| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is rlmL [H]
Identifier: 194737689
GI number: 194737689
Start: 1108772
End: 1110880
Strand: Direct
Name: rlmL [H]
Synonym: SeSA_A1123
Alternate gene names: 194737689
Gene position: 1108772-1110880 (Clockwise)
Preceding gene: 194734123
Following gene: 194737532
Centisome position: 23.55
GC content: 54.95
Gene sequence:
>2109_bases ATGAATTCTCTGTTTGCCAGTACGGCCCGCGGGCTGGAAGAGCTGTTAAAAACTGAACTGGAAAAACTGGGCGCCGTAGG GTGTCAGGTTGTTCAGGGTGGGGTCCATTTTCAGGGCGACACGCGGCTTATTTACCAGAGCCTGATGTGGAGCCGCCTGG CCTCGCGTATTATCCTGCCGATGGGTGAGTGCAAGGTCTACAGCGATCTCGATCTTTACCTCGGCGTTCAGGCGATAAAC TGGACAGAGATTTTTAATCCTGGCGCGACGTTTGCGGTGCATTTCAGCGGCCTGAACGACACCATCCGTAATAGTCAGTA TGGCGCGATGAAAGTTAAAGACGCGATTGTCGATGCATTTACGCGGAAAAATCTTCCGCGTCCAAATGTGGACCGCGAAT CACCGGACCTCCGTATTAACGTCTGGCTGAATAAAGAAACTGCCAGCATTGCGCTGGATCTCAGTGGTGATGGCCTGCAC CTGCGCGGTTATCGCGATCGCACCGGGCTGGCGCCAATTAAAGAGACGCTGGCGGCAGCGATTGTTATGCGTTCCGGCTG GCAACCAGGAACCCCGCTGCTCGACCCTATGTGTGGTTCGGGGACTCTGTTGATTGAGGCCGCGATGTGGGCGACCGATC GCGCGCCGGGACTGCACCGTGGTCACTGGGGATTTAGCGGCTGGGCGCAGCATGACGAGGCTATCTGGCAGGAAGTGAAA GCCGAAGCGCAGACCCGGGCGCGTAAGGGGCTGGCGGAGTATTCCTCTCATTTCTACGGTTCCGACAGCGATGCGCGCGT CATTGAGCGGGCGCGCAGCAACGCCCGTCGCGCCGGTATCGGGGAGCTTATCACCTTTGAAGTGAAAGATGTGGCGCAAC TGAGTAATCCATTGCCGAAAGGCCCGTATGGTACGGTGATCAGTAACCCGCCTTACGGCGAACGTCTGGACAGCGAACCG GCGCTGATTGCGTTGCACAGCCTGCTGGGCCGTACCATGAAAAATCAGTTTGGCGGCTGGAACCTGTCGCTGTTCAGCGC TTCGCCCGATTTGCTGGGCAGCCTGCAATTGCGTGCCGACAAACAGTTTAAAGCCAAGAATGGCCCGCTGGACTGCGTGC AGAAAAACTATCATATTGCGGAAACCACGGCGGACAGTAAACCGGCGACGGTGGCGGAAGATTACGCTAATCGCCTGCGT AAAAATCTTAAAAAGCTGGAGAAATGGGCGCGCCAGGAAGGGATTGAATGCTATCGCTTGTATGATGCCGACCTGCCGGA ATATAACGTGGCGGTAGACCGTTACGGCGACTGGGCGGTGATTCAGGAATATGCGCCGCCGAAAACGGTGGATGCGCAAA AAGCGCGGCAACGTCTGTTCGATATTATTGCGGCAACCTTGTCAGTGCTCGGTATTCCGCCGAATAAACTGGTGTTAAAA ACCCGTGAACGACAAAAAGGAAAAAACCAGTATCAGAAAATGAGCGAGAAGGGCGAGTTCCTTGAGGTCAGCGAATATAA TGCGCGCTTATGGGTAAATCTGACGGATTATCTCGACACCGGTCTGTTCCTCGATCACCGTATTGCCCGCAGAATGCTGG GAGAAATGAGCAAAGGCAAAGATTTCCTGAATCTCTTTTCTTATACCGGCAGCGCCAGCGTACATGCGGGTCTGGGCGGC GCGCGCAGCACCACAACGGTGGATATGTCCCGCACCTATCTGGAGTGGGCCGAACGTAATTTGCGTCTGAACGGACTGAG TGGCCGCGCGCATCGCCTGATTCAGGCCGACTGCCTGGGCTGGCTGCGCGAGGCGAATGAACAGTTCGATTTGATCTTTA TCGATCCGCCGACGTTCTCTAACTCAAAACGTATGGAAGAGTCGTTTGATGTTCAGCGCGATCATGTCGCGTTAATGAAA GATTTAAAACGCCTGCTGCGTAAAGGCGGCACCATCATGTTCTCAAATAATAAGCGCGGATTCCGTATGGATCTGGAAGG GCTGGCGGAACTGGGGCTTACCGCACAAGAAATTACGCAAAAAACGCTCTCCCCGGATTTTGCCCGTAACCGTCAGATTC ATAACTGCTGGCTGATCCGCGCCGCCTGA
Upstream 100 bases:
>100_bases ACCGTACAGTCCCTCAAATGAAAATAAGCCTTCAACTTTATGACATGGGCGTGAGATTAGCTATAATGCGCAACAATTTT CTTAGCGTAAAAGTGACAAT
Downstream 100 bases:
>100_bases AAGGAAAAGTAAATGTCATTAATCAGTATGCATGGCGCATGGCTGTCGTTCAGCGACGCGCCGCTTCTCGATAACGCAGA GTTGCATATCGAAGATAACG
Product: 23S rRNA m(2)G2445 methyltransferase
Products: NA
Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]
Number of amino acids: Translated: 702; Mature: 702
Protein sequence:
>702_residues MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAIN WTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLH LRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDEAIWQEVK AEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEP ALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLR KNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLK TRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGG ARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMK DLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA
Sequences:
>Translated_702_residues MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAIN WTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLH LRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDEAIWQEVK AEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEP ALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLR KNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLK TRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGG ARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMK DLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA >Mature_702_residues MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILPMGECKVYSDLDLYLGVQAIN WTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLH LRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDEAIWQEVK AEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEP ALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLR KNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLK TRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGG ARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMK DLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA
Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]
COG id: COG0116
COG function: function code L; Predicted N6-adenine-specific DNA methylase
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 THUMP domain [H]
Homologues:
Organism=Escherichia coli, GI1787181, Length=702, Percent_Identity=92.1652421652422, Blast_Score=1340, Evalue=0.0, Organism=Escherichia coli, GI145693111, Length=241, Percent_Identity=29.045643153527, Blast_Score=87, Evalue=5e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002052 - InterPro: IPR002296 - InterPro: IPR000241 - InterPro: IPR017244 - InterPro: IPR019614 - InterPro: IPR004114 [H]
Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]
EC number: =2.1.1.173 [H]
Molecular weight: Translated: 78820; Mature: 78820
Theoretical pI: Translated: 9.10; Mature: 9.10
Prosite motif: PS51165 THUMP ; PS00092 N6_MTASE ; PS01261 UPF0020
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILP CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEECCCHHHHHHHHHHHHHHHHHCCC MGECKVYSDLDLYLGVQAINWTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAF CCCCEEECCCEEEEEEEEECHHHHCCCCCEEEEEECCCCHHHCCCCCCCHHHHHHHHHHH TRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLHLRGYRDRTGLAPIKETLAAA HHCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH IVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDEAIWQEVK HHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH AEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPK HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCC GPYGTVISNPPYGERLDSEPALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRAD CCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCEEECCC KQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLRKNLKKLEKWARQEGIECYRL CCHHCCCCCHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE YDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLK ECCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE TRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGK CHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCH DFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLG HHHHHHHCCCCCCEECCCCCCCCCEEEHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHH WLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRG HHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCC FRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA EEECHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEC >Mature Secondary Structure MNSLFASTARGLEELLKTELEKLGAVGCQVVQGGVHFQGDTRLIYQSLMWSRLASRIILP CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEECCCHHHHHHHHHHHHHHHHHCCC MGECKVYSDLDLYLGVQAINWTEIFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAF CCCCEEECCCEEEEEEEEECHHHHCCCCCEEEEEECCCCHHHCCCCCCCHHHHHHHHHHH TRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLHLRGYRDRTGLAPIKETLAAA HHCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH IVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDEAIWQEVK HHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH AEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPK HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCC GPYGTVISNPPYGERLDSEPALIALHSLLGRTMKNQFGGWNLSLFSASPDLLGSLQLRAD CCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCEEECCC KQFKAKNGPLDCVQKNYHIAETTADSKPATVAEDYANRLRKNLKKLEKWARQEGIECYRL CCHHCCCCCHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE YDADLPEYNVAVDRYGDWAVIQEYAPPKTVDAQKARQRLFDIIAATLSVLGIPPNKLVLK ECCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE TRERQKGKNQYQKMSEKGEFLEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGEMSKGK CHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCH DFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLG HHHHHHHCCCCCCEECCCCCCCCCEEEHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHH WLREANEQFDLIFIDPPTFSNSKRMEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRG HHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCC FRMDLEGLAELGLTAQEITQKTLSPDFARNRQIHNCWLIRAA EEECHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA