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The map label for this gene is spaP [H]

Identifier: 194737581

GI number: 194737581

Start: 2940867

End: 2941541

Strand: Reverse

Name: spaP [H]

Synonym: SeSA_A3043

Alternate gene names: 194737581

Gene position: 2941541-2940867 (Counterclockwise)

Preceding gene: 194738216

Following gene: 194737177

Centisome position: 62.47

GC content: 41.48

Gene sequence:

>675_bases
ATGGGGAATGATATCTCATTAATTGCCTTACTGGCATTTTCCACCCTGTTGCCATTTATTATTGCGTCAGGAACCTGTTT
CGTTAAATTTTCTATTGTATTTGTCATGGTGCGTAACGCCCTGGGATTGCAGCAGATACCTTCAAATATGACGCTTAACG
GCGTCGCATTGCTGCTTTCTATGTTTGTTATGTGGCCCATAATGCATGATGCCTACGTCTATTTTGAGGACGAAGATGTC
ACCTTTAATGATATTTCGTCATTAAGTAAACACGTTGATGAAGGTCTGGATGGTTATCGCGATTATCTGATCAAATATTC
AGATCGCGAGTTAGTTCAGTTTTTTGAAAACGCGCAACTGAAGCGTCAGTATGGAGAAGAGACCGAGACGGTAAAGCGTG
ACAAAGATGAAATTGAAAAACCATCAATATTTGCGTTATTACCTGCTTATGCGCTGAGCGAAATAAAAAGCGCGTTTAAA
ATTGGTTTTTATCTCTATTTGCCCTTTGTTGTCGTCGACCTAGTGGTATCCAGCGTGCTACTGGCGCTGGGGATGATGAT
GATGAGTCCGGTGACGATATCTACACCTATTAAGCTGGTGCTTTTTGTCGCGCTTGATGGCTGGACATTACTGTCTAAGG
GATTGATTTTACAGTATATGGACATTGCAACATGA

Upstream 100 bases:

>100_bases
GAAATTATGGCGAATGGTGTTTTGCTGGGTAATGGCGAACTGGTACAGATGAATGACACCTTAGGCGTTGAGATCCATGA
ATGGCTGAGCGAGTCTGGTA

Downstream 100 bases:

>100_bases
CATCATTACGAGACGGGATAGTTAAATGGATGATTTAGTGTTTGCAGGTAATAAGGCGCTCTATCTTGTTTTGATCCTGT
CAGGGTGGCCGACGATTGTC

Product: surface presentation of antigens protein SpaP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDV
TFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT

Sequences:

>Translated_224_residues
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDV
TFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
>Mature_223_residues
GNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDVT
FNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKI
GFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=206, Percent_Identity=37.8640776699029, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 25232; Mature: 25101

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS01060 FLIP_1 ; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL
HHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL
HHHHCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
HHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL
HHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL
HHHHCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
HHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7638176; 11677608; 12644504 [H]