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The map label for this gene is sgcR [H]

Identifier: 194735462

GI number: 194735462

Start: 1677281

End: 1678078

Strand: Direct

Name: sgcR [H]

Synonym: SeSA_A1735

Alternate gene names: 194735462

Gene position: 1677281-1678078 (Clockwise)

Preceding gene: 194738190

Following gene: 194737542

Centisome position: 35.62

GC content: 51.75

Gene sequence:

>798_bases
ATGCTGATGAGCCAACAGCGCCCCGACCGTATCAAACAGATGTTGCATTACCTTTGGCAACACAGGCACCTCTCAACACA
ACAAGCTATTGAGCTTTTTGGCTATGCAGAGGCAACCGTGCGCCGGGATTTTCACTATATCGCCAGCCGTTATCCCGGAA
TGGTTCGCGGCCATGGTTGTATTGACTTCGACGACAGTACGGAAGATAAAGAATATGTTTTTGACGTTAAGCGAACGTTA
CAAAGCGAGGCGAAACGCGAAATCGCTGCCCTCGCCCGCACGTTCATCAAGGATGGAGACTGCTTTTTTCTCGACTCCGG
CTCCACCTGTCTGGAACTGGCAAAATGTCTGGTTGACGCCAAAGTAAAAGTCATTTGCAATGACATCAAAATCGCTAATG
AACTGGGTGGCTTCCCACACGTAGAGAGCTACATTATCGGCGGACTGATCCGCCCCGGCTACTTTTCGGTGGGCGAGAGT
CTGGCGCTGGAGATGATTAACGCCTTTGCCGTTGAACGCGCCTTTATCTCCTGCGATGCGCTGTCGATTGAAACGGGCAT
CACCAACGCTACCATGTTTGAAGTGGGCGTTAAAACGCGCATTATTCAGCGCTCACGCGAGGTCATATTGATGGCCGATC
ACTCAAAGTTTGATACTGTAGAACCCCATGCGGTGGCGACGCTGTCCTGTATTACTACTATTCTTAGCGACAGTGCGCTC
CCGTCTGCTATCGCCCGACGTTATCAGCAGGCGGGATGCCGTCTCATCATGTCAACCCCCTCATCAGGAGCGCGTTAA

Upstream 100 bases:

>100_bases
CGCCGCAGGCGCACAGCATCTGGTGATTGGCCGGGCGTTATTCACGACGGCGAACTATGATGTGACGTTGTCACAATTCA
CCGCGCTATAAAGGAGTCAT

Downstream 100 bases:

>100_bases
TGGACATCAGGCACATGAACAAAACCCATCTGGAGCACTGGCGCGGATTGCGAAAACAGCTCTGGCCTGATCACCCGGAC
GACGCCCATCTGGCGGACGG

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLMSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHYIASRYPGMVRGHGCIDFDDSTEDKEYVFDVKRTL
QSEAKREIAALARTFIKDGDCFFLDSGSTCLELAKCLVDAKVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGES
LALEMINAFAVERAFISCDALSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTVEPHAVATLSCITTILSDSAL
PSAIARRYQQAGCRLIMSTPSSGAR

Sequences:

>Translated_265_residues
MLMSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHYIASRYPGMVRGHGCIDFDDSTEDKEYVFDVKRTL
QSEAKREIAALARTFIKDGDCFFLDSGSTCLELAKCLVDAKVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGES
LALEMINAFAVERAFISCDALSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTVEPHAVATLSCITTILSDSAL
PSAIARRYQQAGCRLIMSTPSSGAR
>Mature_265_residues
MLMSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHYIASRYPGMVRGHGCIDFDDSTEDKEYVFDVKRTL
QSEAKREIAALARTFIKDGDCFFLDSGSTCLELAKCLVDAKVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGES
LALEMINAFAVERAFISCDALSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTVEPHAVATLSCITTILSDSAL
PSAIARRYQQAGCRLIMSTPSSGAR

Specific function: Putative transcriptional regulator for the sgcREAQCX region [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790753, Length=255, Percent_Identity=89.8039215686275, Blast_Score=486, Evalue=1e-139,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=27.34375, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=24, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082344, Length=250, Percent_Identity=22.4, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789829, Length=240, Percent_Identity=24.1666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=23.1441048034935, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI226510968, Length=215, Percent_Identity=28.8372093023256, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787063, Length=244, Percent_Identity=25.4098360655738, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787540, Length=234, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=25, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29598; Mature: 29598

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHYIASRYPGMVRGHGC
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCE
IDFDDSTEDKEYVFDVKRTLQSEAKREIAALARTFIKDGDCFFLDSGSTCLELAKCLVDA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
KVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGESLALEMINAFAVERAFISCDA
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTVEPHAVATLSCITTILSDSAL
EEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC
PSAIARRYQQAGCRLIMSTPSSGAR
HHHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure
MLMSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHYIASRYPGMVRGHGC
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCE
IDFDDSTEDKEYVFDVKRTLQSEAKREIAALARTFIKDGDCFFLDSGSTCLELAKCLVDA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
KVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGESLALEMINAFAVERAFISCDA
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTVEPHAVATLSCITTILSDSAL
EEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC
PSAIARRYQQAGCRLIMSTPSSGAR
HHHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]