAHICDVNFDNVRVPAENRLGGEGEGFKIAMQVLD
RGRLHISAICVGVAERLIADSVAYAAERKQFGQALSNFQLVQGMIADCKTEALAARALVMETARKRDAGQSVTMEAAAAK
YFASEMVGRVADRAVQIFGGAGYIAEYGIERFYRDVRIFRIYEGTSQIQQVIIARETMKRGG

Sequences:

>Translated_382_residues
MALDAETRDQLIETVRRFVAERLRPLEAKVAEDDAIPADVIEEMKGLGLFGLSIPAEYGGLDLNMEEECLVCVELGRTSP
AFRSAFGTNVGIGSQGLVMFGTEAQKARYLPGVASGEIVTSFALTEPEAGSDSGAVQTKAVRDGDDYVLNGSKRYITNAN
RADLFTVMARTDPSKPGGSGVSAFLVERNLPGVTVGKPEKKMGQQGAHICDVNFDNVRVPAENRLGGEGEGFKIAMQVLD
RGRLHISAICVGVAERLIADSVAYAAERKQFGQALSNFQLVQGMIADCKTEALAARALVMETARKRDAGQSVTMEAAAAK
YFASEMVGRVADRAVQIFGGAGYIAEYGIERFYRDVRIFRIYEGTSQIQQVIIARETMKRGG
>Mature_381_residues
ALDAETRDQLIETVRRFVAERLRPLEAKVAEDDAIPADVIEEMKGLGLFGLSIPAEYGGLDLNMEEECLVCVELGRTSPA
FRSAFGTNVGIGSQGLVMFGTEAQKARYLPGVASGEIVTSFALTEPEAGSDSGAVQTKAVRDGDDYVLNGSKRYITNANR
ADLFTVMARTDPSKPGGSGVSAFLVERNLPGVTVGKPEKKMGQQGAHICDVNFDNVRVPAENRLGGEGEGFKIAMQVLDR
GRLHISAICVGVAERLIADSVAYAAERKQFGQALSNFQLVQGMIADCKTEALAARALVMETARKRDAGQSVTMEAAAAKY
FASEMVGRVADRAVQIFGGAGYIAEYGIERFYRDVRIFRIYEGTSQIQQVIIARETMKRGG

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=386, Percent_Identity=38.860103626943, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI4557235, Length=377, Percent_Identity=40.3183023872679, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI76496475, Length=377, Percent_Identity=40.3183023872679, Blast_Score=268, Evalue=6e-72,
Organism=Homo sapiens, GI4501859, Length=363, Percent_Identity=39.1184573002755, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI4557233, Length=374, Percent_Identity=38.2352941176471, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=35.8090185676393, Blast_Score=254, Evalue=7e-68,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=35.8090185676393, Blast_Score=254, Evalue=7e-68,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=34.2245989304813, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226958414, Length=366, Percent_Identity=34.9726775956284, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI7656849, Length=367, Percent_Identity=32.425068119891, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4501857, Length=372, Percent_Identity=32.258064516129, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=31.5656565656566, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=31.5656565656566, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4503943, Length=373, Percent_Identity=28.9544235924933, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI38505218, Length=409, Percent_Identity=29.3398533007335, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=28.5318559556787, Blast_Score=146, Evalue=4e-35,
Organism=Escherichia coli, GI1786223, Length=376, Percent_Identity=29.5212765957447, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=28.3819628647215, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI87081702, Length=337, Percent_Identity=26.4094955489614, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI87082384, Length=289, Percent_Identity=24.9134948096886, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=374, Percent_Identity=38.2352941176471, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17570075, Length=369, Percent_Identity=38.4823848238482, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=39.3530997304582, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=38.5026737967914, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=40.6876790830946, Blast_Score=258, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17506239, Length=363, Percent_Identity=38.5674931129477, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17538396, Length=371, Percent_Identity=33.9622641509434, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71985192, Length=309, Percent_Identity=38.8349514563107, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=30.0531914893617, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=39.7111913357401, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=30.7692307692308, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=370, Percent_Identity=31.0810810810811, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=38.5281385281385, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=35.8974358974359, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=30.0531914893617, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=36.6666666666667, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=31.2328767123288, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17531913, Length=174, Percent_Identity=32.7586206896552, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=273, Percent_Identity=27.1062271062271, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=273, Percent_Identity=27.1062271062271, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363737, Length=387, Percent_Identity=38.7596899224806, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24660351, Length=372, Percent_Identity=39.247311827957, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=40.2203856749311, Blast_Score=264, Evalue=7e-71,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=38.1333333333333, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=36.0313315926893, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=34.4919786096257, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19920834, Length=367, Percent_Identity=29.4277929155313, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24652780, Length=347, Percent_Identity=24.7838616714697, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41168; Mature: 41037

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDAETRDQLIETVRRFVAERLRPLEAKVAEDDAIPADVIEEMKGLGLFGLSIPAEYGG
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCEEEEEECCCCCCC
LDLNMEEECLVCVELGRTSPAFRSAFGTNVGIGSQGLVMFGTEAQKARYLPGVASGEIVT
CCCCCCHHHEEEEECCCCCHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCEEE
SFALTEPEAGSDSGAVQTKAVRDGDDYVLNGSKRYITNANRADLFTVMARTDPSKPGGSG
EEEECCCCCCCCCCCEEEEEEECCCCEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCC
VSAFLVERNLPGVTVGKPEKKMGQQGAHICDVNFDNVRVPAENRLGGEGEGFKIAMQVLD
CEEEEEECCCCCCCCCCCHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCHHHHHHHHH
RGRLHISAICVGVAERLIADSVAYAAERKQFGQALSNFQLVQGMIADCKTEALAARALVM
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETARKRDAGQSVTMEAAAAKYFASEMVGRVADRAVQIFGGAGYIAEYGIERFYRDVRIFR
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEE
IYEGTSQIQQVIIARETMKRGG
EECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALDAETRDQLIETVRRFVAERLRPLEAKVAEDDAIPADVIEEMKGLGLFGLSIPAEYGG
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCEEEEEECCCCCCC
LDLNMEEECLVCVELGRTSPAFRSAFGTNVGIGSQGLVMFGTEAQKARYLPGVASGEIVT
CCCCCCHHHEEEEECCCCCHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCEEE
SFALTEPEAGSDSGAVQTKAVRDGDDYVLNGSKRYITNANRADLFTVMARTDPSKPGGSG
EEEECCCCCCCCCCCEEEEEEECCCCEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCC
VSAFLVERNLPGVTVGKPEKKMGQQGAHICDVNFDNVRVPAENRLGGEGEGFKIAMQVLD
CEEEEEECCCCCCCCCCCHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCHHHHHHHHH
RGRLHISAICVGVAERLIADSVAYAAERKQFGQALSNFQLVQGMIADCKTEALAARALVM
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETARKRDAGQSVTMEAAAAKYFASEMVGRVADRAVQIFGGAGYIAEYGIERFYRDVRIFR
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEE
IYEGTSQIQQVIIARETMKRGG
EECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]