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The map label for this gene is grxC [H]

Identifier: 197104235

GI number: 197104235

Start: 847410

End: 847667

Strand: Direct

Name: grxC [H]

Synonym: PHZ_c0769

Alternate gene names: 197104235

Gene position: 847410-847667 (Clockwise)

Preceding gene: 197104234

Following gene: 197104236

Centisome position: 21.21

GC content: 63.57

Gene sequence:

>258_bases
ATGGCCAAAGTCACGATCTACACCAAGCCCTACTGCCCCTATTGCATCCGGGCGATCAGCCTGCTGGAGCAGAAGGGCGT
CGATTTCACCGAGATCGAAGCCGCCTTCGATCCCGAGAAGAAGGCGGAGATGGTCCAGCGGTCCGGCCGCATGACCTTCC
CGCAGATCTTCATCGGCGAGCGGCACATCGGCGGCTGCGACGACATGATCGCGCTGGAGCGAGAGGGCAAGCTCGACCCC
CTGCTGCAGGCGGCGTGA

Upstream 100 bases:

>100_bases
CGGGGGCGACATCCGTCAATGTCGCCGTCGTGGCGCGCGTTAAGGAAGCGACGGGACTCACCCTATGAAGCTGAAGCGAC
AGCTCCTTCGTTAAGGCGCC

Downstream 100 bases:

>100_bases
GCCTTCCCTCCCGGCCCGGGCGGCTGGCGCGGCCTTTCCCTCCCCATTAAGGGAGGGGGATGAAGGTCGGCCTGATCCAG
ACCCGCACGCCCGCCACCCA

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAKVTIYTKPYCPYCIRAISLLEQKGVDFTEIEAAFDPEKKAEMVQRSGRMTFPQIFIGERHIGGCDDMIALEREGKLDP
LLQAA

Sequences:

>Translated_85_residues
MAKVTIYTKPYCPYCIRAISLLEQKGVDFTEIEAAFDPEKKAEMVQRSGRMTFPQIFIGERHIGGCDDMIALEREGKLDP
LLQAA
>Mature_84_residues
AKVTIYTKPYCPYCIRAISLLEQKGVDFTEIEAAFDPEKKAEMVQRSGRMTFPQIFIGERHIGGCDDMIALEREGKLDPL
LQAA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=57.8313253012048, Blast_Score=102, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25147337, Length=87, Percent_Identity=36.7816091954023, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9595; Mature: 9464

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVTIYTKPYCPYCIRAISLLEQKGVDFTEIEAAFDPEKKAEMVQRSGRMTFPQIFIGE
CCEEEEEECCCCHHHHHHHHHHHHCCCCCEEHHCCCCCHHHHHHHHHCCCCCCCEEEECC
RHIGGCDDMIALEREGKLDPLLQAA
CCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AKVTIYTKPYCPYCIRAISLLEQKGVDFTEIEAAFDPEKKAEMVQRSGRMTFPQIFIGE
CEEEEEECCCCHHHHHHHHHHHHCCCCCEEHHCCCCCHHHHHHHHHCCCCCCCEEEECC
RHIGGCDDMIALEREGKLDPLLQAA
CCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]