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The map label for this gene is uspC

Identifier: 194737101

GI number: 194737101

Start: 2000741

End: 2001169

Strand: Direct

Name: uspC

Synonym: SeSA_A2082

Alternate gene names: 194737101

Gene position: 2000741-2001169 (Clockwise)

Preceding gene: 194736100

Following gene: 194735490

Centisome position: 42.49

GC content: 52.21

Gene sequence:

>429_bases
ATGAGCTACACCCATATTCTTGTCGCCGTTGCCGTCACCCCGGAAAGTCACCAGCTACTGGCTAAAGCGGTCTCTATCGC
CCGCCCTGTTCAGGCGAAAGTAAGCCTGATTACTCTCGCTTCCGATCCCGAACTGTATAACCAGTTCGCCGCGCCCATGA
TGGAGGATTTACGCGCGGTTATGCATGAGGAAACTGAGAATTTTCTTAAGATGCTGGGGGAAAAGGCGGATTATCCGATT
GAACAAACTTTCATCGCATCAGGTGAGTTAAGCCAGCATATTTTGGCTGTGTGCCGCAAACACCATGTTGATCTGGTCAT
TTGCGGCAACCATAACCACAGTTTCTTTTCGCGCGCGTCCTGCTCGGCAAAAAGTGTCGTCAGCGCCAGCCAGGTAGATG
TGTTGCTGGTGCCGTTAGCGGGCGACTAG

Upstream 100 bases:

>100_bases
ATGTCCTTCACATTAATGTGGCATTAGCGCATTGCAGAAATGCGCTAAACAGAGTAAAGCTAAAGCACAATCTCATATTC
TTGCAATCAAGGAGCGAGTT

Downstream 100 bases:

>100_bases
TCGCCGCTCGCAATATTTCAGGCCAGCTTAGGGAACGTCGCCACGTTGTTCTGCTGCTGACGCTCAGGGCTACGCGGCGT
GACCTCCTTTAGGTCATGAA

Product: universal stress protein UspC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPELYNQFAAPMMEDLRAVMHEETENFLKMLGEKADYPI
EQTFIASGELSQHILAVCRKHHVDLVICGNHNHSFFSRASCSAKSVVSASQVDVLLVPLAGD

Sequences:

>Translated_142_residues
MSYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPELYNQFAAPMMEDLRAVMHEETENFLKMLGEKADYPI
EQTFIASGELSQHILAVCRKHHVDLVICGNHNHSFFSRASCSAKSVVSASQVDVLLVPLAGD
>Mature_141_residues
SYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPELYNQFAAPMMEDLRAVMHEETENFLKMLGEKADYPIE
QTFIASGELSQHILAVCRKHHVDLVICGNHNHSFFSRASCSAKSVVSASQVDVLLVPLAGD

Specific function: Required for resistance to DNA-damaging agents

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

Organism=Escherichia coli, GI1788205, Length=142, Percent_Identity=76.7605633802817, Blast_Score=232, Evalue=9e-63,
Organism=Escherichia coli, GI1789909, Length=140, Percent_Identity=41.4285714285714, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790358, Length=140, Percent_Identity=30.7142857142857, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): USPC_SALTY (Q9RM66)

Other databases:

- EMBL:   D43640
- EMBL:   AE006468
- RefSeq:   NP_460884.1
- ProteinModelPortal:   Q9RM66
- SMR:   Q9RM66
- PRIDE:   Q9RM66
- GeneID:   1253448
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1927
- HOGENOM:   HBG733992
- OMA:   SIARPVN
- ProtClustDB:   PRK10116
- BioCyc:   STYP99287:STM1927-MONOMER
- GO:   GO:0005737
- InterPro:   IPR014729
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 15498; Mature: 15367

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPELYNQFAAPMMEDLRAV
CCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
MHEETENFLKMLGEKADYPIEQTFIASGELSQHILAVCRKHHVDLVICGNHNHSFFSRAS
HHHHHHHHHHHHCCCCCCCHHHEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHCC
CSAKSVVSASQVDVLLVPLAGD
CCHHHHCCCCCCCEEEEEECCC
>Mature Secondary Structure 
SYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPELYNQFAAPMMEDLRAV
CCEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
MHEETENFLKMLGEKADYPIEQTFIASGELSQHILAVCRKHHVDLVICGNHNHSFFSRAS
HHHHHHHHHHHHCCCCCCCHHHEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHCC
CSAKSVVSASQVDVLLVPLAGD
CCHHHHCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10586519; 11677609