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The map label for this gene is iolS [H]

Identifier: 197104351

GI number: 197104351

Start: 979092

End: 980090

Strand: Direct

Name: iolS [H]

Synonym: PHZ_c0885

Alternate gene names: 197104351

Gene position: 979092-980090 (Clockwise)

Preceding gene: 197104345

Following gene: 197104352

Centisome position: 24.5

GC content: 71.87

Gene sequence:

>999_bases
ATGCACAGACGCAAACTCGGAACCCAGGGCCTGGAGGTCTCGGCGATCGGCTTCGGCTGCATGGGGCTGTCCGGCGTCTA
CAACGCCCCAGTCGAGGCGGCGCAGGCCGAGGCGCTGGTCGCGCGCGCCGTCGAGCTGGGCGTCACCTTCTTCGATACGG
CCGAGATCTACGGCATGACCGCCAACGAGGTGCTGGTGGGGGCGGCGCTGAAGCCCTTCCGGGGCCGGGTGCAGATCGCC
ACCAAGTTCGGCTTCGACCTGGAGGCCGCCCGCGCGGCCGGGCGCCCGGCGGGCACGAACAGCCGCCCCGACAACATCCG
CGCGGTCGCCGACGCCTCGCTGAAGCGCCTGGGCGTGGACGTCATCGACCTCTTCTACCAGCACCGGGTGGACCCGAACG
TGCCGATCGAGGACGTGGCGGGCGCGGTGGGCGAGCTGGTGAAGGCCGGCAAGGTGCGCTGCTTCGGGCTGTCCGAGGCC
GGACCCGAGACGATCCGCCGGGCGCACGTCGTGCATCCGGTCACGGCCCTGCAGTCGGAGTACTCGCTGTGGACGCGGGA
CCCCGAGACGTCGGTCCTGCCGGTCTGTCGCGAACTCGGGATCGGCTTCGTGCCCTACAGCCCGCTGGGCCGGGGCTTCC
TGGCCGGGGCGGTGAAGGGCCAGGACTCGCTGGTGGAGAACGACTTCCGCCGGTTCATGCCCAGGTTCCAGGGTCAGGCG
CTGCAGAAGAACCTGCCGCTGGTGGAGACCCTGACGCGGCTGGCGGCCGAGAAGGGCCATACGCCGGCCCAGCTCGCGCT
GGCCTGGCTGCTGGCGCAGGGCCCCGACATCGTGCCCATCCCCGGCACGACGAAGGTCCATCGCCTGGAGGAGAACGCCG
GCGCCGCCGACGTGACGCTCGGCCCGGACGATCTGGCGGCGATCGCGGCGGCCGTGCCCGAGACCGCGGTGGAAGGCGCC
CGCTACGACGAACGCGGCCTCTCGATGGTGGGTCTCTGA

Upstream 100 bases:

>100_bases
TCGCGATTAAACCTTCGTAATGCTCAACCGGGCCGCGCCGAGCTTGCGGCCGGCCGCCGCGAGGCGCTTAAGATTCCCGC
TCCGGAAGAAGGAGCCGCCC

Downstream 100 bases:

>100_bases
GGGTAGGACCTTAGGGCGCGCTTGCGCTTCCTAGGGTTCTGGCGCCTGTATCCGCCCACGCGGGCGGACTCGGCGTGCAT
GCGCATCGGGGCCCGCGCAT

Product: oxidoreductase, aldo/keto reductase family

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MHRRKLGTQGLEVSAIGFGCMGLSGVYNAPVEAAQAEALVARAVELGVTFFDTAEIYGMTANEVLVGAALKPFRGRVQIA
TKFGFDLEAARAAGRPAGTNSRPDNIRAVADASLKRLGVDVIDLFYQHRVDPNVPIEDVAGAVGELVKAGKVRCFGLSEA
GPETIRRAHVVHPVTALQSEYSLWTRDPETSVLPVCRELGIGFVPYSPLGRGFLAGAVKGQDSLVENDFRRFMPRFQGQA
LQKNLPLVETLTRLAAEKGHTPAQLALAWLLAQGPDIVPIPGTTKVHRLEENAGAADVTLGPDDLAAIAAAVPETAVEGA
RYDERGLSMVGL

Sequences:

>Translated_332_residues
MHRRKLGTQGLEVSAIGFGCMGLSGVYNAPVEAAQAEALVARAVELGVTFFDTAEIYGMTANEVLVGAALKPFRGRVQIA
TKFGFDLEAARAAGRPAGTNSRPDNIRAVADASLKRLGVDVIDLFYQHRVDPNVPIEDVAGAVGELVKAGKVRCFGLSEA
GPETIRRAHVVHPVTALQSEYSLWTRDPETSVLPVCRELGIGFVPYSPLGRGFLAGAVKGQDSLVENDFRRFMPRFQGQA
LQKNLPLVETLTRLAAEKGHTPAQLALAWLLAQGPDIVPIPGTTKVHRLEENAGAADVTLGPDDLAAIAAAVPETAVEGA
RYDERGLSMVGL
>Mature_332_residues
MHRRKLGTQGLEVSAIGFGCMGLSGVYNAPVEAAQAEALVARAVELGVTFFDTAEIYGMTANEVLVGAALKPFRGRVQIA
TKFGFDLEAARAAGRPAGTNSRPDNIRAVADASLKRLGVDVIDLFYQHRVDPNVPIEDVAGAVGELVKAGKVRCFGLSEA
GPETIRRAHVVHPVTALQSEYSLWTRDPETSVLPVCRELGIGFVPYSPLGRGFLAGAVKGQDSLVENDFRRFMPRFQGQA
LQKNLPLVETLTRLAAEKGHTPAQLALAWLLAQGPDIVPIPGTTKVHRLEENAGAADVTLGPDDLAAIAAAVPETAVEGA
RYDERGLSMVGL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=28.343949044586, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436966, Length=316, Percent_Identity=28.1645569620253, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436962, Length=316, Percent_Identity=28.1645569620253, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=27.3006134969325, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=27.2445820433437, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI27436971, Length=334, Percent_Identity=28.1437125748503, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI223718702, Length=306, Percent_Identity=29.0849673202614, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI41152114, Length=322, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI41327764, Length=293, Percent_Identity=29.3515358361775, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=33.5384615384615, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=30.3303303303303, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=30.7936507936508, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=29.8076923076923, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=28.7709497206704, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788081, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994888, Length=305, Percent_Identity=28.1967213114754, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325384, Length=339, Percent_Identity=30.3834808259587, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=25.3012048192771, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=25.6172839506173, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=290, Percent_Identity=24.4827586206897, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=25.8687258687259, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=327, Percent_Identity=24.4648318042813, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646155, Length=227, Percent_Identity=28.6343612334802, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35298; Mature: 35298

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRRKLGTQGLEVSAIGFGCMGLSGVYNAPVEAAQAEALVARAVELGVTFFDTAEIYGMT
CCCCCCCCCCCEEEEEEECHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHCCCC
ANEVLVGAALKPFRGRVQIATKFGFDLEAARAAGRPAGTNSRPDNIRAVADASLKRLGVD
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VIDLFYQHRVDPNVPIEDVAGAVGELVKAGKVRCFGLSEAGPETIRRAHVVHPVTALQSE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YSLWTRDPETSVLPVCRELGIGFVPYSPLGRGFLAGAVKGQDSLVENDFRRFMPRFQGQA
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCHH
LQKNLPLVETLTRLAAEKGHTPAQLALAWLLAQGPDIVPIPGTTKVHRLEENAGAADVTL
HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCHHHEECCCCCCCEEEE
GPDDLAAIAAAVPETAVEGARYDERGLSMVGL
CHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHRRKLGTQGLEVSAIGFGCMGLSGVYNAPVEAAQAEALVARAVELGVTFFDTAEIYGMT
CCCCCCCCCCCEEEEEEECHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHCCCC
ANEVLVGAALKPFRGRVQIATKFGFDLEAARAAGRPAGTNSRPDNIRAVADASLKRLGVD
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VIDLFYQHRVDPNVPIEDVAGAVGELVKAGKVRCFGLSEAGPETIRRAHVVHPVTALQSE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YSLWTRDPETSVLPVCRELGIGFVPYSPLGRGFLAGAVKGQDSLVENDFRRFMPRFQGQA
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCHH
LQKNLPLVETLTRLAAEKGHTPAQLALAWLLAQGPDIVPIPGTTKVHRLEENAGAADVTL
HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCHHHEECCCCCCCEEEE
GPDDLAAIAAAVPETAVEGARYDERGLSMVGL
CHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]