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The map label for this gene is mppA [H]

Identifier: 194737751

GI number: 194737751

Start: 1745172

End: 1746785

Strand: Reverse

Name: mppA [H]

Synonym: SeSA_A1804

Alternate gene names: 194737751

Gene position: 1746785-1745172 (Counterclockwise)

Preceding gene: 194738379

Following gene: 194737898

Centisome position: 37.09

GC content: 48.82

Gene sequence:

>1614_bases
ATGAGGCATTCTGTTTCAGTAACCTGTTGTGCGCTGTTGGTTAGCAGCTTTTCCCTGGCATATGCTGCGGATGTTCCCGG
CGGAACGGTACTGGCAGAGAAACAAGAACTGGTGCGTCATATCAAAGATGAGCCCGCTTCGTTAGATCCAGCGAAAGCCG
TTGGGCTGCCTGAAATTCAGGTGATCCGCGATCTGTTTGAAGGGCTGGTTAACCAGAACGAAAAGGGTGAAATTATCCCT
GGCGTCGCCAGCCAGTGGAAGAGCAATGATAATCGTATCTGGACGTTTACGTTGCGGGATAATGCGCAATGGGCCGATGG
AACGCCGGTGACCGCCCAGGATTTTGTCTATAGCTGGCAACGTCTCGTTGATCCCAAAACGCTTTCCCCCTTCGCCTGGT
TTGCCGCTCTGGCTGGCATCACTAATGCGCAAGCCATTATCGACGGTAAAGCCACGCCGGATCAGCTTGGCGTCAGTGCC
GTGGACGCGCACACTTTGCGTATTCAGCTTGACAAGCCGTTGCCCTGGTTTGCCAGTCTGACCGCCAGTTTTGCCTTTTA
TCCGGTCCAAAAAGCGAATGTTGAAAGCGGTAAAGACTGGATGAAGCCGGGAAAACTGATCGGCAATGGCGCGTATGTGC
TTAAAGAGCGCGTGGTAAATGAAAAACTGGTGGTCGTGCCTAATACGCATTACTGGGATAACGCGAAAACGGTACTGCAA
AAAGTGACATTTTTACCCATTAACCAGGAGTCGGCTGCGACGAAACGTTATCTTGCCGGTGATATTGATATCACCGAATC
TTTCCCTAAAAATATGTACCAGAAATTATTGAAGGATATTCCAGGGCAAGTTTATACGCCGCCGCAATTAGGGACTTATT
ATTATGCGTTTAATACGCAGAAAGGGCCGACGGCGGATTCCCGCGTTCGTCTGGCGCTAAGTATGACTATTGATCGCCGT
TTGATGGCGGAAAAAGTCTTAGGTACCGGTGAAAAACCGGCCTGGCATTTTACACCGGATGTCACGGCAGGATTTAAGCC
CGATCCTTCACCGTTTGAACAAATGAGCCAGGAAGAACTTAATGCCCAGGCGAAAACATTGCTGCGTGCAGCAGGCTACG
GATCGCAGAAGCCGCTTAAATTAACCCTGCTTTACAATACCTCAGAAAACCATCAGAAAATCGCGATTGCGGTGGCGTCA
ATGTGGAAGAAAAATCTGGGGGTGGATGTGAAATTGCAAAACCAGGAGTGGAAAACGTATATCGACAGTCGGAATACCGG
TAATTTTGATGTTATTCGCGCCTCCTGGATGGGTGATTACAACGAACCGTCGACTTTCTTATCCTTATTAACGTCCACGC
ATACGGGGAATATTTCACGCTTTACTAATCCGACTTATGACAAAATCCTGACGCAAGCGACGATGGAAAATACCGCCGAA
GCGCGTAATGCGGATTACAATGCAGCGGAGAAAATTTTAACGGAACAAGCGCCTATAGCGCCTATTTATCAGTATACCAA
TGGCCGGTTAATTAAACCGTGGGTAAAGGGTTACCCCATTACTAACCCGGAAGATGTGGCCTATAGCCGTACGATGTATA
TCGTGAAGCACTGA

Upstream 100 bases:

>100_bases
TGTATGGCGCGATATCAACTTTCTGGCGGAAGATAATTGCATTTCTTTCTGCTGAAACAAATAATTACGTTGTCATTTAA
CTCATCTTTGAGGAACTTCT

Downstream 100 bases:

>100_bases
TGCGTACTGGTTTCTTGTTAACGCAAGGTAGCCACGCCCGCCGCCTGATGCTGGCAGAAGGCATGGGAATTAAGCGATCG
CCTGATGCCGCCGTTCTCAT

Product: periplasmic murein peptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDNAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDGKATPDQLGVSA
VDAHTLRIQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWMGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH

Sequences:

>Translated_537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDNAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDGKATPDQLGVSA
VDAHTLRIQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWMGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
>Mature_537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDNAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDGKATPDQLGVSA
VDAHTLRIQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWMGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=92.9236499068901, Blast_Score=1049, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=539, Percent_Identity=48.2374768089054, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=43.1001890359168, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1787762, Length=541, Percent_Identity=28.6506469500924, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789887, Length=486, Percent_Identity=24.4855967078189, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789966, Length=466, Percent_Identity=22.7467811158798, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59922; Mature: 59922

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDNAQWADGTPVTAQDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGITNAQAIIDGKATPDQLGVSAVDAHTLRIQLDKPLPWFASL
HHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCCEEECEEEEEEEECCCCCHHHHH
TASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
HHHHEEEECCCCCCCCCHHHCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
HHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEEL
CCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTGNFDVIRASWMGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
HCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
HCCCCCHHHHHHHHCCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDNAQWADGTPVTAQDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGITNAQAIIDGKATPDQLGVSAVDAHTLRIQLDKPLPWFASL
HHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCCEEECEEEEEEEECCCCCHHHHH
TASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
HHHHEEEECCCCCCCCCHHHCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
HHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPAWHFTPDVTAGFKPDPSPFEQMSQEEL
CCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTGNFDVIRASWMGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
HCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
HCCCCCHHHHHHHHCCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]