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The map label for this gene is yqfA [H]

Identifier: 194735005

GI number: 194735005

Start: 3110551

End: 3111210

Strand: Reverse

Name: yqfA [H]

Synonym: SeSA_A3218

Alternate gene names: 194735005

Gene position: 3111210-3110551 (Counterclockwise)

Preceding gene: 194734498

Following gene: 194736338

Centisome position: 66.07

GC content: 50.45

Gene sequence:

>660_bases
ATGGTGCAAAAACCATTAATGACGCAGGGATATTCGCTGGCTGAGGAAATCGCCAACAGTATTAGCCACGGCATTGGATT
GGTATTTGGTATTGTCGGCCTGGTGCTGTTGTTGGTTCAGGCGGTAGAGGCGAATGCTGGTATGACGGCTATTGCCAGCT
ACAGTTTATATGGCGGGAGCATGATCCTGCTTTTTCTTGCCTCAACGCTTTATCATGCCATTCCTCATCAGCGGGCAAAA
ATCTGGTTAAAGAAATTTGATCACTGCGCTATCTATCTGCTCATTGCCGGAACCTATACGCCATTTCTGCTGGTAGGTCT
GGATTCGCCGCTGGCGCGCGGACTAATGATTGTGATCTGGAGCCTGGCGCTATTCGGTATCCTCTTCAAGTTGACGATTG
CGCACCGATTTAAAGTGCTTTCACTGGTTACGTATCTGGCAATGGGCTGGCTGTCGCTGATAGTGGTTTATCAGTTGGCG
ATTAAGCTGGCGATAGGCGGCGTGACGCTGCTGGCGGTAGGTGGCGTCGTTTACTCGCTGGGCGTAATTTTCTATGTTTG
CAAACGCATACCTTATAACCACGCCATCTGGCATGGCTTTGTGCTGGGTGGCAGCGTGTGCCACTTCCTGGCCATCTATT
TGTATGTGGGACAGGCGTAA

Upstream 100 bases:

>100_bases
ATTTTGCGAATTTATTTTAGCTAACATGTGTTCACTGGAACCATTCTCAGTTACGCTAGAGGCGCAGTTCATCGTTATGA
ACGTTTCTCCGGAGTAAGTT

Downstream 100 bases:

>100_bases
TTCCCGGATGCCCGTGCCGGATGGCGGCGCTGTCGCACCTTATCCGGCCTACGAGAATAGCACGTGCGAGCCTGATGGCG
TTGCGCTATCAGGCTATCCG

Product: hemolysin-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEANAGMTAIASYSLYGGSMILLFLASTLYHAIPHQRAK
IWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLA
IKLAIGGVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQA

Sequences:

>Translated_219_residues
MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEANAGMTAIASYSLYGGSMILLFLASTLYHAIPHQRAK
IWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLA
IKLAIGGVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQA
>Mature_219_residues
MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEANAGMTAIASYSLYGGSMILLFLASTLYHAIPHQRAK
IWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLA
IKLAIGGVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI52630445, Length=213, Percent_Identity=31.924882629108, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI154759275, Length=208, Percent_Identity=29.8076923076923, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI154759277, Length=232, Percent_Identity=26.7241379310345, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1789266, Length=219, Percent_Identity=91.324200913242, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI71996356, Length=217, Percent_Identity=31.7972350230415, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640324, Length=234, Percent_Identity=31.1965811965812, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23819; Mature: 23819

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEANAGMTAIASYSLYGGS
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHH
MILLFLASTLYHAIPHQRAKIWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
SLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLAIKLAIGGVTLLAVGGVVYSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEANAGMTAIASYSLYGGS
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHH
MILLFLASTLYHAIPHQRAKIWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
SLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLAIKLAIGGVTLLAVGGVVYSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]