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The map label for this gene is mlaB [H]

Identifier: 194738002

GI number: 194738002

Start: 3375782

End: 3376078

Strand: Reverse

Name: mlaB [H]

Synonym: SeSA_A3501

Alternate gene names: 194738002

Gene position: 3376078-3375782 (Counterclockwise)

Preceding gene: 194736628

Following gene: 194737647

Centisome position: 71.69

GC content: 59.26

Gene sequence:

>297_bases
ATGACGCCGCAACTCACCTGGACGCGTGAGGCGGACACTCTGGTGCTGGCGGGAGAGCTGGATCAGGACGTGTTGGCGCC
GCTATGGGACGCGCGCGTAGAAGCGATGAATGGCGTTACCCGTATCGACCTGAGCCAGATCTCCAGGGTGGATACGGGGG
GACTGGCGCTGCTGGCGCACCTTGTGAACCAGGCAAAAAAGCAGGGCAATGCCGTGTCGCTGTCTGGCGTTAACGACAAG
GTTTACGCGCTGGCGCAATTATATAACTTGCCCGAAGACGTACTTCCCCGTATGTAA

Upstream 100 bases:

>100_bases
ATGAGTGGAGCGATCTGCTGCGTACTAAAGGCATTGACGGCCTGACCGCACAACTGAAATCTATCTCTCAACAGAAAATT
ACTTTGGACGAGAAACAGTA

Downstream 100 bases:

>100_bases
TGAATGCCGGATGGTTTATCCGGCCTACACTTCGCATGATCCCCGTAGGCCGGATAAGTTGCGTTAGCAGCACCATCCGG
CACTTTTACCGCGCTGATTT

Product: putative anti-sigma factor antagonist

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MTPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDLSQISRVDTGGLALLAHLVNQAKKQGNAVSLSGVNDK
VYALAQLYNLPEDVLPRM

Sequences:

>Translated_98_residues
MTPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDLSQISRVDTGGLALLAHLVNQAKKQGNAVSLSGVNDK
VYALAQLYNLPEDVLPRM
>Mature_97_residues
TPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDLSQISRVDTGGLALLAHLVNQAKKQGNAVSLSGVNDKV
YALAQLYNLPEDVLPRM

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG3113

COG function: function code R; Predicted NTP binding protein (contains STAS domain)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Escherichia coli, GI87082227, Length=97, Percent_Identity=69.0721649484536, Blast_Score=126, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 10685; Mature: 10554

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDLSQISRVDTGGLALLAH
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEECHHHHHCCCCCHHHHHHH
LVNQAKKQGNAVSLSGVNDKVYALAQLYNLPEDVLPRM
HHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure 
TPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDLSQISRVDTGGLALLAH
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEECHHHHHCCCCCHHHHHHH
LVNQAKKQGNAVSLSGVNDKVYALAQLYNLPEDVLPRM
HHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]