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The map label for this gene is engD [H]

Identifier: 194737864

GI number: 194737864

Start: 1857843

End: 1858934

Strand: Direct

Name: engD [H]

Synonym: SeSA_A1923

Alternate gene names: 194737864

Gene position: 1857843-1858934 (Clockwise)

Preceding gene: 194737518

Following gene: 194735574

Centisome position: 39.45

GC content: 53.21

Gene sequence:

>1092_bases
ATGGGATTCAAATGCGGTATCGTCGGTCTGCCCAACGTCGGGAAATCCACCCTGTTCAACGCGCTGACAAAAGCCGGTAT
TGAAGCGGCAAACTTTCCGTTCTGCACTATCGAACCGAATACCGGTGTCGTGCCGATGCCCGATCCGCGTCTGGACCAGT
TGGCTGAGATTGTTAAACCGCAACGCATTCTACCAACCACGATGGAGTTCGTGGATATCGCCGGTCTGGTGAAAGGCGCG
TCCAAAGGCGAAGGGTTGGGTAACCAGTTCCTGACCAATATCCGTGAAACCGAAGCTATCGGTCACGTGGTTCGCTGCTT
TGAGAACGACAATATCATCCACGTGGCCGGTAAAGTAAATCCGGCAGAAGATATTGATGTTATCAATACCGAACTGGCGC
TGGCTGACCTCGATACCTGCGAGCGCGCTATCCATCGCGTACAGAAGAAAGCCAAAGGCGGCGATAAAGACGCCAAAGCG
GAACTGGCCGCGCTGGAAAAATGCCTGCCGCACCTGGCCGAAGCGGGGATGCTGCGTTCGCTGGACCTGACGGACGAAGA
TAAAGCGGCTATCCGTTATTTAAGCTTCCTGACGCTGAAGCCGACGATGTATATCGCTAACGTCAATGAAGACGGTTTTG
AAAATAACCCGTATCTCGACCAGGTTCGCGAAATCGCCGCCAAAGAAGGTTCGGTCGTGGTTCCGGTGTGTGCCGCCGTC
GAAGCTGATATTGCTGAGCTGGATGATGACGAGCGCGACGAATTTATGGCTGAACTGGGTCTGGAAGAACCGGGGCTGAA
CCGCGTTATTCGCGCAGGTTATCGCCTGCTGAACCTCCAGACCTACTTTACCGCCGGGGTGAAAGAAGTTCGCGCATGGA
CCATTCCGGTTGGCGCAACCGCGCCGCAGGCGGCAGGTAAAATCCATACCGACTTCGAAAAAGGCTTTATCCGCGCCCAA
ACTATCGCCTTTGACGACTTTATTACCTATAAAGGTGAACAAGGCGCGAAAGAAGCCGGTAAGATGCGAGCGGAAGGCAA
AGATTACATCGTTAAAGATGGCGATATAATGAACTTCCTGTTCAACGTCTAA

Upstream 100 bases:

>100_bases
TTTTTGCCGCACGCCGTGTATAATAGGCGAAGTTATTTCCATTTCTGCAATCTGTTTTCTATAACAGGTTGATTATTAAG
ATATTAAGGTGAGTTAAATC

Downstream 100 bases:

>100_bases
ATAACATTTGTTGTCTCATGAGGTTTTGCTGAATCTCATGACAGCGGTAAACCCTATAAAATCCACGCCATTGCGTGGAT
TTTTCATTTCATAGTATCTC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGA
SKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVNPAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
ELAALEKCLPHLAEAGMLRSLDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAV
EADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRLLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQ
TIAFDDFITYKGEQGAKEAGKMRAEGKDYIVKDGDIMNFLFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGA
SKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVNPAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
ELAALEKCLPHLAEAGMLRSLDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAV
EADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRLLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQ
TIAFDDFITYKGEQGAKEAGKMRAEGKDYIVKDGDIMNFLFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGAS
KGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVNPAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKAE
LAALEKCLPHLAEAGMLRSLDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAVE
ADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRLLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQT
IAFDDFITYKGEQGAKEAGKMRAEGKDYIVKDGDIMNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=44.1734417344173, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=39.2070484581498, Blast_Score=155, Evalue=5e-38,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=95.0413223140496, Blast_Score=712, Evalue=0.0,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=32.2834645669291, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=40.5479452054795, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=38.8586956521739, Blast_Score=252, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=382, Percent_Identity=35.0785340314136, Blast_Score=196, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6321649, Length=145, Percent_Identity=37.2413793103448, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=43.7158469945355, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=43.7158469945355, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=43.7158469945355, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=41.4634146341463, Blast_Score=247, Evalue=7e-66,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39603; Mature: 39471

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCC
QRILPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVN
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKAELAALEKCLPHLAEAGMLRS
CHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
LDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAV
CCCCCCHHHHHHHHHHHEECCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHH
EADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRLLNLQTYFTAGVKEVRAWTIPVGAT
HHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
APQAAGKIHTDFEKGFIRAQTIAFDDFITYKGEQGAKEAGKMRAEGKDYIVKDGDIMNFL
CCHHCCCCCCHHHHCCEEEEEEEEHHHEEECCCCCHHHHHHHHCCCCCEEEECCHHHHHH
FNV
HCC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCC
QRILPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVAGKVN
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKAELAALEKCLPHLAEAGMLRS
CHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
LDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAV
CCCCCCHHHHHHHHHHHEECCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHH
EADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRLLNLQTYFTAGVKEVRAWTIPVGAT
HHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
APQAAGKIHTDFEKGFIRAQTIAFDDFITYKGEQGAKEAGKMRAEGKDYIVKDGDIMNFL
CCHHCCCCCCHHHHCCEEEEEEEEHHHEEECCCCCHHHHHHHHCCCCCEEEECCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]