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The map label for this gene is sapC [H]

Identifier: 194735977

GI number: 194735977

Start: 1763663

End: 1764553

Strand: Direct

Name: sapC [H]

Synonym: SeSA_A1823

Alternate gene names: 194735977

Gene position: 1763663-1764553 (Clockwise)

Preceding gene: 194735684

Following gene: 194735415

Centisome position: 37.45

GC content: 57.58

Gene sequence:

>891_bases
ATGCCTTACGATAGCGTCTACAGCGAAAAGCGCCCGCCAGGCACCCTGCGTACTGCCTGGCGCAAATTTTATAGCGACGC
GCCTGCGATGGTGGGTCTGTATGGATGCGCCGGTCTGGCGTTGTTGTGTATTTTTGGCGGCTGGATCGCGCCCTATGGTA
TCGATCAGCAATTTTTGGGCTATCAGCTACTGCCGCCCTCCTGGTCACGCTATGGCGAAGTCTCCTTTTTTCTGGGGACT
GACGATCTGGGGCGCGATGTGCTGAGCCGCCTGTTAAGCGGCGCGGCGCCCACGGTCGGCGGCGCGTTTATCGTAACGCT
GGCGGCTACGCTATGTGGATTAGTCCTCGGCGTAGTGGCAGGCGCGACGCACGGTTTACGCTCTGCCGTACTGAACCATA
TTCTGGACACGCTGCTTTCCATCCCTTCGCTCTTGCTGGCGATTATCGTCGTGGCATTTGCCGGCCCACATCTGTCACAC
GCGATGTTTGCCGTCTGGCTGGCCCTGTTGCCGCGAATGGTACGTTCCGTCTATAGCATGGTGCATGATGAACTGGAAAA
AGAGTACGTCATTGCCGCCCGTCTGGATGGCGCGACAACGCTGAATATTCTGTGGTTCGCCATTTTACCGAATATTACCG
CCGGTCTGGTCACCGAAATTACCCGGGCGCTGTCGATGGCGATTCTGGACATCGCCGCGCTGGGATTTTTAGATCTCGGC
GCGCAGCTTCCCTCTCCTGAATGGGGCGCCATGTTGGGAGATGCGCTGGAGCTAATCTATGTCGCGCCGTGGACCGTTAT
GCTACCCGGCGCGGCGATAACGCTCAGTGTTTTACTGGTAAACCTGCTCGGAGATGGGATTCGTCGTGCGATTATTGCGG
GGGTGGAATAA

Upstream 100 bases:

>100_bases
AGTGCACAAAATTAAAACCCCAATGCTCGATAACTAATTGATAATGTTTTAAAATTTCAAAAGACATAAAGCATGGTAAA
CAAAAATAAAACGAGTAAAT

Downstream 100 bases:

>100_bases
TGCCGTTACTGGATATCCGCAATCTCACCATTGAATTTAAAACCAGCGAAGGTTGGGTAAAAGCGGTCGATCGCGTCAGT
ATGACATTAAGCGAAGGCGA

Product: peptide transport system permease SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCIFGGWIAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFIVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSH
AMFAVWLALLPRMVRSVYSMVHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLSVLLVNLLGDGIRRAIIAGVE

Sequences:

>Translated_296_residues
MPYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCIFGGWIAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFIVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSH
AMFAVWLALLPRMVRSVYSMVHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLSVLLVNLLGDGIRRAIIAGVE
>Mature_295_residues
PYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCIFGGWIAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTD
DLGRDVLSRLLSGAAPTVGGAFIVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSHA
MFAVWLALLPRMVRSVYSMVHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVTEITRALSMAILDIAALGFLDLGA
QLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLSVLLVNLLGDGIRRAIIAGVE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=94.5945945945946, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=40.9722222222222, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI1787054, Length=283, Percent_Identity=34.2756183745583, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787760, Length=248, Percent_Identity=36.2903225806452, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=30.2904564315353, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787498, Length=275, Percent_Identity=26.9090909090909, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31549; Mature: 31417

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCIFGGWIAPYGIDQQFLG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFIVTLAATLCGLVLGVVA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSHAMFAVWLALLPRMVRSVYSM
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLSVLLVNLLGDGIRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCIFGGWIAPYGIDQQFLG
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFIVTLAATLCGLVLGVVA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSHAMFAVWLALLPRMVRSVYSM
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLSVLLVNLLGDGIRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]