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The map label for this gene is sdaA [H]

Identifier: 194736507

GI number: 194736507

Start: 1901388

End: 1902752

Strand: Direct

Name: sdaA [H]

Synonym: SeSA_A1970

Alternate gene names: 194736507

Gene position: 1901388-1902752 (Clockwise)

Preceding gene: 194737033

Following gene: 194737036

Centisome position: 40.38

GC content: 55.24

Gene sequence:

>1365_bases
GTGATTAGCCTATTCGACATGTTTAAGGTAGGGATTGGCCCCTCCTCTTCCCACACTGTTGGCCCGATGAAGGCCGGTAA
ACAGTTCGTCGATGACCTGGTCGAAAAAGGATTACTGGATAACGTTACCCGCGTCGCTGTCGATGTCTACGGCTCGCTGT
CGCTGACGGGGAAAGGTCACCATACCGATATCGCCATTATTATGGGTCTGGCGGGTAATGAACCCGCTACCGTGGATATT
GATAGTATCCCCGGTTTTATTCGCGACGTCGAAACGCGCGGGCGTCTGTTACTGGCCCAGGGACGTCACGAAGTCGACTT
CCCGAAAGATGACGGAATGCGTTTTCACAACGGCAATTTGCCGCTGCATGAAAACGGGATGCAGATCCACGCCTGGCATA
ACGACACGGTCATTTATAGCAAGACGTACTATTCCATCGGCGGCGGCTTTATCGTTGATGAAGCGCATTTCGGCCAGGAA
GCGACGAATGAGGTTACTGTACCTTATCCGTTTAAATCGGCGAAAGAAATGCTGGAGTATTGCAACAGCACCGGCCTTTC
ACTCTCCGGCATGGTGATGCAAAACGAACTGGCGCTACATAGCAAGAAAGAGATTGAAGAGTATTTCGGTCACGTCTGGC
AGACCATGCAGGCCTGTATTGATCGCGGTATGAATACCGAAGGCGTTCTGCCGGGGCCGCTGCGCGTACCGCGTCGCGCC
TCTGCGCTGCGTCGTATGCTGGTTTCCAGCGATAAGCTTTCCAACGATCCGATGAACGTCATTGACTGGGTGAACATGTT
TGCTCTGGCGGTGAACGAAGAGAACGCCGCAGGCGGTCGCGTCGTGACGGCGCCAACCAACGGCGCATGCGGCATCGTTC
CTGCGGTACTGGCTTACTACGACCATTTTATTGAGTCTGTCAGCCCGGATATTTACACCCGCTACTTCCTGGCGGCAGGC
GCTATTGGCGCGCTGTATAAGATGAACGCGTCTATTTCCGGCGCGGAAGTCGGCTGTCAGGGTGAAGTCGGGGTCGCCTG
TTCGATGGCGGCGGCAGGCCTTGCTGAACTGTTGGGCGCCAGCCCGGAACAGGTTTGCGTTGCCGCTGAAATCGGCATGG
AGCATAACCTGGGGCTGACCTGCGACCCGGTTGCCGGTCAGGTGCAGGTACCGTGTATCGAGCGTAACGCCATTGCTTCA
GTTAAAGCGATCAATGCTGCGCGTATGGCTATGCGTCGAACCAGCGCGCCGCGCGTCTCGCTGGATAAAGTCATCGAAAC
GATGTACGAGACCGGAAAAGACATGAACGCAAAATACCGCGAAACATCGCGCGGCGGGTTGGCCATTAAAGTCCAGTGTG
ATTAA

Upstream 100 bases:

>100_bases
TCATGTGAATAGTTAAGCTGATGCCAGCGTTCCCTCTTACACTATGCGCAGTTATAACATCGTAACCGGAAGCCCCGGTT
GCCCTGTCAGGAGTATTATC

Downstream 100 bases:

>100_bases
ACGCCGTTTCCCCTCCCTTCGCCCATCTGCTACGGATGGGCGAAATTTTTATCTCTTCCTCGTCGACTCCACGTTTCCCC
ACTACACTTGCTGTGTCGCG

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH 1; L-serine deaminase 1; L-SD1 [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDI
DSIPGFIRDVETRGRLLLAQGRHEVDFPKDDGMRFHNGNLPLHENGMQIHAWHNDTVIYSKTYYSIGGGFIVDEAHFGQE
ATNEVTVPYPFKSAKEMLEYCNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQACIDRGMNTEGVLPGPLRVPRRA
SALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFLAAG
AIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINAARMAMRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD

Sequences:

>Translated_454_residues
MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDI
DSIPGFIRDVETRGRLLLAQGRHEVDFPKDDGMRFHNGNLPLHENGMQIHAWHNDTVIYSKTYYSIGGGFIVDEAHFGQE
ATNEVTVPYPFKSAKEMLEYCNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQACIDRGMNTEGVLPGPLRVPRRA
SALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFLAAG
AIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINAARMAMRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD
>Mature_454_residues
MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDI
DSIPGFIRDVETRGRLLLAQGRHEVDFPKDDGMRFHNGNLPLHENGMQIHAWHNDTVIYSKTYYSIGGGFIVDEAHFGQE
ATNEVTVPYPFKSAKEMLEYCNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQACIDRGMNTEGVLPGPLRVPRRA
SALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFLAAG
AIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINAARMAMRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=454, Percent_Identity=94.273127753304, Blast_Score=895, Evalue=0.0,
Organism=Escherichia coli, GI1789161, Length=455, Percent_Identity=76.9230769230769, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=453, Percent_Identity=73.0684326710817, Blast_Score=676, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48968; Mature: 48968

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTRVAVDVYGSLSLTGKGH
CCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
HTDIAIIMGLAGNEPATVDIDSIPGFIRDVETRGRLLLAQGRHEVDFPKDDGMRFHNGNL
CCEEEEEEEECCCCCCEEEHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEECCCC
PLHENGMQIHAWHNDTVIYSKTYYSIGGGFIVDEAHFGQEATNEVTVPYPFKSAKEMLEY
CEECCCCEEEEEECCEEEEEEEEEECCCCEEEECHHCCCCCCCCEECCCCCHHHHHHHHH
CNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQACIDRGMNTEGVLPGPLRVPRRA
HCCCCCEEECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
SALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DHFIESVSPDIYTRYFLAAGAIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGA
HHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIASVKAINAARMAMRRTSAPRVS
CHHHEEEEEECCCCCCCCEEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHHCCCCCCC
LDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD
HHHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEEC
>Mature Secondary Structure
MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTRVAVDVYGSLSLTGKGH
CCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
HTDIAIIMGLAGNEPATVDIDSIPGFIRDVETRGRLLLAQGRHEVDFPKDDGMRFHNGNL
CCEEEEEEEECCCCCCEEEHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEECCCC
PLHENGMQIHAWHNDTVIYSKTYYSIGGGFIVDEAHFGQEATNEVTVPYPFKSAKEMLEY
CEECCCCEEEEEECCEEEEEEEEEECCCCEEEECHHCCCCCCCCEECCCCCHHHHHHHHH
CNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQACIDRGMNTEGVLPGPLRVPRRA
HCCCCCEEECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
SALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DHFIESVSPDIYTRYFLAAGAIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGA
HHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIASVKAINAARMAMRRTSAPRVS
CHHHEEEEEECCCCCCCCEEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHHCCCCCCC
LDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD
HHHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2504697; 8436113; 9097040; 9278503 [H]