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The map label for this gene is hemA [H]

Identifier: 194737032

GI number: 194737032

Start: 1850479

End: 1851735

Strand: Reverse

Name: hemA [H]

Synonym: SeSA_A1914

Alternate gene names: 194737032

Gene position: 1851735-1850479 (Counterclockwise)

Preceding gene: 194736262

Following gene: 194736546

Centisome position: 39.32

GC content: 56.8

Gene sequence:

>1257_bases
ATGACCCTTTTAGCGCTCGGTATTAACCATAAAACGGCACCTGTATCGCTGCGAGAACGCGTAACGTTTTCGCCGGACAC
GCTTGATCAGGCGCTGGACAGCCTGCTTGCGCAGCCAATGGTGCAGGGCGGGGTCGTGCTGTCAACCTGTAACCGTACAG
AACTGTATTTGAGCGTGGAAGAGCAGGATAACCTGCAGGAAGCGCTGATCCGCTGGTTATGCGATTACCATAACCTGAAC
GAGGACGATCTGCGCAACAGTCTGTACTGGCATCAGGACAATGACGCCGTCAGCCACCTGATGCGCGTCGCCAGCGGTCT
GGATTCACTGGTGCTGGGCGAACCGCAAATCCTCGGTCAGGTGAAAAAAGCGTTTGCGGATTCGCAAAAAGGCCACCTTA
ACGCCAGCGCGCTGGAGCGAATGTTTCAGAAGTCGTTTTCCGTCGCCAAGCGAGTGCGGACTGAAACCGATATCGGCGCC
AGCGCCGTCTCCGTCGCGTTTGCCGCCTGTACGCTCGCTCGCCAAATCTTTGAATCGCTCTCGACGGTCACTGTACTGTT
AGTTGGCGCGGGCGAAACTATTGAACTAGTGGCGCGTCACCTGCGCGAGCATAAAGTACAAAAGATGATTATCGCCAACC
GAACCCGCGAGCGCGCGCAAGCCCTGGCGGATGAAGTAGGCGCTGAGGTTATCTCGCTCAGCGATATCGACGCCCGTTTG
CAGGATGCCGATATTATCATCAGTTCGACCGCCAGCCCGCTGCCGATTATCGGTAAAGGCATGGTGGAGCGCGCATTAAA
AAGCCGTCGCAACCAGCCGATGCTGCTGGTGGATATCGCCGTACCGCGCGACGTTGAGCCGGAAGTCGGCAAACTGGCGA
ACGCTTATCTTTATAGCGTCGATGATTTACAGAGCATCATTTCGCATAATCTGGCGCAGCGTCAGGCTGCGGCGGTAGAA
GCGGAAACGATTGTTGAGCAGGAAGCCAGCGAGTTTATGGCCTGGCTACGCGCCCAGGGGGCCAGCGAGACCATTCGGGA
ATACCGTAGTCAGTCGGAGCAGATTCGTGACGAACTGACTACCAAAGCGCTGTCGGCCCTTCAACAGGGCGGTGATGCGC
AAGCCATCTTGCAGGATCTGGCATGGAAACTGACCAACCGCCTGATTCATGCGCCAACGAAATCACTTCAACAGGCTGCC
CGTGACGGGGATGACGAACGCCTGAATATTCTGCGCGACAGCCTCGGGCTGGAGTAG

Upstream 100 bases:

>100_bases
CCAATTACTCCAAAAGGGGGCTCTCTCTTTTATTGACCACGCGCATCCTGTATGATGCAAGCAGACTAACCATATCAACG
CTGGTACTACTCCCGCAGAC

Downstream 100 bases:

>100_bases
CAGCACACACCACACTTTTTTACAGGGTGAATTTACGCCTATGAAGCCTTCTATCGTTGCCAAACTGGAAGCCCTGCACG
AACGCCATGAGGAAGTTCAG

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLN
EDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGA
SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARL
QDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVE
AETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAA
RDGDDERLNILRDSLGLE

Sequences:

>Translated_418_residues
MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLN
EDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGA
SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARL
QDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVE
AETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAA
RDGDDERLNILRDSLGLE
>Mature_417_residues
TLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNE
DDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGAS
AVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARLQ
DADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEA
ETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAAR
DGDDERLNILRDSLGLE

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=418, Percent_Identity=94.4976076555024, Blast_Score=788, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR003462
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 46106; Mature: 45975

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVE
CEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEEC
EQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQ
CCCCHHHHHHHHHHHHCCCCHHHHHCCCCEECCCHHHHHHHHHHHCCHHHHCCCHHHHHH
VKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
STVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARL
HHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHH
QDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
CCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
DDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVE
EEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEEC
EQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQ
CCCCHHHHHHHHHHHHCCCCHHHHHCCCCEECCCHHHHHHHHHHHCCHHHHCCCHHHHHH
VKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
STVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARL
HHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHH
QDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
CCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
DDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA