Click here to switch to the map view.

The map label for this gene is ycbL [C]

Identifier: 194736864

GI number: 194736864

Start: 3814572

End: 3815453

Strand: Direct

Name: ycbL [C]

Synonym: SeSA_A3944

Alternate gene names: 194736864

Gene position: 3814572-3815453 (Clockwise)

Preceding gene: 194735379

Following gene: 194738366

Centisome position: 81.0

GC content: 51.59

Gene sequence:

>882_bases
ATGAATCGCTATGCATTATTCTTTGTATGTATATTTTCAACATCAGCACTTCCTGCCATGGCGGCATTAGATCCTTCACA
ACCGTTATCACCCGCGCCTCCGTTATCACTGTTTAAAGCGTGGGCTAAGCCTATGAAGCCGTTTCAAATCACAGAAGGCG
TGTGGTATGTCGGCACGGAAAATCTCTCTTCTATTCTGCTGACCACCCCGGCAGGGCATATTCTTATTGATGCGGGATTG
GATGAAAGCGCACCGCAAATTAAAGCGAATATTGAAGCGGCAGGATTCCGCCTCACAGACATACGCTATCTATTGAACAG
CCATGCGCGGCTGGATCAAGCGGGGGGCATGGCACGTTTGAAAGCGTGGAGCGGCGCACAATTGGTCGCCAGCCAACCCA
ACGCCGATCAGATGGCGAGGGGTGGACGAGAGGATTTTGCGCTTGGCGATGCGCTCCCCTTCCCGCCCGTCACCACTGAT
AAAATTATCCACAACCAGGAAAGCATCAGCCTCGGAGGGATAACCGTGACAGCACTATTCACGCCCGGACATCTGCCCGG
CTCAACTTCCTGGCGCGTAACGCTCCGCAACGGCAAGACGCTAATTTACGCAGATAGTCTCGCCACGCCCGACTATCTGC
TGATTAACAACAAAAACTACCCTGACCTGGTTACTGATATTCAGAGTAGCTTTAAGACACTGGCCGCCCAGCATGTTGAT
ATCTTTATTGCCAACAAAGGTGACCGCTTCGGGCTACTGGAGAAACGACAGCAACTTCGCAACGGCGATACACAGGCATT
CTTTGATTCCAATGGCTTGCAACAGTATGTGGAACGCTCACGTCAGCGCTTCATCACACAACTTACCGCACAGCAGCCAT
AA

Upstream 100 bases:

>100_bases
GTTCATATCCATTTGCAGCAAGTTCATTAAACGTCTCTCTTATTGAACCTGGCTAAATTACTGCCAGGTATACTGCGGGC
GCTTCAATCAGGAGAACATT

Downstream 100 bases:

>100_bases
TGAAATGACGCACCGGCGGCGCGTCCAGGGCGCCGTTCAGGTAATTTATCTAAGTCAAAACAGAAAAACCTCGCATACAA
TAAACCACAAAAATGACGTT

Product: beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase type II; Penicillinase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNRYALFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPMKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGL
DESAPQIKANIEAAGFRLTDIRYLLNSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGREDFALGDALPFPPVTTD
KIIHNQESISLGGITVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP

Sequences:

>Translated_293_residues
MNRYALFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPMKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGL
DESAPQIKANIEAAGFRLTDIRYLLNSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGREDFALGDALPFPPVTTD
KIIHNQESISLGGITVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP
>Mature_293_residues
MNRYALFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPMKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGL
DESAPQIKANIEAAGFRLTDIRYLLNSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGREDFALGDALPFPPVTTD
KIIHNQESISLGGITVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP

Specific function: Has a high activity against imipenem [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32118; Mature: 32118

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYALFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPMKPFQITEGVWYVGTE
CCCEEEEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCEEEEECC
NLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRLTDIRYLLNSHARLDQAGGMARL
CCCEEEEECCCCEEEEECCCCCCCCCEEEEEECCCEEHHHHHHHHHCCCHHHHCCCEEEE
KAWSGAQLVASQPNADQMARGGREDFALGDALPFPPVTTDKIIHNQESISLGGITVTALF
EECCCCEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCEEEEEEE
TPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
ECCCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEE
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP
EEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRYALFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPMKPFQITEGVWYVGTE
CCCEEEEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCEEEEECC
NLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRLTDIRYLLNSHARLDQAGGMARL
CCCEEEEECCCCEEEEECCCCCCCCCEEEEEECCCEEHHHHHHHHHCCCHHHHCCCEEEE
KAWSGAQLVASQPNADQMARGGREDFALGDALPFPPVTTDKIIHNQESISLGGITVTALF
EECCCCEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCEEEEEEE
TPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
ECCCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEE
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP
EEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8018721; 3931629; 9811546 [H]