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The map label for this gene is ail [H]

Identifier: 194734078

GI number: 194734078

Start: 403173

End: 403697

Strand: Direct

Name: ail [H]

Synonym: SeSA_A0399

Alternate gene names: 194734078

Gene position: 403173-403697 (Clockwise)

Preceding gene: 194735944

Following gene: 194737661

Centisome position: 8.56

GC content: 41.71

Gene sequence:

>525_bases
ATGAAAAGACGGTCTTCGTTCCTTGTTTTTTTAGGTTTATTATTAGCGTCACCTTTAGCTTTGGCTAACGATCAGCACAC
CGTATCGTTTGGTTATGCACAAACTCATCTCAGTTCATTGAAAAATAGCGATAGCAAAGATCTGCGAGGCTTTAATTTTA
AATATCGTTACGAGTTCAATGAGACCTGGGGGATGTTAGGCTCATTCACCGCGACGCGCAATGAAATGGAGAACTACACC
TGGAAAGAGGGGAAGTTGCATAAAAATGGTTCCGATTCTGTGGACTATGGTTCTTTGATGTTTGGACCAACATATCGTTT
TAATGACTATGTGAGCCTGTACGGCAATGCGGGTATAGCGACGATGAAATTTAATAAACACTCAAAAGAAGACTCCTTTG
CCTACGGCGCTGGCGTAATATTTAATCCAGTTAAGAGTATATCTATCGATGCATCATGGGAAGCCAGTCGTTTCTTCGCT
GTGGATACCAATACATTTGGTGTCAGCGTAGGTTATCGCTTCTGA

Upstream 100 bases:

>100_bases
ACTGGTAATAAGCGCATTAGGTACTCTTAATCTAAATGCTATTTGTGTGCCATAAGTTCCGGTACCGCCTTAATTATATA
TCAAAAATGGAGTGGTTTTA

Downstream 100 bases:

>100_bases
TATTAAAAGTATAAGCGTTACGTTTATGGCAAGGAATTAAAAATAATATGGCGCTGCTACAGAATAGGGATGGTTATGAT
CGCTCAGGTAATCTTAAGAG

Product: attachment invasion locus protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSDSKDLRGFNFKYRYEFNETWGMLGSFTATRNEMENYT
WKEGKLHKNGSDSVDYGSLMFGPTYRFNDYVSLYGNAGIATMKFNKHSKEDSFAYGAGVIFNPVKSISIDASWEASRFFA
VDTNTFGVSVGYRF

Sequences:

>Translated_174_residues
MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSDSKDLRGFNFKYRYEFNETWGMLGSFTATRNEMENYT
WKEGKLHKNGSDSVDYGSLMFGPTYRFNDYVSLYGNAGIATMKFNKHSKEDSFAYGAGVIFNPVKSISIDASWEASRFFA
VDTNTFGVSVGYRF
>Mature_174_residues
MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSDSKDLRGFNFKYRYEFNETWGMLGSFTATRNEMENYT
WKEGKLHKNGSDSVDYGSLMFGPTYRFNDYVSLYGNAGIATMKFNKHSKEDSFAYGAGVIFNPVKSISIDASWEASRFFA
VDTNTFGVSVGYRF

Specific function: Promotes the invasion of pathogenic bacteria into eukaryotic cells by an unknown mechanism [H]

COG id: COG3637

COG function: function code M; Opacity protein and related surface antigens

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family [H]

Homologues:

Organism=Escherichia coli, GI1787034, Length=183, Percent_Identity=36.0655737704918, Blast_Score=97, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000758
- InterPro:   IPR011250 [H]

Pfam domain/function: PF06316 Ail_Lom [H]

EC number: NA

Molecular weight: Translated: 19674; Mature: 19674

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSDSKDLRGFNFKYRYEFN
CCCCHHHHHHHHHHHHCCHHCCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
ETWGMLGSFTATRNEMENYTWKEGKLHKNGSDSVDYGSLMFGPTYRFNDYVSLYGNAGIA
CCCCCHHCCHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCEEEEECCCCEE
TMKFNKHSKEDSFAYGAGVIFNPVKSISIDASWEASRFFAVDTNTFGVSVGYRF
EEEECCCCCCCCEEECCCEEECCCCEEEECCCCCCCEEEEEECCCEEEEEEECC
>Mature Secondary Structure
MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSDSKDLRGFNFKYRYEFN
CCCCHHHHHHHHHHHHCCHHCCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
ETWGMLGSFTATRNEMENYTWKEGKLHKNGSDSVDYGSLMFGPTYRFNDYVSLYGNAGIA
CCCCCHHCCHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCEEEEECCCCEE
TMKFNKHSKEDSFAYGAGVIFNPVKSISIDASWEASRFFAVDTNTFGVSVGYRF
EEEECCCCCCCCEEECCCEEECCCCEEEECCCCCCCEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1688838 [H]