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The map label for this gene is sseC [H]

Identifier: 194737731

GI number: 194737731

Start: 1448902

End: 1450356

Strand: Direct

Name: sseC [H]

Synonym: SeSA_A1496

Alternate gene names: 194737731

Gene position: 1448902-1450356 (Clockwise)

Preceding gene: 194734854

Following gene: 194738310

Centisome position: 30.77

GC content: 46.12

Gene sequence:

>1455_bases
ATGAATCGAATTCACAGTAATAGCGACAGCGCCGCAGGAGTAACCGCCTTAACACATCATCACTTAAGCAATGTCAGTTG
CGTTTCCTCGGGTTCGCTGGGAAAGCGCCAGCATCGTGTGAATTCTACTTTTGGCGATGGCAACGCCGCGTGCCTGTTAT
CAGGGAAAATTAGTCTTCAGGAGGCAAGCAATGCGTTGAAGCAACTGCTTGATGCCGTACCCGGAAATCATAAGCGTCCA
TCATTGCCTGACTTTTTGCAGACCAATCCCGCGGTTTTATCAATGTTGATGACGACATTAATACTCAGCGTTTTTGGTAA
TAACGCTCAATCGTTATGCCAACAGCTTGAGCGGGCAACTGAGGTGCAAAATGCATTACGTGATAAGCAGGTAAAGGAGT
ATCAGGAGCAGATCCAGAAAGCGATAGAGCAGGAGGATAAAGCGCGTAAAGCGGGCATTTTTGGCGCTATTTTTGACTGG
ATTACCGGCATATTTGAAACTGTGATTGGCGCCTTAAAAGTTGTGGAGGGTTTTCTGTCCGGTAATCCCGCAGAAATGGC
TAGCGGCGTAGCTTATATAGCCGCAGGTTGTGCAGGAATGGTTAAAGCCGGAGCCGAAACGGCAATGATGTGCGGTGCTG
ACCACGATACCTGTCAGGCAATTATTGACGTGACAAGTAAGATTCAATTTGGTTGTGAAGCCGTCGCGCTGGCACTGGAT
GTTTTCCAGATTGGCCGTGCTTTTATGGCGACGAGAGGTTTATCTGGCGCAGCTGCAAAAGTGCTTGACTCCGGTTTTGG
CGAGGAAGTGGTTGAGCGTATGGTAGGTGCAGGGGAAGCAGAAATAGAGGAGTTGGCTGAAAAGTTTGGCGAAGAAGTGA
GCGAAAGTTTTTCCAAACAATTTGAGCCGCTTGAACGTGAAATGGCTATGGCGAATGAGATGGCAGAGGAGGCTGCCGAG
TTTTCTCGTAACGTAGAAAATAATATGACGCGAAGCGCGGGAAAAAGCTTTACGAAAGAGGGGGTGAAAGCCATGGCAAA
AGAAGCGGCAAAAGAAGCCCTGGAAAAATGTGTGCAAGAAGGTGGAAAGTTCCTGTTAAAAAAATTCCGTAATAAAGTTC
TCTTCAATATGTTCAAAAAAATCCTGTATGCCTTACTGAGGGATTGTTCATTTAAAGGCTTACAGGCTATCAGATGTGCA
ACCGAGGGCGCCAGTCAGATGAATACTGGCATGGTTAACACAGAAAAAGCGAAGATCGAAAAGAAAATAGAGCAATTAAT
AACTCAGCAACGGTTTCTGGATTTCATAATGCAACAAACGGAAAACCAGAAAAAGATAGAACAAAAACGCTTAGAGGAGC
TTTATAAGGGGAGCGGTGCCGCGCTTAGAGATGTATTAGATACCATTGATCACTATAGTAGCGTTCAGGCGAGAATAGCT
GGCTATCGCGCTTAA

Upstream 100 bases:

>100_bases
TAAAGGCCGTGGTGCGTATTTGCGGCGAGGTCAGTGAACATCAAATTCTCCGACAGCGTGCAGAAAAGATGTTACAGCAA
CTTTCTGACAGGAGCTAAAA

Downstream 100 bases:

>100_bases
TCTGAGGATAAAAATATGGAAGCGAGTAACGTAGCACTGGTATTACCAGCGCCTTCCTTGTTAACACCTTCTTCCACTCC
ATCTCCCTCCGGGGAGGGAA

Product: translocation machinery component

Products: NA

Alternate protein names: Secretion system effector C [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRP
SLPDFLQTNPAVLSMLMTTLILSVFGNNAQSLCQQLERATEVQNALRDKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
ITGIFETVIGALKVVEGFLSGNPAEMASGVAYIAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALD
VFQIGRAFMATRGLSGAAAKVLDSGFGEEVVERMVGAGEAEIEELAEKFGEEVSESFSKQFEPLEREMAMANEMAEEAAE
FSRNVENNMTRSAGKSFTKEGVKAMAKEAAKEALEKCVQEGGKFLLKKFRNKVLFNMFKKILYALLRDCSFKGLQAIRCA
TEGASQMNTGMVNTEKAKIEKKIEQLITQQRFLDFIMQQTENQKKIEQKRLEELYKGSGAALRDVLDTIDHYSSVQARIA
GYRA

Sequences:

>Translated_484_residues
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRP
SLPDFLQTNPAVLSMLMTTLILSVFGNNAQSLCQQLERATEVQNALRDKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
ITGIFETVIGALKVVEGFLSGNPAEMASGVAYIAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALD
VFQIGRAFMATRGLSGAAAKVLDSGFGEEVVERMVGAGEAEIEELAEKFGEEVSESFSKQFEPLEREMAMANEMAEEAAE
FSRNVENNMTRSAGKSFTKEGVKAMAKEAAKEALEKCVQEGGKFLLKKFRNKVLFNMFKKILYALLRDCSFKGLQAIRCA
TEGASQMNTGMVNTEKAKIEKKIEQLITQQRFLDFIMQQTENQKKIEQKRLEELYKGSGAALRDVLDTIDHYSSVQARIA
GYRA
>Mature_484_residues
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRP
SLPDFLQTNPAVLSMLMTTLILSVFGNNAQSLCQQLERATEVQNALRDKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
ITGIFETVIGALKVVEGFLSGNPAEMASGVAYIAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALD
VFQIGRAFMATRGLSGAAAKVLDSGFGEEVVERMVGAGEAEIEELAEKFGEEVSESFSKQFEPLEREMAMANEMAEEAAE
FSRNVENNMTRSAGKSFTKEGVKAMAKEAAKEALEKCVQEGGKFLLKKFRNKVLFNMFKKILYALLRDCSFKGLQAIRCA
TEGASQMNTGMVNTEKAKIEKKIEQLITQQRFLDFIMQQTENQKKIEQKRLEELYKGSGAALRDVLDTIDHYSSVQARIA
GYRA

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells [H]

COG id: COG5613

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006972 [H]

Pfam domain/function: PF04888 SseC [H]

EC number: NA

Molecular weight: Translated: 52730; Mature: 52730

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609 [H]