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The map label for this gene is astC [H]

Identifier: 194735228

GI number: 194735228

Start: 1348866

End: 1350092

Strand: Direct

Name: astC [H]

Synonym: SeSA_A1398

Alternate gene names: 194735228

Gene position: 1348866-1350092 (Clockwise)

Preceding gene: 194734569

Following gene: 194735878

Centisome position: 28.64

GC content: 56.07

Gene sequence:

>1227_bases
ATGTCTCTGTCAGTTACGCGCGAAAACTTTGATGAATGGATGGTGCCGGTATATGTTCCCGCGCCTTTTATTCCTGTACG
CGGAGAAGGCTCACGCCTGTGGGATCAGCAGGAGAAAGAGTACATTGATTTTGCTGGCGGGATCGCGGTCAACGCATTGG
GACATGCGCATCCGGCGCTGCGCGAGGCGTTAAATGAACAGGCGAATCGCTTCTGGCATACCGGGAACGGTTACACCAAT
GAGCCGGCGCTGCGACTGGCGAAAAAACTGATCGACGCGACCTTCGCCGAACGCGTTTTCTTTTGTAATTCAGGCGCTGA
AGCAAATGAAGCAGCATTAAAACTGGCGCGCAAATATGCCCACGATCGTGCCGGCAACCATAAAAGCGGCATTGTGGCCT
TTAAAAACGCGTTCCATGGTCGCACGCTCTTTACCGTCAGCGCTGGCGGTCAACCCTCCTATTCACAGGACTTTGCGCCG
CTGCCGCCGGATATTCGTCATGCAGCCTATAACGATCTGAACTCCGCCAGCGCGCTAATTGATGACAATACCTGCGCCGT
GATCGTAGAGCCTGTGCAGGGCGAGGGCGGCGTGATCCCCGCCACGAAAGCTTTTTTGCAGGGGCTGCGTGAATTGTGCG
ACCGGCATCAGGCGTTACTGATTTTTGATGAGGTGCAGACGGGCGTCGGACGTACCGGCGAACTGTATGCATATATGCAT
TATGGCGTTACGCCCGATATCCTGACGACCGCTAAAGCGTTGGGTGGCGGCTTCCCGATCGGCGCGATGCTGACCACGCA
AGACTATGCCAGCGTTATGACGCCAGGCACGCATGGCACCACCTACGGCGGTAATCCGCTGGCGACGGCAGTTGCCGGAA
AAGTACTGGATATCATCAATACGCCGGAGATGCAAAACGGCGTCAGACAGCGCCACGATGCGTTTATTGAACGTCTAAAT
ACCATTAATGTACGTTTTGGCATGTTCAGTGAAATTCGCGGGCTGGGGCTACTGCTTGGCTGTGTGCTACAGACGGAGTT
TGCCGGAAAAGCCAAACTCATCGCCCAGGAAGCGGCAAAAGCAGGTGTGATGGTGCTCATCGCCGGCGGCGACGTGGTGC
GTTTTGCGCCAGCGTTAAATGTGAGCGACGAGGAGATAGCCACCGGGCTTGATCGTTTTGCCCTGGCGTGCGAACGCCTT
CAGACGGGAGGCGCACCATGCGGGTGA

Upstream 100 bases:

>100_bases
TTAACGCTGGCTGGCACGAATGCTGCAATCTACATTTACAGCGCAAACACTCATATTAATTAACATATAAATAACTTTAT
TTTTACCAAAAGAGGTCGCT

Downstream 100 bases:

>100_bases
TTCGTCCTGTCGAACATGCGGATATCGCCGCGCTGATGCAGCTTGCAGGCAAAACGGGCGGCGGCTTAACCTCGCTACCG
GCAAATGAAGCGACGCTGGC

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQEKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTN
EPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRAGNHKSGIVAFKNAFHGRTLFTVSAGGQPSYSQDFAP
LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLN
TINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERL
QTGGAPCG

Sequences:

>Translated_408_residues
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQEKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTN
EPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRAGNHKSGIVAFKNAFHGRTLFTVSAGGQPSYSQDFAP
LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLN
TINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERL
QTGGAPCG
>Mature_407_residues
SLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQEKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNE
PALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRAGNHKSGIVAFKNAFHGRTLFTVSAGGQPSYSQDFAPL
PPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHY
GVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNT
INVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQ
TGGAPCG

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=34.1269841269841, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=36.518771331058, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=26.7415730337079, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.2511848341232, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=26.5402843601896, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=27.906976744186, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=26.2790697674419, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=24.5327102803738, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=24.5327102803738, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=24.5327102803738, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788044, Length=405, Percent_Identity=84.4444444444444, Blast_Score=728, Evalue=0.0,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=62.2166246851385, Blast_Score=522, Evalue=1e-149,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.4170854271357, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=35.2941176470588, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1787560, Length=390, Percent_Identity=34.1025641025641, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=33.0128205128205, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786991, Length=316, Percent_Identity=33.5443037974684, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI25144271, Length=378, Percent_Identity=33.8624338624339, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=28.6697247706422, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=34.0579710144928, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=366, Percent_Identity=29.2349726775956, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=253, Percent_Identity=28.0632411067194, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=31.0975609756098, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=41.1167512690355, Blast_Score=287, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=33.175355450237, Blast_Score=216, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=325, Percent_Identity=29.8461538461538, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=358, Percent_Identity=26.2569832402235, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357415, Length=379, Percent_Identity=34.0369393139842, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=29.8206278026906, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.7052154195011, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI21356575, Length=363, Percent_Identity=29.7520661157025, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281366494, Length=437, Percent_Identity=23.7986270022883, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667139, Length=437, Percent_Identity=23.7986270022883, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667143, Length=437, Percent_Identity=23.7986270022883, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43822; Mature: 43691

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQEKEYIDFAGGIAVNALGHAHPAL
CCCCCCHHCHHHCEEEEEECCCEEEECCCCCHHCCHHHHHHHHHCCCCHHHHHHCCCHHH
REALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYA
HHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDRAGNHKSGIVAFKNAFHGRTLFTVSAGGQPSYSQDFAPLPPDIRHAAYNDLNSASALI
HHCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEE
DDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEE
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIIN
CCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
TPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAK
CCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGAPCG
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQEKEYIDFAGGIAVNALGHAHPAL
CCCCCHHCHHHCEEEEEECCCEEEECCCCCHHCCHHHHHHHHHCCCCHHHHHHCCCHHH
REALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYA
HHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDRAGNHKSGIVAFKNAFHGRTLFTVSAGGQPSYSQDFAPLPPDIRHAAYNDLNSASALI
HHCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEE
DDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEE
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIIN
CCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
TPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAK
CCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGAPCG
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA