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The map label for this gene is sufC [H]

Identifier: 194735450

GI number: 194735450

Start: 1418165

End: 1418911

Strand: Direct

Name: sufC [H]

Synonym: SeSA_A1468

Alternate gene names: 194735450

Gene position: 1418165-1418911 (Clockwise)

Preceding gene: 194735936

Following gene: 194737662

Centisome position: 30.12

GC content: 52.88

Gene sequence:

>747_bases
ATGTTAAGCATTAAAGATTTACAGGTCAGTGTGGAAGAAAAAGCGATTTTGCGTGGCCTGAATCTGGAGATTCGCCCCGG
CGAAGTTCACGCCATTATGGGGCCGAACGGTTCCGGGAAAAGCACGCTCTCCGCCACCCTGGCGGGACGTGAAGATTACG
AGGTCACCGGCGGCTCGGTTACGTTCAAAGGTAAAGATCTGCTTGAACTGTCGCCGGAGGAACGGGCGGGCGAAGGGATT
TTTATGGCCTTCCAGTACCCGGTAGAAATCCCCGGCGTCAGTAACCAGTTTTTCCTGCAAACCGCGCTGAATGCCGTGCG
CGCCTACCGCGGGCAGACGTCGTTGGATCGCTTTGATTTTCAGGATCTGATGGAAGAAAAGATCGCATTGCTGAAAATGC
CGGAAGATTTGCTGACCCGTTCGGTAAACGTCGGTTTTTCCGGCGGGGAGAAAAAGCGCAATGATATTTTGCAAATGGCG
GTGCTGGAGCCGGAACTGTGCATCCTTGATGAGTCGGACTCCGGACTGGATATCGATGCGTTGAAAATTGTGGCGGAAGG
CGTCAACGCGTTACGCGACGATAAACGCGCTTTTATTATCGTGACCCACTATCAGCGCATACTGGACTACATCAAGCCTG
ATTACGTCCATGTCCTCTACCAGGGGCGAATTGTCCGATCCGGCGATTTTACTCTGGTCAAACAACTGGAGGAGCAGGGT
TATGGCTGGCTTACCGAACAGCAGTAA

Upstream 100 bases:

>100_bases
GACGTTTTCTCGGAACTGCCGCTGGAGTTTGCCGTTGAAGCGCAAAAACTGCTGGCGATTAGCCTTGAGCACAGCGTCGG
TTAATGATGAAGGAAAACCC

Downstream 100 bases:

>100_bases
AGCGCTACAGCAATGGCAGCATCTCTTTGAAGAAAAAGGAGTAAGTCGAACTGAGCAGGCAAGACAACATTTACAACAGA
TGTTACGTCTGGGATTGCCG

Product: cysteine desulfurase ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLSIKDLQVSVEEKAILRGLNLEIRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGSVTFKGKDLLELSPEERAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRAYRGQTSLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVRSGDFTLVKQLEEQG
YGWLTEQQ

Sequences:

>Translated_248_residues
MLSIKDLQVSVEEKAILRGLNLEIRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGSVTFKGKDLLELSPEERAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRAYRGQTSLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVRSGDFTLVKQLEEQG
YGWLTEQQ
>Mature_248_residues
MLSIKDLQVSVEEKAILRGLNLEIRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGSVTFKGKDLLELSPEERAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRAYRGQTSLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVRSGDFTLVKQLEEQG
YGWLTEQQ

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=228, Percent_Identity=27.6315789473684, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI9961252, Length=241, Percent_Identity=26.5560165975104, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4505771, Length=241, Percent_Identity=26.5560165975104, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI9961250, Length=241, Percent_Identity=26.5560165975104, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787972, Length=248, Percent_Identity=92.3387096774193, Blast_Score=475, Evalue=1e-136,
Organism=Escherichia coli, GI48994883, Length=246, Percent_Identity=29.6747967479675, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789864, Length=240, Percent_Identity=25.8333333333333, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788761, Length=228, Percent_Identity=26.7543859649123, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786698, Length=204, Percent_Identity=26.9607843137255, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=239, Percent_Identity=28.0334728033473, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17558664, Length=246, Percent_Identity=27.2357723577236, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=237, Percent_Identity=29.1139240506329, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI85816269, Length=248, Percent_Identity=27.8225806451613, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580553, Length=248, Percent_Identity=27.8225806451613, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85724864, Length=248, Percent_Identity=27.8225806451613, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580555, Length=248, Percent_Identity=27.8225806451613, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85726357, Length=241, Percent_Identity=26.1410788381743, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27716; Mature: 27716

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIKDLQVSVEEKAILRGLNLEIRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGSV
CCCCCHHEEEHHHHHHHHCCCEEECCCCEEEEECCCCCCCCEEEEEECCCCCCEECCCEE
TFKGKDLLELSPEERAGEGIFMAFQYPVEIPGVSNQFFLQTALNAVRAYRGQTSLDRFDF
EECCCCEEEECCCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
QDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDA
HHHHHHHHHHHCCCHHHHHCEECCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHH
LKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVRSGDFTLVKQLEEQG
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCEEEEEEECEEEECCCHHHHHHHHHCC
YGWLTEQQ
CCEECCCC
>Mature Secondary Structure
MLSIKDLQVSVEEKAILRGLNLEIRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGSV
CCCCCHHEEEHHHHHHHHCCCEEECCCCEEEEECCCCCCCCEEEEEECCCCCCEECCCEE
TFKGKDLLELSPEERAGEGIFMAFQYPVEIPGVSNQFFLQTALNAVRAYRGQTSLDRFDF
EECCCCEEEECCCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
QDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDA
HHHHHHHHHHHCCCHHHHHCEECCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHH
LKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVRSGDFTLVKQLEEQG
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCEEEEEEECEEEECCCHHHHHHHHHCC
YGWLTEQQ
CCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]