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The map label for this gene is pbpG [H]

Identifier: 194736053

GI number: 194736053

Start: 2285992

End: 2286900

Strand: Reverse

Name: pbpG [H]

Synonym: SeSA_A2406

Alternate gene names: 194736053

Gene position: 2286900-2285992 (Counterclockwise)

Preceding gene: 194735564

Following gene: 194736410

Centisome position: 48.56

GC content: 54.46

Gene sequence:

>909_bases
ATGTTGGCCGTACCTTTTGCCCCGCAGGCCGTGGCGAAAACGGCAGCGACAACCGCGGCGTCTCAACCTGAGATTGCCTC
CGGTAGCGCAATGATTGTTGATCTCAACACCAATAAAGTGATCTATTCGAACCACCCGGATCTGGTGCGTCCGATTGCCT
CAATAACCAAATTAATGACGGCGATGGTCGTGCTCGACGCGCGATTGCCGCTGGATGAAATACTGAAGGTCGATATCAGC
CAGACGCCGGAAATGAAAGGGGTTTACTCCCGCGTGCGCCTGAACAGCGAAATTAGTCGCAAAAATATGTTGCTGCTGGC
GTTGATGTCATCCGAAAACCGTGCGGCGGCAAGCCTGGCGCACTATTATCCTGGCGGTTATAACGCGTTTATTAAAGCGA
TGAATGCGAAGGCGAAAGCGCTGGGCATGACGCATACCCGCTTCGTTGAGCCGACGGGGCTGTCGATTCATAACGTCTCG
ACCGCGCGGGATTTAACAAAACTGCTGATTGCCACGAAGCAATACCCGCTGATTGGCCAGCTAAGCACCACGCGCGAAGA
CATGGCGACATTCTCGCATCCGGCGTATACGCTGCCGTTTCGCAATACCAACCATTTGGTCTACCGTGATAACTGGAATA
TCCAGTTAACGAAAACCGGCTTTACCAATGCGGCGGGGCATTGCCTGGTGATGCGTACCGTGATCAATAACAAACCGGTC
GCGCTGGTGGTCATGGATGCGTTCGGCAAATATACCCACTTTGCGGACGCCAGTCGCCTGCGTACATGGATTGAAACCGG
TAAAGTCATGCCCGTTCCGGCTGCCGCGCTGAGCTATAAAAAGCAAAAAGCCGCGCAAATGGCGGCAGCCAGCGCCAGCG
CCGGAGCGCAAACCGCACAGAACGATTAA

Upstream 100 bases:

>100_bases
ATAATCTTAGCTCAGGCGGTGTGCGTTACGACGCGCGTGAATCATTATCAGAAATCTCATCATGCTGAAATTCCGAGCTT
CATTCCTGAGCCTTGCTCTG

Downstream 100 bases:

>100_bases
GTCGCCGCAGGCCCGGCAGGCATCGCGCCGCCGGGCATTCACGGTAAACCGCACGGTGTTAATGCGTTTCGTCGGGCGTA
TTTTCCTGCCAGAATTTCCG

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMTAMVVLDARLPLDEILKVDIS
QTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVS
TARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPV
ALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQND

Sequences:

>Translated_302_residues
MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMTAMVVLDARLPLDEILKVDIS
QTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVS
TARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPV
ALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQND
>Mature_302_residues
MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMTAMVVLDARLPLDEILKVDIS
QTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVS
TARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPV
ALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQND

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=279, Percent_Identity=94.9820788530466, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1787062, Length=271, Percent_Identity=29.1512915129151, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082022, Length=275, Percent_Identity=26.9090909090909, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786851, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 32809; Mature: 32809

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMT
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHH
AMVVLDARLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLA
HHHHHHCCCCHHHHHEECCCCCCCHHHHHHHHHCCCHHCCCCEEEEEEECCCCHHHHHHH
HYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQ
HHCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCEEECCHHHHHHHHHHHHHCCCCCEEC
LSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPV
CCCCHHHHHHHCCCCEEECCCCCCEEEEECCCEEEEEECCCCCCCCCEEEEEEHHCCCCE
ALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQ
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
ND
CC
>Mature Secondary Structure
MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMT
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHH
AMVVLDARLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLA
HHHHHHCCCCHHHHHEECCCCCCCHHHHHHHHHCCCHHCCCCEEEEEEECCCCHHHHHHH
HYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQ
HHCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCEEECCHHHHHHHHHHHHHCCCCCEEC
LSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPV
CCCCHHHHHHHCCCCEEECCCCCCEEEEECCCEEEEEECCCCCCCCCEEEEEEHHCCCCE
ALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQ
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
ND
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]