Click here to switch to the map view.

The map label for this gene is cat2 [H]

Identifier: 194734587

GI number: 194734587

Start: 3176819

End: 3178144

Strand: Reverse

Name: cat2 [H]

Synonym: SeSA_A3293

Alternate gene names: 194734587

Gene position: 3178144-3176819 (Counterclockwise)

Preceding gene: 194738180

Following gene: 194737380

Centisome position: 67.49

GC content: 45.55

Gene sequence:

>1326_bases
ATGATGAATGTTAATGCAGCGTATGCCGAAAAATGCGTGACGCCTGACGAGGCGGTTACTTTAATTACCTCCGGCAGTCA
CCTCTCTATGGGAATGTTTGCAGCAGAGCCTCCAGCTTTGCTGAATGCGCTGGCAAAGCGAGCGAAAAGGGGAGAAATCA
ACGATCTGCGGGTTTACTGTTATGAAACAGCCAGCATTGCCGGGAACACTATTTTCCGTTATGAGCTAAGTGACTATATT
CATCTCTACAGTATGTTTATTACCGGTATTGAACGGGCTTTAATACGTCAGGGGATTGAGAGTTCCGGGCGAAAAATAGT
TAACTATGTACCTTCAAATTTTCATCAGGCGACGCGATTACTGGCTGATGATATTGGTATTGATACCTTTATTCACACCG
TGTCCCCTATGGATAAGTATGGCTATTTTAATTTTGGAACTGGAAACGATTATTCCACCCGGATTGCGAGGACAGCTAAA
AAGCTTATTGTCGAAGTTAACAAATATATGCCGCGCGTTCATGGAGAAGGTGCTGCAATCCATATTTCAGAAATTGACGC
CATTGTTGAAAACCATGTCCCTTTAATTGAACTACCAATACGTACTGCCGTAGCCGAAGATATTGCTATCAGTCAGATTA
TCGCCTCTCTTGTGCCAGATGGCGCTTGTCTCCAGATGGGGGTCGGCGCATTACCGGAGCTCATCTGTAATGCGCTCAAG
GAACATAATGATCTGGGGGTCCATACAGAGGCGCTGAATCCGGGGTTGGTAAGTTTGATTCAACAAGGCGTCGTTACCAA
CCAGCGTAAAAATATCGACCGGGGAATGTCTGTATTTACTTTTGCTATGGGACAAAAGGATATGTATGACTATCTCAACG
ACAACCCCTCTTTTTTTAGTCGGCCTGTCGATTATGTTAACGATCCGGGGATCATTGCGCAAAATGAGAATGTTGTCTCC
ATTAACGCTACCTTACAAATCGATCTCACTGGTGCCTGTAACTCTGAATATTTGCTTGGACACCAGTACAGTGCTTCAGG
AGGGCAATTGGATTTTGTCAGAGGCGCATATGCATCTAAAGGAGGTCGTTCCATTATTACGACCCGCTCAACGGCCGCGA
ATGATACGATTTCTCGTATTGTTCCCCGCCTTGAGGGGCCTGTAACAACCCCACGAACGGATACGCACTGGATAGTCACT
GAATTTGGCTCCGTAAACCTGAAGGGGCTCTCTTCAACCGAGCGTGCGCTCAGGATCATTGAATTGGCGCATCCCAATTT
TCGGCAGCAACTTAGAGTAGATGCAAAAAAAATGCATCTGATTTAA

Upstream 100 bases:

>100_bases
AGAGGTCATGCGCTTCGAACGAACAATGTTAGTTTATTGCTGTGGATGTTCGCCTGAAGAAGACGCCGCTTATTGAGAAA
TCGCCCTGAGGTTTAGAGTC

Downstream 100 bases:

>100_bases
AAGTAGGTTAATGCTATTTTTAATGTAGCATCCCCAAAATATAAACATCATGAGTCTATTCAAATGATAATTGACAGAAT
TGATCACCTTGTATTAACGG

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MMNVNAAYAEKCVTPDEAVTLITSGSHLSMGMFAAEPPALLNALAKRAKRGEINDLRVYCYETASIAGNTIFRYELSDYI
HLYSMFITGIERALIRQGIESSGRKIVNYVPSNFHQATRLLADDIGIDTFIHTVSPMDKYGYFNFGTGNDYSTRIARTAK
KLIVEVNKYMPRVHGEGAAIHISEIDAIVENHVPLIELPIRTAVAEDIAISQIIASLVPDGACLQMGVGALPELICNALK
EHNDLGVHTEALNPGLVSLIQQGVVTNQRKNIDRGMSVFTFAMGQKDMYDYLNDNPSFFSRPVDYVNDPGIIAQNENVVS
INATLQIDLTGACNSEYLLGHQYSASGGQLDFVRGAYASKGGRSIITTRSTAANDTISRIVPRLEGPVTTPRTDTHWIVT
EFGSVNLKGLSSTERALRIIELAHPNFRQQLRVDAKKMHLI

Sequences:

>Translated_441_residues
MMNVNAAYAEKCVTPDEAVTLITSGSHLSMGMFAAEPPALLNALAKRAKRGEINDLRVYCYETASIAGNTIFRYELSDYI
HLYSMFITGIERALIRQGIESSGRKIVNYVPSNFHQATRLLADDIGIDTFIHTVSPMDKYGYFNFGTGNDYSTRIARTAK
KLIVEVNKYMPRVHGEGAAIHISEIDAIVENHVPLIELPIRTAVAEDIAISQIIASLVPDGACLQMGVGALPELICNALK
EHNDLGVHTEALNPGLVSLIQQGVVTNQRKNIDRGMSVFTFAMGQKDMYDYLNDNPSFFSRPVDYVNDPGIIAQNENVVS
INATLQIDLTGACNSEYLLGHQYSASGGQLDFVRGAYASKGGRSIITTRSTAANDTISRIVPRLEGPVTTPRTDTHWIVT
EFGSVNLKGLSSTERALRIIELAHPNFRQQLRVDAKKMHLI
>Mature_441_residues
MMNVNAAYAEKCVTPDEAVTLITSGSHLSMGMFAAEPPALLNALAKRAKRGEINDLRVYCYETASIAGNTIFRYELSDYI
HLYSMFITGIERALIRQGIESSGRKIVNYVPSNFHQATRLLADDIGIDTFIHTVSPMDKYGYFNFGTGNDYSTRIARTAK
KLIVEVNKYMPRVHGEGAAIHISEIDAIVENHVPLIELPIRTAVAEDIAISQIIASLVPDGACLQMGVGALPELICNALK
EHNDLGVHTEALNPGLVSLIQQGVVTNQRKNIDRGMSVFTFAMGQKDMYDYLNDNPSFFSRPVDYVNDPGIIAQNENVVS
INATLQIDLTGACNSEYLLGHQYSASGGQLDFVRGAYASKGGRSIITTRSTAANDTISRIVPRLEGPVTTPRTDTHWIVT
EFGSVNLKGLSSTERALRIIELAHPNFRQQLRVDAKKMHLI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=474, Percent_Identity=24.6835443037975, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538151, Length=442, Percent_Identity=33.0316742081448, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI32563853, Length=436, Percent_Identity=35.7798165137615, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI21358615, Length=428, Percent_Identity=35.0467289719626, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48464; Mature: 48464

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNVNAAYAEKCVTPDEAVTLITSGSHLSMGMFAAEPPALLNALAKRAKRGEINDLRVYC
CCCCCHHHHHHCCCCCCEEEEEECCCCCEECEECCCCHHHHHHHHHHHHCCCCCCEEEEE
YETASIAGNTIFRYELSDYIHLYSMFITGIERALIRQGIESSGRKIVNYVPSNFHQATRL
EEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCHHHHHHHH
LADDIGIDTFIHTVSPMDKYGYFNFGTGNDYSTRIARTAKKLIVEVNKYMPRVHGEGAAI
HHHHCCHHHHHHHCCCHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
HISEIDAIVENHVPLIELPIRTAVAEDIAISQIIASLVPDGACLQMGVGALPELICNALK
EHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
EHNDLGVHTEALNPGLVSLIQQGVVTNQRKNIDRGMSVFTFAMGQKDMYDYLNDNPSFFS
CCCCCCCCHHCCCHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCHHHHHHHCCCHHHHC
RPVDYVNDPGIIAQNENVVSINATLQIDLTGACNSEYLLGHQYSASGGQLDFVRGAYASK
CCHHHCCCCCEEECCCCEEEEEEEEEEEEECCCCCCEEECEEECCCCCCEEEHHCHHHCC
GGRSIITTRSTAANDTISRIVPRLEGPVTTPRTDTHWIVTEFGSVNLKGLSSTERALRII
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHH
ELAHPNFRQQLRVDAKKMHLI
HHCCCCHHHHHHHCHHHHCCC
>Mature Secondary Structure
MMNVNAAYAEKCVTPDEAVTLITSGSHLSMGMFAAEPPALLNALAKRAKRGEINDLRVYC
CCCCCHHHHHHCCCCCCEEEEEECCCCCEECEECCCCHHHHHHHHHHHHCCCCCCEEEEE
YETASIAGNTIFRYELSDYIHLYSMFITGIERALIRQGIESSGRKIVNYVPSNFHQATRL
EEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCHHHHHHHH
LADDIGIDTFIHTVSPMDKYGYFNFGTGNDYSTRIARTAKKLIVEVNKYMPRVHGEGAAI
HHHHCCHHHHHHHCCCHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
HISEIDAIVENHVPLIELPIRTAVAEDIAISQIIASLVPDGACLQMGVGALPELICNALK
EHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
EHNDLGVHTEALNPGLVSLIQQGVVTNQRKNIDRGMSVFTFAMGQKDMYDYLNDNPSFFS
CCCCCCCCHHCCCHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCHHHHHHHCCCHHHHC
RPVDYVNDPGIIAQNENVVSINATLQIDLTGACNSEYLLGHQYSASGGQLDFVRGAYASK
CCHHHCCCCCEEECCCCEEEEEEEEEEEEECCCCCCEEECEEECCCCCCEEEHHCHHHCC
GGRSIITTRSTAANDTISRIVPRLEGPVTTPRTDTHWIVTEFGSVNLKGLSSTERALRII
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHH
ELAHPNFRQQLRVDAKKMHLI
HHCCCCHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]