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The map label for this gene is hyaA [H]

Identifier: 194737959

GI number: 194737959

Start: 1862751

End: 1863953

Strand: Direct

Name: hyaA [H]

Synonym: SeSA_A1928

Alternate gene names: 194737959

Gene position: 1862751-1863953 (Clockwise)

Preceding gene: 194735574

Following gene: 194737319

Centisome position: 39.56

GC content: 56.69

Gene sequence:

>1203_bases
TTGCTGGCGGAACGTCAACGGACCCGCAAAAGCGCCTTATGCCCCTGGCGGAGCGTGGTGCAAAAAGGAGAAAAAATACG
CGTTATGAATAACGAGGAGACCTTTTATCAAGCCATGCGTCGTAAGGGAGTGACCCGACGCAGCTTTCTCAAATTCTGTA
GCCTTGCCGCCACATCGCTGGGACTGGGCGCCGGAATGACGCCAAAGATCGCCTGGGCGCTGGAGAATAAACCGCGGATT
CCGGTGGTCTGGATTCATGGACTGGAATGCACCTGCTGTACCGAATCCTTTATCCGTTCCTCGCACCCGCTAGCCAAAGA
TGTGATCCTCTCGCTGATTTCCCTCGATTATGACGACACCCTGATGGCCGCCGCCGGCGCACAGGCCGAAGAAGTCTTTG
ACGATATTACCACTCGCTACGCTGGGAAATACATTCTGGCGGTGGAAGGCAATCCACCGTTAGGAGAACAAGGGATGTTC
TGTATCAGCGGCGGTCGCCCGTTTATTGAAAAACTGAAGAAAGCCGCCGCGGGCGCCAGCGCTATTATTGCCTGGGGAAA
CTGCGCTTCCTGGGGTTGCGTCCAGGCCGCCCGCCCCAATCCGACCCAGGCAACGCCTATCGATAAAGTGATCACCGACA
AGCCGATCGTGAAGGTCCCTGGATGTCCGCCAATCCCGGATGTCATGAGCGCCATTATCACCTATATGGTGACGTTTGAT
CGTCTGCCGGAGCTCGATCGCATGGGCCGTCCACTAATGTTCTACGGTCAGCGTATCCACGATAAATGCTACCGCCGCGC
CCATTTTGACGCCGGTGAATTTGTCGAGAGCTGGGATGATGACGCCGCCCGCAAGGGATACTGCCTGTACAAGATGGGCT
GTAAAGGACCAACCACCTATAACGCCTGCTCCTCCACACGCTGGAATGACGGCGTCTCCTTTCCTATCCAGTCCGGTCAC
GGATGTCTGGGATGTTCAGAAAATGGTTTCTGGGATCGCGGCTCGTTTTATAGCCGCGTGGTGGATATTCCCCAGATGGG
TACCCATTCAACCGCCGATACGGTGGGGCTGACCGCGCTGGGCGTGGTCGCGGCGGGCGTTGGCGGTCACGCTGTCGCCA
GCGCGCTCAACCAACGTAAACGCCACAAACAACAGTTAGCGCAAGCCGAACAACAGCCGGACAATGAGGATAAACAGGCA
TGA

Upstream 100 bases:

>100_bases
TTAATCCGATACGCTTTTTTCACATTATTTCTGGCGATATACGCCGGTGCAAAGTGAATCGGGCTCGTTTCCGCGCTCGC
GCGTAACACAATGATTTGCC

Downstream 100 bases:

>100_bases
GTAACCAGTATCAAACCCAGGGTTATACCGTTAACGACGCCGGCCGTCGTCTGATCGTGGACCCGATTACCCGCATCGAA
GGGCATATGCGCTGCGAAGT

Product: hydrogenase-1 small chain

Products: NA

Alternate protein names: HYD1; Membrane-bound hydrogenase 1 small subunit; NiFe hydrogenase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLAERQRTRKSALCPWRSVVQKGEKIRVMNNEETFYQAMRRKGVTRRSFLKFCSLAATSLGLGAGMTPKIAWALENKPRI
PVVWIHGLECTCCTESFIRSSHPLAKDVILSLISLDYDDTLMAAAGAQAEEVFDDITTRYAGKYILAVEGNPPLGEQGMF
CISGGRPFIEKLKKAAAGASAIIAWGNCASWGCVQAARPNPTQATPIDKVITDKPIVKVPGCPPIPDVMSAIITYMVTFD
RLPELDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVESWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGH
GCLGCSENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGVVAAGVGGHAVASALNQRKRHKQQLAQAEQQPDNEDKQA

Sequences:

>Translated_400_residues
MLAERQRTRKSALCPWRSVVQKGEKIRVMNNEETFYQAMRRKGVTRRSFLKFCSLAATSLGLGAGMTPKIAWALENKPRI
PVVWIHGLECTCCTESFIRSSHPLAKDVILSLISLDYDDTLMAAAGAQAEEVFDDITTRYAGKYILAVEGNPPLGEQGMF
CISGGRPFIEKLKKAAAGASAIIAWGNCASWGCVQAARPNPTQATPIDKVITDKPIVKVPGCPPIPDVMSAIITYMVTFD
RLPELDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVESWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGH
GCLGCSENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGVVAAGVGGHAVASALNQRKRHKQQLAQAEQQPDNEDKQA
>Mature_400_residues
MLAERQRTRKSALCPWRSVVQKGEKIRVMNNEETFYQAMRRKGVTRRSFLKFCSLAATSLGLGAGMTPKIAWALENKPRI
PVVWIHGLECTCCTESFIRSSHPLAKDVILSLISLDYDDTLMAAAGAQAEEVFDDITTRYAGKYILAVEGNPPLGEQGMF
CISGGRPFIEKLKKAAAGASAIIAWGNCASWGCVQAARPNPTQATPIDKVITDKPIVKVPGCPPIPDVMSAIITYMVTFD
RLPELDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVESWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGH
GCLGCSENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGVVAAGVGGHAVASALNQRKRHKQQLAQAEQQPDNEDKQA

Specific function: This Is One Of Three E.Coli Hydrogenases Synthesized In Response To Different Physiological Conditions. Hyd1 Is Believed To Have A Role In Hydrogen Cycling During Fermentative Growth. [C]

COG id: COG1740

COG function: function code C; Ni,Fe-hydrogenase I small subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family [H]

Homologues:

Organism=Escherichia coli, GI1787206, Length=372, Percent_Identity=92.2043010752688, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1789371, Length=329, Percent_Identity=39.209726443769, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR001821
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.12.99.6 [H]

Molecular weight: Translated: 43883; Mature: 43883

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAERQRTRKSALCPWRSVVQKGEKIRVMNNEETFYQAMRRKGVTRRSFLKFCSLAATSL
CCCCHHHHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GLGAGMTPKIAWALENKPRIPVVWIHGLECTCCTESFIRSSHPLAKDVILSLISLDYDDT
CCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
LMAAAGAQAEEVFDDITTRYAGKYILAVEGNPPLGEQGMFCISGGRPFIEKLKKAAAGAS
HHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCC
AIIAWGNCASWGCVQAARPNPTQATPIDKVITDKPIVKVPGCPPIPDVMSAIITYMVTFD
EEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHH
RLPELDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVESWDDDAARKGYCLYKMGCKGPTTY
HCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCEEEEEECCCCCCCC
NACSSTRWNDGVSFPIQSGHGCLGCSENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTAL
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
GVVAAGVGGHAVASALNQRKRHKQQLAQAEQQPDNEDKQA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLAERQRTRKSALCPWRSVVQKGEKIRVMNNEETFYQAMRRKGVTRRSFLKFCSLAATSL
CCCCHHHHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GLGAGMTPKIAWALENKPRIPVVWIHGLECTCCTESFIRSSHPLAKDVILSLISLDYDDT
CCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
LMAAAGAQAEEVFDDITTRYAGKYILAVEGNPPLGEQGMFCISGGRPFIEKLKKAAAGAS
HHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCC
AIIAWGNCASWGCVQAARPNPTQATPIDKVITDKPIVKVPGCPPIPDVMSAIITYMVTFD
EEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHH
RLPELDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVESWDDDAARKGYCLYKMGCKGPTTY
HCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCEEEEEECCCCCCCC
NACSSTRWNDGVSFPIQSGHGCLGCSENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTAL
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
GVVAAGVGGHAVASALNQRKRHKQQLAQAEQQPDNEDKQA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA