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The map label for this gene is ipk [H]

Identifier: 194736140

GI number: 194736140

Start: 1852672

End: 1853520

Strand: Direct

Name: ipk [H]

Synonym: SeSA_A1917

Alternate gene names: 194736140

Gene position: 1852672-1853520 (Clockwise)

Preceding gene: 194736828

Following gene: 194735902

Centisome position: 39.34

GC content: 54.89

Gene sequence:

>849_bases
ATGACCCATTGGCCTTCTCCGGCAAAATTAAATCTGTTTTTATATATCACCGGACAGCGAGCAGACGGCTACCACACGCT
GCAGACGCTGTTTCAGTTTCTGGATTATGGCGACACACTCCACATCGAACCGCGTCACGATGGCGAAATCCATTTATTAA
CGCCGGTTACCGGCGTTGAAAATGAAGACAATCTGATCGTCCGCGCCGCGCGGCTGTTGATGAAAGCCGCCTCGGAGAGT
GGACGCCTGCCCGTCGGAAGCGGTGCGGATATCAGCATTGAGAAGCGCCTTCCCATGGGCGGCGGTCTGGGCGGCGGCTC
GTCTAACGCCGCGACCGTTCTGGTGGCGCTCAATCATCTTTGGCAATGCGGGCTTTCCATTGATGAACTGGCGACGCTCG
GCCTGACGCTCGGCGCCGACGTCCCGGTCTTTGTTCGTGGCCACGCCGCGTTTGCCGAAGGCGTAGGCGAAATATTAACG
CCGGTGAATCCGCCGGAAAAATGGTATCTGGTCGCGCACCCTGGCGTAAGCATTCCGACGCCGGTTATCTTTAAAGATCC
TCAATTGCCGCGTAATACGCCAAAAAGGTCAATAGATACGTTACTAAAATGTGAATTCAGCAATGATTGCGAGGTTATCG
CAAGAAAACGTTTTCGCGAGGTTGATGCGGCGCTTTCCTGGCTGTTAGAATACGCGCCGTCGCGCCTGACTGGGACAGGG
GCCTGTGTCTTTGCTGAATTCGATACAGAGTCTTGTGCTCGCCAGGTGCTTGAGCAAGCCCCGGAATGGCTCAATGCTTT
TGTGGCGAAGGGTGTCAACCTCTCCCCATTGCATCGAGAGTTACTCTAA

Upstream 100 bases:

>100_bases
GCTATGACAGCAAAACGCAGCCTGCCATGCCTGCCAATATGGAGCTTTCAGACGGCAGTCAGCGCATTAAGCTGAAAATG
GATAACTGGATTGTGAAATG

Downstream 100 bases:

>100_bases
CGCATTCGGGTTTCAGGAAGATGGCGAAATGACGAGTCGCCGGTCATATATGCCGTATTTGACCGGTGTGAGGCATTGAT
ACCAGCGCACATGAAACGTG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGVENEDNLIVRAARLLMKAASES
GRLPVGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILT
PVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTG
ACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL

Sequences:

>Translated_282_residues
MTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGVENEDNLIVRAARLLMKAASES
GRLPVGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILT
PVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTG
ACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
>Mature_281_residues
THWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGVENEDNLIVRAARLLMKAASESG
RLPVGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTP
VNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTGA
CVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=281, Percent_Identity=90.3914590747331, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30740; Mature: 30608

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGVE
CCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCC
NEDNLIVRAARLLMKAASESGRLPVGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
WQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIPT
HHCCCCHHHHHHHHEHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
PVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTG
CEEEECCCCCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
>Mature Secondary Structure 
THWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGVE
CCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCC
NEDNLIVRAARLLMKAASESGRLPVGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
WQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIPT
HHCCCCHHHHHHHHEHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
PVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTG
CEEEECCCCCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA