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The map label for this gene is gmuD [H]

Identifier: 194736129

GI number: 194736129

Start: 3856430

End: 3857812

Strand: Direct

Name: gmuD [H]

Synonym: SeSA_A3983

Alternate gene names: 194736129

Gene position: 3856430-3857812 (Clockwise)

Preceding gene: 194735474

Following gene: 194736257

Centisome position: 81.89

GC content: 53.43

Gene sequence:

>1383_bases
ATGCGATACCGTTTTCCCGATAACTTCTGGTGGGGCAGCGCCTGCTCAGCGTTGCAAACCGAAGGGGATAGTCTGAATGG
CGGTAAAAGCCAGACCACGTGGGATGTGTGGTTCGAGCGCCAGCCGGGTCGTTTTCATCAGGGCATCGGTCCAGCAGAAA
CCTCAACGTTCTATCGCCACTGGAAGCAAGACATCGCGCTACTGAAACAGTTAAAACATAACAGTTTTCGCACCTCGCTA
AGCTGGGCGCGGCTCATTCCAGACGGCGTAGGCGAGGTGAATCCACAAGCGGTGAGCTTCTACAATCACGTCATCGACGA
GCTACTGGCGCAGGGCATCACGCCGTTTATTACGCTGTTCCATTTTGATATGCCGATGGTCATGCAGGAGAAAGGCGGCT
GGGAAAATCGCGACGTCGTAGAGGCGTTTGGTCGGTACGCGCAAACGTGTTTTACCTTGTTTGGCGACCGCGTGAAGCAC
TGGTTTACCTTTAACGAGCCGATTGTGCCGGTGGAAGGCGGCTATTTGTACGACTTCCACTATCCCAATGTGGTGGATTT
TAAACGTGCAGCCACCGTGGCGTACCATACCGTGCTGGCGCACTCGACCGCCGTGCGCGCCTGGCGCGCCGGGCGCTACG
ACGGTGAAATCGGCGTAGTGCTGAATCTGACGCCGTCCTACCCACGCTCGCAGCATCCCGCCGATGTACAAGCCGCGCAT
CATGCGGATCTGTTATTCAACCGCAGTTTTCTTGACCCGGTATTAAAGGGAGAATACCCGGCGGACTTGGTGGCGCTGCT
GAAAACCTATGACCAGTTGCCTGCCTGTCAGCCAGGCGATCGTCAGCTTATTACCGACGGCAAAATCGATTTACTGGGGA
TTAACTATTATCAGCCGCGCCGCGTGAAATGCCGTGATACGGCGGTGAATCCGCAAGCGCCGTTTATGCCGGAGTGGTTA
TTTGACTATTACGACATGCCGGGGCGCAAGATGAACCCTTACCGCGGCTGGGAAATTTACGCGCCAGGAATTTACGACAT
CATCACCAACCTGCGGGATAATTACGGCAATCCGCGCTGTTTTATCTCCGAAAACGGGATAGGCGTTGAGAACGAGCAGC
GTTTTGTGCAAGCGGGACAGATTCACGATGATTACCGGATTGACTTTATTTCTGAGCATCTTAAATGGCTGCATAAAGGC
ATTAGCGAGGGCTGTCACTGTCTTGGCTACCACATGTGGACCTTTATCGATAACTGGTCATGGCTGAACGGCTATAAAAA
TCGCTATGGTTTTGTACAACTGGATTTAGCCACCCAAACGCGCACGGTGAAAAAAAGCGGAGAATGGTTTGCCGCCACCG
CAGAGCATAACGGTTTTGATTAA

Upstream 100 bases:

>100_bases
CTTTTCCGTTTTTTGGTCGCGAAAATGCGGACTGTAACCGGTTTCTGTTCGCCAAAATCGCGTATTCTGGAGCGAATTTA
CGCGATCAAGGAGTACGACA

Downstream 100 bases:

>100_bases
GCGTTTATTATTGCCGGATGACGACTAACGTCGTATCCGGCCTACAAATGGCAGCAATATCAACTCATTGGCGTAATACG
GACTTTCGCCGCCACGACTA

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPGRFHQGIGPAETSTFYRHWKQDIALLKQLKHNSFRTSL
SWARLIPDGVGEVNPQAVSFYNHVIDELLAQGITPFITLFHFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKH
WFTFNEPIVPVEGGYLYDFHYPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIGVVLNLTPSYPRSQHPADVQAAH
HADLLFNRSFLDPVLKGEYPADLVALLKTYDQLPACQPGDRQLITDGKIDLLGINYYQPRRVKCRDTAVNPQAPFMPEWL
FDYYDMPGRKMNPYRGWEIYAPGIYDIITNLRDNYGNPRCFISENGIGVENEQRFVQAGQIHDDYRIDFISEHLKWLHKG
ISEGCHCLGYHMWTFIDNWSWLNGYKNRYGFVQLDLATQTRTVKKSGEWFAATAEHNGFD

Sequences:

>Translated_460_residues
MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPGRFHQGIGPAETSTFYRHWKQDIALLKQLKHNSFRTSL
SWARLIPDGVGEVNPQAVSFYNHVIDELLAQGITPFITLFHFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKH
WFTFNEPIVPVEGGYLYDFHYPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIGVVLNLTPSYPRSQHPADVQAAH
HADLLFNRSFLDPVLKGEYPADLVALLKTYDQLPACQPGDRQLITDGKIDLLGINYYQPRRVKCRDTAVNPQAPFMPEWL
FDYYDMPGRKMNPYRGWEIYAPGIYDIITNLRDNYGNPRCFISENGIGVENEQRFVQAGQIHDDYRIDFISEHLKWLHKG
ISEGCHCLGYHMWTFIDNWSWLNGYKNRYGFVQLDLATQTRTVKKSGEWFAATAEHNGFD
>Mature_460_residues
MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPGRFHQGIGPAETSTFYRHWKQDIALLKQLKHNSFRTSL
SWARLIPDGVGEVNPQAVSFYNHVIDELLAQGITPFITLFHFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKH
WFTFNEPIVPVEGGYLYDFHYPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIGVVLNLTPSYPRSQHPADVQAAH
HADLLFNRSFLDPVLKGEYPADLVALLKTYDQLPACQPGDRQLITDGKIDLLGINYYQPRRVKCRDTAVNPQAPFMPEWL
FDYYDMPGRKMNPYRGWEIYAPGIYDIITNLRDNYGNPRCFISENGIGVENEQRFVQAGQIHDDYRIDFISEHLKWLHKG
ISEGCHCLGYHMWTFIDNWSWLNGYKNRYGFVQLDLATQTRTVKKSGEWFAATAEHNGFD

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=491, Percent_Identity=30.5498981670061, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI13273313, Length=484, Percent_Identity=28.9256198347107, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI32481206, Length=489, Percent_Identity=31.2883435582822, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI28376633, Length=466, Percent_Identity=25.1072961373391, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI24497614, Length=480, Percent_Identity=25.625, Blast_Score=136, Evalue=4e-32,
Organism=Escherichia coli, GI1789070, Length=490, Percent_Identity=33.469387755102, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI2367174, Length=494, Percent_Identity=30.9716599190283, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=30.0420168067227, Blast_Score=181, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17539390, Length=470, Percent_Identity=32.1276595744681, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17552856, Length=470, Percent_Identity=30.8510638297872, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI21356577, Length=481, Percent_Identity=27.4428274428274, Blast_Score=196, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53185; Mature: 53185

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPGRFHQGIGPAETSTFYRH
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHH
WKQDIALLKQLKHNSFRTSLSWARLIPDGVGEVNPQAVSFYNHVIDELLAQGITPFITLF
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
HFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKHWFTFNEPIVPVEGGYLYDFH
HCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCEEEEEC
YPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIGVVLNLTPSYPRSQHPADVQAAH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
HADLLFNRSFLDPVLKGEYPADLVALLKTYDQLPACQPGDRQLITDGKIDLLGINYYQPR
HHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCCC
RVKCRDTAVNPQAPFMPEWLFDYYDMPGRKMNPYRGWEIYAPGIYDIITNLRDNYGNPRC
CCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCEE
FISENGIGVENEQRFVQAGQIHDDYRIDFISEHLKWLHKGISEGCHCLGYHMWTFIDNWS
EEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WLNGYKNRYGFVQLDLATQTRTVKKSGEWFAATAEHNGFD
HHCCCCCCCCEEEEEECCHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPGRFHQGIGPAETSTFYRH
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHH
WKQDIALLKQLKHNSFRTSLSWARLIPDGVGEVNPQAVSFYNHVIDELLAQGITPFITLF
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
HFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKHWFTFNEPIVPVEGGYLYDFH
HCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCEEEEEC
YPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIGVVLNLTPSYPRSQHPADVQAAH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
HADLLFNRSFLDPVLKGEYPADLVALLKTYDQLPACQPGDRQLITDGKIDLLGINYYQPR
HHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCCC
RVKCRDTAVNPQAPFMPEWLFDYYDMPGRKMNPYRGWEIYAPGIYDIITNLRDNYGNPRC
CCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCEE
FISENGIGVENEQRFVQAGQIHDDYRIDFISEHLKWLHKGISEGCHCLGYHMWTFIDNWS
EEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WLNGYKNRYGFVQLDLATQTRTVKKSGEWFAATAEHNGFD
HHCCCCCCCCEEEEEECCHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]