Click here to switch to the map view.

The map label for this gene is ldcA [H]

Identifier: 194734546

GI number: 194734546

Start: 1876805

End: 1877719

Strand: Direct

Name: ldcA [H]

Synonym: SeSA_A1942

Alternate gene names: 194734546

Gene position: 1876805-1877719 (Clockwise)

Preceding gene: 194738062

Following gene: 194735060

Centisome position: 39.86

GC content: 56.17

Gene sequence:

>915_bases
ATGTCTCTGTTTCATTTAATCGCCCCCTCGGGCTACTGTATTAACCAACAGGCCGCGTTACGCGGCGTTCAGCGCCTGAC
TGACGCGGGCCATCAGGTGGAGAATGACGAGGTGATTCGTCGCCGCTATCAGCGTTTTGCCGGTACGGACGCGGAACGGC
TGGCCGATGTTAATTCGCTGGCCTCGCTAACTTCGCCGGATACGATCGTCATGCCGGTTCGCGGCGGCTATGGCGCCAGC
CGCTTGCTGGATCGTATCGACTGGCAGGCGCTCGCCTCCCGGCAACAGCGCGATCCCTTACTGATTTGCGGTCATAGCGA
TTTTACGGCGATTCAGGCTGGACTCCTGGCGCAGGCCAATGTCATCACCTTTAGCGGTCCTATGCTGGCGGCAAATTTTG
GCGCCGAAACGCTGAATACGTTCACCGAGCAACATTTCTGGCTGGCGCTACGTAAGGCGCAATTTACCGTAGAGTGGCAA
GGCGACGGCCCTCAGTGCGACGTACAAGGCACCTTATGGGGCGGAAATCTGGCGATGTTGATTTCCCTTATCGATACGCC
CTGGATGCCGACTATCGATAAAGGAATTTTAGTGCTGGAAGATGTCAATGAGCATCCTTTCCGGGTGGAGCGTATGCTTT
TGCAACTGGAGTACGCCGGAATTTTAAACCGTCAGAGCGCCATCGTTCTCGGCAGCTTTAGCGGCGCGGCGCCCAACGAG
TATGACGCTGGCTATTCTCTGGAGAGCGTCTACGCGTTTTTACGTTCCCGTCTGTCCGTTCCGCTGATTACCGGTCTCGA
CTTCGGGCATGAACAGCGTACGGTGACGCTCCCTATCGGGGCAAACGCGACGCTTAAAAATACGCGCCAGGGGACTCAAC
TCACTTTATCTGGTCATCCTACGCTGCAATTGTAA

Upstream 100 bases:

>100_bases
CCTCCCTGGTGCGCATCCAGAAACGTCGCACAACGAGGGACATCGCCTAATATATGCGGCATGATATACATTTGCATTCT
ATTGTCAGCAAGGAATTACC

Downstream 100 bases:

>100_bases
AAAAAGTCCCCGACAGGCTAAGTAAAACGCTGCCCTGGCCGTTATTATGTTAATGTTAAATAATACGAAGTCGTGTGAGT
CAGGAGATATAAAACGTTGG

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQRFAGTDAERLADVNSLASLTSPDTIVMPVRGGYGAS
RLLDRIDWQALASRQQRDPLLICGHSDFTAIQAGLLAQANVITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQ
GDGPQCDVQGTLWGGNLAMLISLIDTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEYAGILNRQSAIVLGSFSGAAPNE
YDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVTLPIGANATLKNTRQGTQLTLSGHPTLQL

Sequences:

>Translated_304_residues
MSLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQRFAGTDAERLADVNSLASLTSPDTIVMPVRGGYGAS
RLLDRIDWQALASRQQRDPLLICGHSDFTAIQAGLLAQANVITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQ
GDGPQCDVQGTLWGGNLAMLISLIDTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEYAGILNRQSAIVLGSFSGAAPNE
YDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVTLPIGANATLKNTRQGTQLTLSGHPTLQL
>Mature_303_residues
SLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQRFAGTDAERLADVNSLASLTSPDTIVMPVRGGYGASR
LLDRIDWQALASRQQRDPLLICGHSDFTAIQAGLLAQANVITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQG
DGPQCDVQGTLWGGNLAMLISLIDTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEYAGILNRQSAIVLGSFSGAAPNEY
DAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVTLPIGANATLKNTRQGTQLTLSGHPTLQL

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=304, Percent_Identity=79.2763157894737, Blast_Score=512, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33423; Mature: 33292

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQRFAGTDAERLADVNSL
CCEEEEECCCCCEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
ASLTSPDTIVMPVRGGYGASRLLDRIDWQALASRQQRDPLLICGHSDFTAIQAGLLAQAN
HHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCC
VITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQGDGPQCDVQGTLWGGNLAML
EEEECCCEEEECCCHHHHHHHHHHHHHEEEEEEEEEEEECCCCCEEEEEEEEECCCHHHH
ISLIDTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEYAGILNRQSAIVLGSFSGAAPNE
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
YDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVTLPIGANATLKNTRQGTQLTLSGHP
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCC
TLQL
CCCC
>Mature Secondary Structure 
SLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQRFAGTDAERLADVNSL
CEEEEECCCCCEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
ASLTSPDTIVMPVRGGYGASRLLDRIDWQALASRQQRDPLLICGHSDFTAIQAGLLAQAN
HHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCC
VITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQGDGPQCDVQGTLWGGNLAML
EEEECCCEEEECCCHHHHHHHHHHHHHEEEEEEEEEEEECCCCCEEEEEEEEECCCHHHH
ISLIDTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEYAGILNRQSAIVLGSFSGAAPNE
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
YDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVTLPIGANATLKNTRQGTQLTLSGHP
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCC
TLQL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]