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The map label for this gene is cheA [H]

Identifier: 194734522

GI number: 194734522

Start: 1995065

End: 1997074

Strand: Reverse

Name: cheA [H]

Synonym: SeSA_A2077

Alternate gene names: 194734522

Gene position: 1997074-1995065 (Counterclockwise)

Preceding gene: 194737421

Following gene: 194734423

Centisome position: 42.41

GC content: 54.93

Gene sequence:

>2010_bases
ATGGATATTAGCGATTTTTATCAGACATTTTTTGATGAAGCTGACGAGCTGTTGGCTGATATGGAGCAGCATCTGCTGGA
TTTGGTGCCGGAATCCCCGGACGCTGAACAACTGAACGCCATTTTTCGCGCGGCGCACTCCATTAAAGGCGGCGCGGGCA
CATTCGGCTTCACTATTCTGCAGGAAACCACACATTTAATGGAAAACCTGCTGGATGAAGCCCGACGCGGTGAAATGCAG
CTCAATACCGACATTATCAACCTGTTTTTGGAAACGAAAGATATTATGCAGGAACAGCTCGACGCCTATAAAAACTCCGA
AGAGCCGGATGCCGCAAGCTTCGAATATATCTGCAATGCGCTACGCCAGTTGGCGCTGGAGGCGAAAGGCGAAACCACGC
CGGCGGTCGTAGAAACCGCGGCACTAAGCGCGGCGATCCAGGAAGAGAGCGTAGCCGAAACTGAATCGCCTCGTGACGAG
AGTAAACTGCGCATTGTACTTTCACGGTTGAAAGCCAATGAGGTCGATCTGCTTGAAGAAGAGTTGGGCAATCTGGCTAC
TCTGACGGATGTCGTTAAGGGAGCGGATTCACTGTCGGCAACTCTGGATGGCAGCGTCGCGGAAGATGACATTGTCGCGG
TGCTCTGTTTTGTCATCGAGGCCGATCAGATCGCTTTTGAAAAAGTAGTCGCCGCGCCCGTGGAAAAAGCGCAAGAGAAA
ACCGAGGTAACGCCGGTAGCGCCTCCGGCAGTCGTTGCGCCAGCCGCCAAAAGCGCGGCGCATGAACATCATGCGGGGCG
TGAAAAACCTGCGCGTGAACGCGAGTCCACCAGCATTCGCGTGGCGGTAGAGAAAGTAGATCAGCTCATAAACCTGGTCG
GCGAGTTAGTGATTACCCAGTCAATGTTGGCCCAGCGTTCTAATGAGCTGGACCCGGTAAACCACGGCGATCTCATTACC
AGTATGGGTCAGTTACAACGTAACGCCCGCGACTTACAAGAGTCGGTGATGTCGATTCGCATGATGCCTATGGAGTACGT
CTTCAGCCGTTTCCCGCGTCTGGTACGCGATTTAGCGGGTAAACTGGGCAAGCAGGTAGAGCTGACGCTGGTGGGGAGCT
CCACTGAACTTGATAAAAGCCTGATCGAACGCATTATCGACCCGCTGACGCACCTGGTGCGCAACAGTCTCGACCACGGG
ATTGAAATGCCGGAAAAACGCCTTGAGGCGGGGAAAAATGTTGTCGGCAATCTGATTCTTTCCGCAGAACATCAGGGCGG
GAATATTTGTATTGAAGTGACCGATGACGGCGCGGGGCTTAACCGTGAGCGTATCCTGGCGAAGGCCATGTCGCAGGGGA
TGGCGGTGAATGAAAACATGACCGACGATGAAGTAGGCATGTTGATCTTCGCGCCGGGATTCTCAACTGCGGAACAGGTC
ACGGATGTCTCCGGTCGCGGCGTTGGCATGGATGTGGTGAAACGTAACATTCAGGAGATGGGCGGTCACGTTGAGATCCA
GTCAAAACAAGGCTCCGGCACCACGATTCGTATTCTGCTGCCGCTGACGCTGGCCATCCTCGATGGGATGTCGGTTCGCG
TGGCGGGGGAAGTTTTTATCCTGCCGTTGAATGCGGTGATGGAGTCGCTGCAACCGCGTGAAGAGGATCTTCATCCGCTG
GCGGGCGGCGAACGGGTTCTGGAAGTTCGCGGCGAGTATTTGCCGCTGGTCGAATTGTGGAAAGTGTTTGACGTGGACGG
GGCGAAAACCGAAGCCACGCAGGGCATTGTTGTGATCCTGCAAAGCGCGGGACGCCGTTACGCGCTGCTGGTCGATCAGC
TCATCGGTCAGCACCAGGTGGTGGTCAAAAATCTGGAAAGCAATTATCGCAAGGTACCGGGGATTTCCGCCGCGACGATC
CTGGGCGACGGCAGCGTCGCGCTGATTGTTGATGTTTCCGCATTGCAGGGTTTAAACCGCGAACAACGTATGGCGATCAC
AGCCGCCTGA

Upstream 100 bases:

>100_bases
AGCCAGAATGAGCCGGTAAGTGTATTACAACAGCCTGCGGCAGCCCCGCCGGCAAGCGTACCCACATCGCCAAAAGCGGA
ACCGAGGTGATAGCGTGAGC

Downstream 100 bases:

>100_bases
TTGAGTGAGAAGGGAATAATATGACCGGTATGAGTAATGTAAGCAAACTGGCCGGCGAGCCGTCAGGTCAGGAATTCCTG
GTGTTTACACTGGGAAATGA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDE
SKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVAAPVEKAQEK
TEVTPVAPPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDLIT
SMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHG
IEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQV
TDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLHPL
AGGERVLEVRGEYLPLVELWKVFDVDGAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATI
LGDGSVALIVDVSALQGLNREQRMAITAA

Sequences:

>Translated_669_residues
MDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDE
SKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVAAPVEKAQEK
TEVTPVAPPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDLIT
SMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHG
IEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQV
TDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLHPL
AGGERVLEVRGEYLPLVELWKVFDVDGAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATI
LGDGSVALIVDVSALQGLNREQRMAITAA
>Mature_669_residues
MDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDE
SKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVAAPVEKAQEK
TEVTPVAPPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDLIT
SMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHG
IEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQV
TDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLHPL
AGGERVLEVRGEYLPLVELWKVFDVDGAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATI
LGDGSVALIVDVSALQGLNREQRMAITAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=670, Percent_Identity=84.7761194029851, Blast_Score=1127, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72826; Mature: 72826

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
QETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNA
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDESKLRIVLSRLKANEVDLLEE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
ELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVAAPVEKAQEK
HHCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVTPVAPPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQ
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SMLAQRSNELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIEMPEKRLEAGKNVVGNLIL
HCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHE
SAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQV
EEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHH
TDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFI
HCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEECEEEE
LPLNAVMESLQPREEDLHPLAGGERVLEVRGEYLPLVELWKVFDVDGAKTEATQGIVVIL
EEHHHHHHHCCCCHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCHHCCCCEEEE
QSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQGLNR
ECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHCCCH
EQRMAITAA
HHCEEEECC
>Mature Secondary Structure
MDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
QETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNA
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDESKLRIVLSRLKANEVDLLEE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
ELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVAAPVEKAQEK
HHCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVTPVAPPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQ
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SMLAQRSNELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIEMPEKRLEAGKNVVGNLIL
HCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHE
SAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQV
EEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHH
TDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFI
HCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEECEEEE
LPLNAVMESLQPREEDLHPLAGGERVLEVRGEYLPLVELWKVFDVDGAKTEATQGIVVIL
EEHHHHHHHCCCCHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCHHCCCCEEEE
QSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQGLNR
ECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHCCCH
EQRMAITAA
HHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]