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The map label for this gene is znuB [H]

Identifier: 194737285

GI number: 194737285

Start: 1966753

End: 1967538

Strand: Direct

Name: znuB [H]

Synonym: SeSA_A2047

Alternate gene names: 194737285

Gene position: 1966753-1967538 (Clockwise)

Preceding gene: 194738340

Following gene: 194734959

Centisome position: 41.77

GC content: 55.22

Gene sequence:

>786_bases
ATGATTGAATTATTACTGCCCGGCTGGCTGGCCGGGATGATGCTGGCCTGCGCCGCTGGTCCTTTGGGCTCATTTGTGGT
CTGGCGTCGGATGTCCTATTTTGGCGATACGCTGGCTCACGCGTCGCTTCTGGGCGTGGCGTTTGGCCTGTTGCTGGACG
TTAACCCCTTTTATGCGGTAATCGCCGTTACGCTGCTGCTGGCCGCCGGTCTGGTATGGCTGGAGAAACGCCCTCACCTC
GCGATTGATACCTTACTGGGCATTATGGCGCACAGCGCCTTATCTTTAGGACTGGTCGTGGTCAGCCTGATGTCCAATGT
CCGCGTTGATTTAATGGCTTATCTGTTTGGCGATTTGCTGGCCGTCACGCCGGAAGATCTTATCTCGATCGCTATTGGGG
TCGTTATTGTGCTGGCCATTCTCTTCTGGCAGTGGCGCAACTTGCTGTCAATGACTATCAGTCCGGATCTTGCCTTTGTC
GATGGCGTGAAGTTACAGCGCGTGAAGCTGCTATTGATGCTGGTAACGGCGTTAACTATCGGCGTGGCGATGAAGTTTGT
CGGAGCGCTGATCATTACGTCGCTACTGATTATCCCCGCCGCAACCGCGCGTCGCTTTGCCCGTACGCCGGAACAGATGG
CGGGCGTCGCCGTTGGTGTAGGTATGATAGCGGTTACAGGTGGACTGACCTTCTCAGCCTTTTATGATACCCCGGCAGGG
CCATCCGTAGTGCTGTGTGCCGCGCTGCTGTTTATCTTCAGTATGATGAAAAAGCAGGCAAGCTAA

Upstream 100 bases:

>100_bases
GCCCGCGAGGCGCGGAGCAATTAGGGATTTATCGCCATCATCATAATCATCGCCACGATTTACAGGGTCGTATTGTACTG
CGCCGGGGAAATGGTCACTC

Downstream 100 bases:

>100_bases
GCGTGTGTTGCCCGGTGGCGCTGCGCTTACCGGGCCTACAAAATCGCCCAGGTCTGATGAGCGCAGCGACTTCAGGCGCT
AAGGCATCTCTGGCGGCGTG

Product: high-affinity zinc transporter membrane component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAVIAVTLLLAAGLVWLEKRPHL
AIDTLLGIMAHSALSLGLVVVSLMSNVRVDLMAYLFGDLLAVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFV
DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVGVGMIAVTGGLTFSAFYDTPAG
PSVVLCAALLFIFSMMKKQAS

Sequences:

>Translated_261_residues
MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAVIAVTLLLAAGLVWLEKRPHL
AIDTLLGIMAHSALSLGLVVVSLMSNVRVDLMAYLFGDLLAVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFV
DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVGVGMIAVTGGLTFSAFYDTPAG
PSVVLCAALLFIFSMMKKQAS
>Mature_261_residues
MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAVIAVTLLLAAGLVWLEKRPHL
AIDTLLGIMAHSALSLGLVVVSLMSNVRVDLMAYLFGDLLAVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFV
DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVGVGMIAVTGGLTFSAFYDTPAG
PSVVLCAALLFIFSMMKKQAS

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=261, Percent_Identity=96.1685823754789, Blast_Score=489, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 27776; Mature: 27776

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAV
CCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IAVTLLLAAGLVWLEKRPHLAIDTLLGIMAHSALSLGLVVVSLMSNVRVDLMAYLFGDLL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFVDGVKLQRVKLLLMLVTALTI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHH
GVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVGVGMIAVTGGLTFSAFYDTPAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
PSVVLCAALLFIFSMMKKQAS
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAV
CCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IAVTLLLAAGLVWLEKRPHLAIDTLLGIMAHSALSLGLVVVSLMSNVRVDLMAYLFGDLL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFVDGVKLQRVKLLLMLVTALTI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHH
GVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVGVGMIAVTGGLTFSAFYDTPAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
PSVVLCAALLFIFSMMKKQAS
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 2842314; 7984428; 9680209 [H]