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The map label for this gene is flhA [H]

Identifier: 194735453

GI number: 194735453

Start: 1986092

End: 1988170

Strand: Reverse

Name: flhA [H]

Synonym: SeSA_A2068

Alternate gene names: 194735453

Gene position: 1988170-1986092 (Counterclockwise)

Preceding gene: 194734592

Following gene: 194737915

Centisome position: 42.22

GC content: 56.04

Gene sequence:

>2079_bases
ATGGCTAATCTGGTCGCGATGCTGCGCCTGCCCAGCAACCTGAAATCGACGCAATGGCAAATTCTTGCCGGGCCGATCCT
CATTCTGCTGATTTTGTCGATGATGGTGCTGCCGCTACCTGCTTTTATCCTCGACTTATTGTTTACCTTTAATATTGCGC
TATCGATTATGGTGCTGCTGGTGGCGATGTTTACCCAGCGTACTCTGGATTTTGCCGCGTTTCCGACCATTCTGCTGTTT
ACCACGCTACTGCGTCTGGCGCTTAACGTAGCCTCAACGCGCATTATTTTGATGGAAGGGCATACCGGCGCGGCGGCGGC
GGGAAAGGTGGTGGAGGCGTTTGGTCATTTCCTGGTCGGCGGTAACTTCGCGATCGGGATTGTGGTTTTTATCATCCTCG
TCATTATCAACTTCATGGTCATCACCAAAGGCGCCGGACGTATTGCCGAAGTCGGCGCGCGCTTTGTGCTGGACGGTATG
CCCGGCAAGCAAATGGCGATTGACGCCGATCTTAATGCCGGTCTGATTGGTGAAGACGAGGCCAAAAAACGGCGTTCGGA
AGTCACTCAGGAAGCCGATTTCTACGGCTCGATGGACGGGGCAAGTAAATTTGTGCGCGGCGACGCCATCGCCGGTATTC
TCATCATGGTCATTAACGTGGTAGGCGGGCTGCTGGTCGGCGTATTGCAGCACGGAATGAGCATAGGCAGCGCGGCGGAA
AGCTACACCCTGCTGACCATTGGCGACGGCCTGGTCGCCCAGATCCCGGCGCTGGTTATCTCCACGGCGGCGGGCGTCAT
TGTGACCCGCGTCAGTACCGATCAGGATGTAGGCGAGCAGATGGTTGGCCAACTGTTCAGTAATCCAAGGGTGATGCTGC
TGGCGGCGGCGGTGCTGGGGCTGCTTGGCATGGTGCCAGGAATGCCTAACCTGGTATTTTTACTCTTTACCGCCGCTTTG
CTCGGCCTGGCATGGTGGCTGCGCGGGCGTGAAGAAAAAGCGCCGGAGGAGCCGCAGCCGGTAAAAATGCCGGAAAATAA
CTCGGTGGTCGAAGCCACCTGGAATGACGTACAGCTTGAGGATTCACTGGGGATGGAAGTGGGCTACCGCCTGATCCCGA
TGGTGGATTTTCAACAGGATGGCGAATTGCTCGGACGTATTCGCAGTATTCGTAAAAAATTCGCTCAGGATATGGGGTTC
CTGCCGCCGGTTGTCCATATTCGCGACAATATGGATTTACAGCCTGCGCGCTACCGTATTTTGATGAAAGGGGTAGAGAT
TGGCAGCGGGGACGCCTATCCGGGACGCTGGCTGGCTATTAACCCCGGCACGGCGGCGGGAACGCTACCGGGTGAGAAAA
CCGTCGATCCAGCTTTTGGCCTTGATGCCATCTGGATTGAAAGCGCCCTGAAAGAGCAGGCGCAAATTCAGGGCTTTACC
GTTGTTGAAGCCAGTACCGTTGTGGCGACGCACCTTAACCACTTGATTGGCCAATTCTCCGCCGAACTGTTTGGCCGCCA
GGAAGCGCAGCAACTGTTGGATCGTGTCTCTCAGGAGATGCCTAAACTCACGGAAGATCTGGTCCCCGGCGTCGTGACCC
TCACGACTTTACATAAAGTCCTGCAAAACTTACTGGCGGAAAAAGTCCCGATTCGCGATATGCGCACCATTCTGGAAACG
CTGGCGGAACATGCGCCGTTACAAAGCGATCCGCATGAATTAACCGCCGTGGTACGCGTGGCATTAGGACGAGCGATTAC
GCAACAGTGGTTCCCCGGTAATGAAGAAGTGCAGGTGATTGGCCTGGATACCGCGCTGGAGCGTTTGCTGCTTCAGGCAT
TGCAGGGCGGCGGTGGACTTGAGCCGGGGTTGGCGGATCGCCTGCTGGCGCAGACGCAAGAGGCGCTTTCTCGCCAGGAG
ATGCTTGGCGCGCCGCCGGTATTACTGGTTAACCATGCGCTACGTCCATTATTGTCCCGCTTTTTGCGGCGCAGTTTACC
GCAGCTGGTGGTGTTGTCGAACCTTGAGCTTTCCGATAACCGTCATATCCGCATGACGGCGACCATTGGAGGAAAATAA

Upstream 100 bases:

>100_bases
CAGCTTAAACGCTGGCGGCTTGCGGGCGGGCAACGTCCTCCACAACCTGAGAACCTTCCGGTGCCAGAAGCGCTGGATTT
TATGAACGAGAAGAATACTG

Downstream 100 bases:

>100_bases
TGCGTAAATGGCTGGCGTTGTTGCTCTTTCCCCTGACGGTTCAGGCCGCAGGCGAAGGCGCGTGGCAGGATAGCGGTATG
GGCGTAACCTTAAATTACCG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
TTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVVGGLLVGVLQHGMSIGSAAE
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVGQLFSNPRVMLLAAAVLGLLGMVPGMPNLVFLLFTAAL
LGLAWWLRGREEKAPEEPQPVKMPENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRKKFAQDMGF
LPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEKTVDPAFGLDAIWIESALKEQAQIQGFT
VVEASTVVATHLNHLIGQFSAELFGRQEAQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKVLQNLLAEKVPIRDMRTILET
LAEHAPLQSDPHELTAVVRVALGRAITQQWFPGNEEVQVIGLDTALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQE
MLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRHIRMTATIGGK

Sequences:

>Translated_692_residues
MANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
TTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVVGGLLVGVLQHGMSIGSAAE
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVGQLFSNPRVMLLAAAVLGLLGMVPGMPNLVFLLFTAAL
LGLAWWLRGREEKAPEEPQPVKMPENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRKKFAQDMGF
LPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEKTVDPAFGLDAIWIESALKEQAQIQGFT
VVEASTVVATHLNHLIGQFSAELFGRQEAQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKVLQNLLAEKVPIRDMRTILET
LAEHAPLQSDPHELTAVVRVALGRAITQQWFPGNEEVQVIGLDTALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQE
MLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRHIRMTATIGGK
>Mature_691_residues
ANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFT
TLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGMP
GKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVVGGLLVGVLQHGMSIGSAAES
YTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVGQLFSNPRVMLLAAAVLGLLGMVPGMPNLVFLLFTAALL
GLAWWLRGREEKAPEEPQPVKMPENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRKKFAQDMGFL
PPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEKTVDPAFGLDAIWIESALKEQAQIQGFTV
VEASTVVATHLNHLIGQFSAELFGRQEAQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKVLQNLLAEKVPIRDMRTILETL
AEHAPLQSDPHELTAVVRVALGRAITQQWFPGNEEVQVIGLDTALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQEM
LGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRHIRMTATIGGK

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=692, Percent_Identity=95.2312138728324, Blast_Score=1296, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74850; Mature: 74719

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLL
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFTTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHC
GNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVVGGLLVGVLQHGMSIGSAAE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVGQLFSNPRVMLLAAAVLG
CEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LLGMVPGMPNLVFLLFTAALLGLAWWLRGREEKAPEEPQPVKMPENNSVVEATWNDVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEC
DSLGMEVGYRLIPMVDFQQDGELLGRIRSIRKKFAQDMGFLPPVVHIRDNMDLQPARYRI
HHCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHH
LMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEKTVDPAFGLDAIWIESALKEQAQIQGFT
HHHCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHLIGQFSAELFGRQEAQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLAEKVPIRDMRTILETLAEHAPLQSDPHELTAVVRVALGRAITQQWFPGNEEVQVI
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GLDTALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSR
EHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLRRSLPQLVVLSNLELSDNRHIRMTATIGGK
HHHHCCCCEEECCCCEECCCCEEEEEEECCCC
>Mature Secondary Structure 
ANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFTTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHC
GNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVVGGLLVGVLQHGMSIGSAAE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVGQLFSNPRVMLLAAAVLG
CEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LLGMVPGMPNLVFLLFTAALLGLAWWLRGREEKAPEEPQPVKMPENNSVVEATWNDVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEC
DSLGMEVGYRLIPMVDFQQDGELLGRIRSIRKKFAQDMGFLPPVVHIRDNMDLQPARYRI
HHCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHH
LMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEKTVDPAFGLDAIWIESALKEQAQIQGFT
HHHCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHLIGQFSAELFGRQEAQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLAEKVPIRDMRTILETLAEHAPLQSDPHELTAVVRVALGRAITQQWFPGNEEVQVI
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GLDTALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSR
EHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLRRSLPQLVVLSNLELSDNRHIRMTATIGGK
HHHHCCCCEEECCCCEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]