Click here to switch to the map view.

The map label for this gene is acdA [H]

Identifier: 197104276

GI number: 197104276

Start: 894053

End: 895276

Strand: Direct

Name: acdA [H]

Synonym: PHZ_c0810

Alternate gene names: 197104276

Gene position: 894053-895276 (Clockwise)

Preceding gene: 197104275

Following gene: 197104280

Centisome position: 22.37

GC content: 66.83

Gene sequence:

>1224_bases
ATGGACCTGGATTTCTCCCCCGAAGAGCTCGCCTTCCGCGACGAGGTCCGCGCGTTCATCGCCGAGGCCTACGACGACGA
CATGCGGGCCCGCATGGCCCAGTCGAAGAACGGTTACCTCGACAAGGAGAGCCAGGTCCGCTGGCTGAAGAAGCTGCACG
AGAAGGGCTGGATCGCGCCCGACTGGCCGGTCGAGTACGGCGGCACGGGCTGGAGCCTCGGCAAGAAGTACGTCTTCGAC
ATGGAGATGGCGCTGGCCGGCGCCCCCTCCACCTCGAACATGGGCCTCAAGATGTGCGCCCCCGTGGTGATGGCCTTCGG
GACCGACGAGCAGAAGCAGCAGCACCTGCCGAAGATCCTCTCCACCGACGTCTGGTGGTGCCAGGGCTACTCCGAGCCGG
GCTCGGGCTCGGACCTCGCGTCGCTGGCCCTCAAGGCCGAGCGGGACGGCGACCACTATGTCCTGAACGGCTCTAAGACC
TGGACGACCCTGGCCCAGTGGGCCGACTGGATGTTCTGCCTCGTGCGGACCTCGAACGAGGACATCCGCCAGAAGGGCAT
CTCGTTCCTGCTGATCGACATGAAGACGCCGGGCATCTCGATCCGGCCGATCCCGACGCTGGACGGCCCGGTCGAGGGCG
AGCAGGAGATCAACGAGACGTTCTTCGACAACGTCCGCGTGCCGGTCGCCAACCGCATCGGCAAGGAAGGCGAGGGCTGG
ACCTACGCCAAGTACCTGTTGCAGTTCGAGCGCGGCAACGCCTACGCGCCCGGCCTGCAGAACCAGCTGCGCAAGGTGCG
CAAGATCGCCAGCCTCGAGCGCTCCGACCGCGGCGGTTCGATGATGGGCGACCCCGACTTCCGGCGGAAGCTGTCGGAGG
TGGAGATCAAGGTCGAGGCCCTGAACGCCACCGAACTGCGGATCTTCGCCGGCCGCGCCAACGGCGAGGCCATGGGGGCG
GTGTCGTCCATGCTGAAGCTGGAAGGCAGCCAGATGCAGCAGGCGATCACCGAGCTGGCCCTGGAGGCCGCCGGCCTCTA
CGCCCAGCCGTTCGTGCGCGACACCTGGGCCGAGCTGAACGGCGAGACCAACGCCTTCCGCGCGGGCCCCGACTACGCGG
CCACCGTCGCGCCGCAGTACTTCAACTACCGCAAGACCTCGATCTACGCCGGCTCGAACGAGATCCAGCACAACATCATG
GCCAAGATGGTGCTCGGCCTCTGA

Upstream 100 bases:

>100_bases
ACGGCGGCACCGAGTACTTCAAGGCCGCCGGGCCGAAGTTCGCCGGCTTCCTCGCCGGCCGGCCCGAGATCGAATACCTG
GACGGCGTGGGCTGACCGCC

Downstream 100 bases:

>100_bases
GCCGTCTCAGGCGGCGGGCCGCCGCCCAGGCGTGGCCGCCTGCAGCTGGGTGGAGGCGCCGTGCGGCACCCGCGCGCTCG
CCAGCACCTGGCCCGGGCGG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MDLDFSPEELAFRDEVRAFIAEAYDDDMRARMAQSKNGYLDKESQVRWLKKLHEKGWIAPDWPVEYGGTGWSLGKKYVFD
MEMALAGAPSTSNMGLKMCAPVVMAFGTDEQKQQHLPKILSTDVWWCQGYSEPGSGSDLASLALKAERDGDHYVLNGSKT
WTTLAQWADWMFCLVRTSNEDIRQKGISFLLIDMKTPGISIRPIPTLDGPVEGEQEINETFFDNVRVPVANRIGKEGEGW
TYAKYLLQFERGNAYAPGLQNQLRKVRKIASLERSDRGGSMMGDPDFRRKLSEVEIKVEALNATELRIFAGRANGEAMGA
VSSMLKLEGSQMQQAITELALEAAGLYAQPFVRDTWAELNGETNAFRAGPDYAATVAPQYFNYRKTSIYAGSNEIQHNIM
AKMVLGL

Sequences:

>Translated_407_residues
MDLDFSPEELAFRDEVRAFIAEAYDDDMRARMAQSKNGYLDKESQVRWLKKLHEKGWIAPDWPVEYGGTGWSLGKKYVFD
MEMALAGAPSTSNMGLKMCAPVVMAFGTDEQKQQHLPKILSTDVWWCQGYSEPGSGSDLASLALKAERDGDHYVLNGSKT
WTTLAQWADWMFCLVRTSNEDIRQKGISFLLIDMKTPGISIRPIPTLDGPVEGEQEINETFFDNVRVPVANRIGKEGEGW
TYAKYLLQFERGNAYAPGLQNQLRKVRKIASLERSDRGGSMMGDPDFRRKLSEVEIKVEALNATELRIFAGRANGEAMGA
VSSMLKLEGSQMQQAITELALEAAGLYAQPFVRDTWAELNGETNAFRAGPDYAATVAPQYFNYRKTSIYAGSNEIQHNIM
AKMVLGL
>Mature_407_residues
MDLDFSPEELAFRDEVRAFIAEAYDDDMRARMAQSKNGYLDKESQVRWLKKLHEKGWIAPDWPVEYGGTGWSLGKKYVFD
MEMALAGAPSTSNMGLKMCAPVVMAFGTDEQKQQHLPKILSTDVWWCQGYSEPGSGSDLASLALKAERDGDHYVLNGSKT
WTTLAQWADWMFCLVRTSNEDIRQKGISFLLIDMKTPGISIRPIPTLDGPVEGEQEINETFFDNVRVPVANRIGKEGEGW
TYAKYLLQFERGNAYAPGLQNQLRKVRKIASLERSDRGGSMMGDPDFRRKLSEVEIKVEALNATELRIFAGRANGEAMGA
VSSMLKLEGSQMQQAITELALEAAGLYAQPFVRDTWAELNGETNAFRAGPDYAATVAPQYFNYRKTSIYAGSNEIQHNIM
AKMVLGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=199, Percent_Identity=32.6633165829146, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4501859, Length=243, Percent_Identity=31.2757201646091, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226958414, Length=218, Percent_Identity=29.8165137614679, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=26.6318537859008, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI226958412, Length=219, Percent_Identity=28.7671232876712, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI21361497, Length=246, Percent_Identity=30.4878048780488, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4501857, Length=410, Percent_Identity=22.6829268292683, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557231, Length=316, Percent_Identity=26.8987341772152, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187960098, Length=316, Percent_Identity=26.8987341772152, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557235, Length=231, Percent_Identity=29.8701298701299, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI76496475, Length=231, Percent_Identity=29.8701298701299, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38505218, Length=185, Percent_Identity=33.5135135135135, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI48976061, Length=350, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI211971008, Length=350, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=254, Percent_Identity=25.5905511811024, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786223, Length=251, Percent_Identity=24.7011952191235, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=315, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17551932, Length=366, Percent_Identity=28.6885245901639, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17505929, Length=360, Percent_Identity=27.2222222222222, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=27.7486910994764, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=253, Percent_Identity=30.4347826086957, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=244, Percent_Identity=28.6885245901639, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=301, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=284, Percent_Identity=27.112676056338, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=192, Percent_Identity=30.7291666666667, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=202, Percent_Identity=28.7128712871287, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=156, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=253, Percent_Identity=29.2490118577075, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=225, Percent_Identity=27.1111111111111, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24666513, Length=260, Percent_Identity=29.6153846153846, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21355753, Length=205, Percent_Identity=32.6829268292683, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356377, Length=390, Percent_Identity=26.4102564102564, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281363737, Length=230, Percent_Identity=28.695652173913, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646207, Length=361, Percent_Identity=25.4847645429363, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24660351, Length=222, Percent_Identity=28.3783783783784, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 45536; Mature: 45536

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDFSPEELAFRDEVRAFIAEAYDDDMRARMAQSKNGYLDKESQVRWLKKLHEKGWIAP
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
DWPVEYGGTGWSLGKKYVFDMEMALAGAPSTSNMGLKMCAPVVMAFGTDEQKQQHLPKIL
CCCCCCCCCCHHCCCEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
STDVWWCQGYSEPGSGSDLASLALKAERDGDHYVLNGSKTWTTLAQWADWMFCLVRTSNE
CCCCCEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHEEEEECCCH
DIRQKGISFLLIDMKTPGISIRPIPTLDGPVEGEQEINETFFDNVRVPVANRIGKEGEGW
HHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCH
TYAKYLLQFERGNAYAPGLQNQLRKVRKIASLERSDRGGSMMGDPDFRRKLSEVEIKVEA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEEEEEE
LNATELRIFAGRANGEAMGAVSSMLKLEGSQMQQAITELALEAAGLYAQPFVRDTWAELN
ECCEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHCC
GETNAFRAGPDYAATVAPQYFNYRKTSIYAGSNEIQHNIMAKMVLGL
CCCCCEECCCCCHHHCCHHHHCCEEEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLDFSPEELAFRDEVRAFIAEAYDDDMRARMAQSKNGYLDKESQVRWLKKLHEKGWIAP
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
DWPVEYGGTGWSLGKKYVFDMEMALAGAPSTSNMGLKMCAPVVMAFGTDEQKQQHLPKIL
CCCCCCCCCCHHCCCEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
STDVWWCQGYSEPGSGSDLASLALKAERDGDHYVLNGSKTWTTLAQWADWMFCLVRTSNE
CCCCCEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHEEEEECCCH
DIRQKGISFLLIDMKTPGISIRPIPTLDGPVEGEQEINETFFDNVRVPVANRIGKEGEGW
HHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCH
TYAKYLLQFERGNAYAPGLQNQLRKVRKIASLERSDRGGSMMGDPDFRRKLSEVEIKVEA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEEEEEE
LNATELRIFAGRANGEAMGAVSSMLKLEGSQMQQAITELALEAAGLYAQPFVRDTWAELN
ECCEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHCC
GETNAFRAGPDYAATVAPQYFNYRKTSIYAGSNEIQHNIMAKMVLGL
CCCCCEECCCCCHHHCCHHHHCCEEEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]