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The map label for this gene is trxB [H]

Identifier: 195952997

GI number: 195952997

Start: 555483

End: 556421

Strand: Direct

Name: trxB [H]

Synonym: HY04AAS1_0622

Alternate gene names: 195952997

Gene position: 555483-556421 (Clockwise)

Preceding gene: 195952996

Following gene: 195952998

Centisome position: 35.62

GC content: 39.19

Gene sequence:

>939_bases
ATGATAAACACTCATAAAATTTACGATTGTATAATAGTTGGTGGAGGTCCGGCCGGTCTTACAGCCGGGCTTTATTGTGC
TAGAGCCAAGATGGATGTAATACTTTTGGAAAAATCAACACTTGGTGGCCAAATAGCTATAACGGATTTAGTAGAAAACT
ATCCTGGGTTTCCAGAAGGTATAAGCGGCAAAGAACTTACAAGCAAATTCAAAGCTCAAGCTGAAAGGTTTGGGCTTAAA
ATCCATAGGCAAGGTGTGATATCTGTGGAAAACGACAACGATAATATTAAAATCCTTAAACTTGACAATGGATCAGAGTT
AAGAGCGAAAACCGTCATAATTACCACTGGTGCCCGTATGAGGACCCTTGACGTACCAGGCGAGAAAGAATTTTTAAATA
GAGGTGTATCTTATTGCGCTACTTGTGATGGTGCTCTTTTTGAGGATGTGCCAATAGCTGTTGTCGGCGGTGGTGATTCT
GCAACGCAAGAAGCGATCTTTTTAACACGCTTTGCCTCAAAAGTTTACCTAATACACAGAAGAGATAAACTAAGGGCAAA
ACCACTTCTTCAAGACAGAGTTTTCTCTAATCCAAAAATAGAGTTTGTACCAAACAAAGTGGTAAAAGCCATCCAAGGTA
GCGATTTTGTTAATTCTTTATTGTTGGAAGATACTAAAACCGGTGAACATTCTATCTTATCCGTAGATGGTGTCTTTATA
TTTATAGGTATGATACCGGCCACAGATATAGTAAAAGATTTGGTAGAGTTAGATGAGTATGGATATATAAAGGTTAACGA
TAATATGGAAACTTCAGTATCAGGCATATTCGCTGCTGGGGATTGTAGAAGTGGTCAAACAGGTCAAGTTGTTGTTGCTG
CTGGAGAGGGTTGCATAGCTGCCATGGCTGCTGAAAGATATCTACAAAATTCCGAATAA

Upstream 100 bases:

>100_bases
CTATACCTACTATAATGATGTTTAAAAATGGCGAAGTGGTAGATACAAGAGTTGGTGTACAACCAGAAGATGGCTTAAGA
AAGATGATCAAAAACAATTT

Downstream 100 bases:

>100_bases
GATCTAATGAATACTTTACAGCAAGCGGTAAATATATGGTATAGCAGTTCCAATACCACAAATATAATAATAGTTTTATG
GATGCTGTTAACCGTTATAT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MINTHKIYDCIIVGGGPAGLTAGLYCARAKMDVILLEKSTLGGQIAITDLVENYPGFPEGISGKELTSKFKAQAERFGLK
IHRQGVISVENDNDNIKILKLDNGSELRAKTVIITTGARMRTLDVPGEKEFLNRGVSYCATCDGALFEDVPIAVVGGGDS
ATQEAIFLTRFASKVYLIHRRDKLRAKPLLQDRVFSNPKIEFVPNKVVKAIQGSDFVNSLLLEDTKTGEHSILSVDGVFI
FIGMIPATDIVKDLVELDEYGYIKVNDNMETSVSGIFAAGDCRSGQTGQVVVAAGEGCIAAMAAERYLQNSE

Sequences:

>Translated_312_residues
MINTHKIYDCIIVGGGPAGLTAGLYCARAKMDVILLEKSTLGGQIAITDLVENYPGFPEGISGKELTSKFKAQAERFGLK
IHRQGVISVENDNDNIKILKLDNGSELRAKTVIITTGARMRTLDVPGEKEFLNRGVSYCATCDGALFEDVPIAVVGGGDS
ATQEAIFLTRFASKVYLIHRRDKLRAKPLLQDRVFSNPKIEFVPNKVVKAIQGSDFVNSLLLEDTKTGEHSILSVDGVFI
FIGMIPATDIVKDLVELDEYGYIKVNDNMETSVSGIFAAGDCRSGQTGQVVVAAGEGCIAAMAAERYLQNSE
>Mature_312_residues
MINTHKIYDCIIVGGGPAGLTAGLYCARAKMDVILLEKSTLGGQIAITDLVENYPGFPEGISGKELTSKFKAQAERFGLK
IHRQGVISVENDNDNIKILKLDNGSELRAKTVIITTGARMRTLDVPGEKEFLNRGVSYCATCDGALFEDVPIAVVGGGDS
ATQEAIFLTRFASKVYLIHRRDKLRAKPLLQDRVFSNPKIEFVPNKVVKAIQGSDFVNSLLLEDTKTGEHSILSVDGVFI
FIGMIPATDIVKDLVELDEYGYIKVNDNMETSVSGIFAAGDCRSGQTGQVVVAAGEGCIAAMAAERYLQNSE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=39.1167192429022, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=32.484076433121, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6321898, Length=319, Percent_Identity=41.3793103448276, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=40.7051282051282, Blast_Score=236, Evalue=5e-63,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33727; Mature: 33727

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTHKIYDCIIVGGGPAGLTAGLYCARAKMDVILLEKSTLGGQIAITDLVENYPGFPEG
CCCCEEEEEEEEECCCCHHHHHHHEEECCCEEEEEEEECCCCCEEEEEEHHHHCCCCCCC
ISGKELTSKFKAQAERFGLKIHRQGVISVENDNDNIKILKLDNGSELRAKTVIITTGARM
CCCHHHHHHHHHHHHHCCEEEEECEEEEEECCCCCEEEEEECCCCCEEEEEEEEECCCEE
RTLDVPGEKEFLNRGVSYCATCDGALFEDVPIAVVGGGDSATQEAIFLTRFASKVYLIHR
EEEECCCHHHHHHCCCHHEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCEEEEEEE
RDKLRAKPLLQDRVFSNPKIEFVPNKVVKAIQGSDFVNSLLLEDTKTGEHSILSVDGVFI
CCCCCCCCCHHHHHCCCCCEEECCHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEECCEEE
FIGMIPATDIVKDLVELDEYGYIKVNDNMETSVSGIFAAGDCRSGQTGQVVVAAGEGCIA
EEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCHHH
AMAAERYLQNSE
HHHHHHHHCCCC
>Mature Secondary Structure
MINTHKIYDCIIVGGGPAGLTAGLYCARAKMDVILLEKSTLGGQIAITDLVENYPGFPEG
CCCCEEEEEEEEECCCCHHHHHHHEEECCCEEEEEEEECCCCCEEEEEEHHHHCCCCCCC
ISGKELTSKFKAQAERFGLKIHRQGVISVENDNDNIKILKLDNGSELRAKTVIITTGARM
CCCHHHHHHHHHHHHHCCEEEEECEEEEEECCCCCEEEEEECCCCCEEEEEEEEECCCEE
RTLDVPGEKEFLNRGVSYCATCDGALFEDVPIAVVGGGDSATQEAIFLTRFASKVYLIHR
EEEECCCHHHHHHCCCHHEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCEEEEEEE
RDKLRAKPLLQDRVFSNPKIEFVPNKVVKAIQGSDFVNSLLLEDTKTGEHSILSVDGVFI
CCCCCCCCCHHHHHCCCCCEEECCHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEECCEEE
FIGMIPATDIVKDLVELDEYGYIKVNDNMETSVSGIFAAGDCRSGQTGQVVVAAGEGCIA
EEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCHHH
AMAAERYLQNSE
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]