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The map label for this gene is speA [H]

Identifier: 194735932

GI number: 194735932

Start: 3148924

End: 3150822

Strand: Reverse

Name: speA [H]

Synonym: SeSA_A3260

Alternate gene names: 194735932

Gene position: 3150822-3148924 (Counterclockwise)

Preceding gene: 194734213

Following gene: 194735567

Centisome position: 66.91

GC content: 55.61

Gene sequence:

>1899_bases
ATGAGCTCCCAGGAAGCCAGCAAGATGCTGCGCACTTACAATATTGCCTGGTGGGGCAATAACTACTACGACGTCAACGA
GCTGGGCCATATTAGCGTATGCCCCGATCCCGACGTACCGGAAGCGCGTGTCGATCTTGCCAAACTGGTGAAAGCGCGCG
AAGCGCAAGGTCAGCGTCTGCCGGCGCTGTTTTGCTTCCCGCAGATCCTGCAACACCGTTTGCGTTCAATTAACGCGGCG
TTTAAGCGTGCGCGTGAATCTTACGGTTATAACGGCGACTACTTCCTCGTTTATCCGATTAAGGTCAATCAGCATCGCCG
CGTGATCGAGTCCCTTATCCATTCCGGTGAACCGTTGGGGCTGGAAGCGGGGTCAAAAGCGGAATTGATGGCGGTGCTGG
CGCATGCCGGCATGACCCGTAGCGTGATCGTCTGTAATGGTTATAAAGACCGTGAATACATTCGGCTGGCGCTGATTGGC
GAGAAGATGGGCCATAAGGTTTATCTGGTCATCGAAAAGATGTCTGAAATCGCGATTGTGCTGGAAGAAGCCGAGCGCCT
GAACGTGGTTCCTCGTCTGGGCGTGCGTGCGCGTCTGGCCTCTCAGGGATCCGGTAAGTGGCAATCCTCCGGCGGCGAAA
AATCAAAATTCGGCCTGGCGGCGACCCAGGTGCTGCAACTGGTGGAGACCCTGCGTGACGCCGGGCGCCTGGACAGTTTG
CAACTGTTGCACTTCCACCTGGGATCGCAGATGGCGAACATTCGCGATATCGCGACCGGCGTGCGCGAGTCCGCGCGTTT
CTATGTTGAGCTGCATAAGCTGGGCGTGAATATCCAGTGCTTCGACGTGGGCGGCGGTCTGGGCGTGGATTATGAAGGTA
CCCGCTCGCAGTCCGACTGTTCGGTGAACTATGGCCTGAACGAATATGCCAATAACATCATCTGGGCGATTGGCGATGCC
TGCGAAGAGCATGGTTTACCGCATCCGACGGTGATTACCGAGTCTGGCCGCGCCGTCACTGCGCACCATACGGTACTGGT
CTCTAACATTATCGGCGTGGAGCGTAACGAATACACGGATCCGACTGCCCCTGCTGAAGATGCGCCGCGCGCGCTGCAAA
ATCTCTGGGAAACCTGGCAGGAGATGCATAAGCCTGGCACCCGCCGCTCGCTGCGTGAATGGCTGCATGATAGCCAAATG
GATCTGCACGATATTCATATCGGCTACTCTTCCGGCGCGTTTAGTTTGCAGGAGCGCGCCTGGGCGGAGCAACTTTATCT
CAGCATGTGCCATGAAGTGCAGAAGCAACTGGACCCGCAAAACCGTGCGCATCGTCCGATTATCGACGAACTGCAAGAGC
GAATGGCGGACAAAATGTACGTCAACTTCTCGCTGTTCCAGTCAATGCCGGACGCGTGGGGAATCGATCAGCTCTTCCCG
GTACTGCCGCTGGAAGGGTTAGATCAGGTACCGGAACGTCGTGCCGTGCTGCTGGATATTACTTGTGATTCCGATGGCGC
TATTGACCACTATATCGATGGCGACGGTATCGCCACGACGATGCCGATGCCGGAATACGATCCAGAGAATCCGCCGATGC
TCGGCTTCTTTATGGTCGGCGCTTATCAGGAGATCCTCGGTAACATGCACAACCTGTTTGGCGATACTGAAGCGGTTGAC
GTGTTTGTCTTCCCGGATGGTAGCGTCGAGGTTGAGCTGTCGGACGAAGGCGATACCGTTGCGGATATGCTGCAATATGT
GCAACTGGATCCGAAAACGCTGTTAACGCATTTCCGCGACCAGGTAAAACAGACGGATCTGGACGATGCGTTGCAGCAGC
AGTTCCTTGAGGAATTTGAAGCGGGACTGTACGGTTATACTTATCTTGAAGATGAGTAG

Upstream 100 bases:

>100_bases
CTAATAAAAATTGAGGTTCGCTATGTCTGACGACATGTCTATGGGTTCGCCTTCGTCAGCAGGCGAACAGGGTGTACTAC
GCTCCATGCAGGAGGTTGCA

Downstream 100 bases:

>100_bases
CCGTTGATGCCCGGTGGCGCTGCGCTTACCGGGCCTACGAATGCAGGCTGGATAAGGTAAAGCCACCACCCGGCAGAATG
CTATACTCACTTGAACCCGT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAA
FKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIG
EKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSL
QLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDA
CEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQM
DLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFP
VLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVD
VFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE

Sequences:

>Translated_632_residues
MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAA
FKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIG
EKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSL
QLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDA
CEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQM
DLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFP
VLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVD
VFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
>Mature_631_residues
SSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAF
KRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGE
KMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQ
LLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDAC
EEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMD
LHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPV
LPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDV
FVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=632, Percent_Identity=97.7848101265823, Blast_Score=1290, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71164; Mature: 71033

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRL
CCCHHHHHHHHHEEEEEECCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
PALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCCC
LEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIV
CCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEHHHHCCEEEEEEEHHHHHHHH
LEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSL
HHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
QLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDC
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCEEEEEECCCCCCCCCCCCCCCCCC
SVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTD
EEECCHHHHHCCEEEEECHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHCCCCCCCCC
PTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHH
WAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHCCCCCCCHHHHHH
VLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
CCCCCCHHCCCCCCEEEEEEEECCCCCEEEEECCCCCEEECCCCCCCCCCCCEEEHHHHH
AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRD
HHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHH
QVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRL
CCHHHHHHHHHEEEEEECCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
PALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCCC
LEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIV
CCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEHHHHCCEEEEEEEHHHHHHHH
LEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSL
HHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
QLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDC
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCEEEEEECCCCCCCCCCCCCCCCCC
SVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTD
EEECCHHHHHCCEEEEECHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHCCCCCCCCC
PTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHH
WAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFP
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHCCCCCCCHHHHHH
VLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
CCCCCCHHCCCCCCEEEEEEEECCCCCEEEEECCCCCEEECCCCCCCCCCCCEEEHHHHH
AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRD
HHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHH
QVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]