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The map label for this gene is spaN [H]

Identifier: 194734072

GI number: 194734072

Start: 2942442

End: 2943452

Strand: Reverse

Name: spaN [H]

Synonym: SeSA_A3045

Alternate gene names: 194734072

Gene position: 2943452-2942442 (Counterclockwise)

Preceding gene: 194734552

Following gene: 194738216

Centisome position: 62.51

GC content: 48.37

Gene sequence:

>1011_bases
ATGGGCGATGTGTCAGCTGTCAGTTCATCCGGGAACATTTTACTGCCGCAGCAGGATGAGGTTGGCGGTTTATCAGAAGC
ATTAAAAAAAGCGGTGGAAAAACATAAGACAGAATATTCCGATCATAAAAAAGATCGCGACTATGGCGATGCTTTCGTAA
TGCATAAAGAAACGGCTTTACCGGTATTGCTGGCGGCATGGCGACATGGCGCGCTAGCGAAATCAGAACATCACAATGGC
AACGTTTCTGGTCTGCATCATAACGGAAAAGGCGAACTCAGGATTGCTGAAAAACTGTTGAAAGTCACTGCTGAAAAATC
TGTCGGTTTGATCTCTGCGGAGGCCAAAGTAGATAAATCCGCAGCGTTGCTATCGTCTAAAAATAGGCCGTTAGAAAGCG
TAAGTGGTAAAAAATTATCTGCTGATTTAAAAGCTGTGGAATCCGTTAGTGAAGTAACCGATAACGCCACGGGAATCTCT
GACGATAATATCAAGGCATTGCCTGGGGATAATAAAGCCATCGCGGGTGAAGGCGTTCGTAAAGAGGGCGCGCCGCTGGC
GCGGGATGTCGCATCTGCCCGAATGGCCGCAGCCAATACCGGTAAGCCTGACGATAAAGATCATAAAAAGGTTAAAGATG
TTTCTCAGCTTCCGCTGCAACCAACCACTATCGCCGATCTTAGCCAATTAACCGGCGGCGATGAAAAAATGCCTTTAGCG
GCGCAATCAAAGCCGATGATGACTATTTTTCCCACTGCCGATGGCGTGAAAGGGGAGGATAGCTCACTGACTTACCGTTT
TCAGCGCTGGGGAAATGACTATTCCGTCAATATTCAGGCGCGGCAAGCAGGGGAGTTTTCGTTAATACCGTCAAATACGC
AGGTTGAACATCGTTTGCATGATCAATGGCAAAACGGTAATCCCCAGCGCTGGCACCTGACGCGAGACGATCAACAAAAT
CCGCAGCAGCAACAGCACAGACAGCAATCTGGCGAGGAGGATGACGCCTGA

Upstream 100 bases:

>100_bases
GCAAAGAAGGGAACTATCAACGCTGGATAATCCGTCAGAAAAGACACTATATCCAGCGAGAGATACAGCAGGAAGAGGCC
GAGTCAGAGGAGATAATTTA

Downstream 100 bases:

>100_bases
TGTCATTGCGTGTGAGACAGATTGATCGTCGCGAATGGCTATTGGCGCAAACCGCGACAGAATGCCAGCGCCATGGCCAG
GAAGCTACGCTGGAATATCC

Product: antigen presentation protein SpaN

Products: NA

Alternate protein names: Invasion protein invJ [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSDHKKDRDYGDAFVMHKETALPVLLAAWRHGALAKSEHHNG
NVSGLHHNGKGELRIAEKLLKVTAEKSVGLISAEAKVDKSAALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGIS
DDNIKALPGDNKAIAGEGVRKEGAPLARDVASARMAAANTGKPDDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA
AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLHDQWQNGNPQRWHLTRDDQQN
PQQQQHRQQSGEEDDA

Sequences:

>Translated_336_residues
MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSDHKKDRDYGDAFVMHKETALPVLLAAWRHGALAKSEHHNG
NVSGLHHNGKGELRIAEKLLKVTAEKSVGLISAEAKVDKSAALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGIS
DDNIKALPGDNKAIAGEGVRKEGAPLARDVASARMAAANTGKPDDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA
AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLHDQWQNGNPQRWHLTRDDQQN
PQQQQHRQQSGEEDDA
>Mature_335_residues
GDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSDHKKDRDYGDAFVMHKETALPVLLAAWRHGALAKSEHHNGN
VSGLHHNGKGELRIAEKLLKVTAEKSVGLISAEAKVDKSAALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGISD
DNIKALPGDNKAIAGEGVRKEGAPLARDVASARMAAANTGKPDDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLAA
QSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLHDQWQNGNPQRWHLTRDDQQNP
QQQQHRQQSGEEDDA

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spaN family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003066
- ProDom:   PD004696 [H]

Pfam domain/function: PF02510 SPAN [H]

EC number: NA

Molecular weight: Translated: 36466; Mature: 36335

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSDHKKDRDYGDAFVMHKETAL
CCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
PVLLAAWRHGALAKSEHHNGNVSGLHHNGKGELRIAEKLLKVTAEKSVGLISAEAKVDKS
HHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCHHCHH
AALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGISDDNIKALPGDNKAIAGEGVR
HHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEECCCCCC
KEGAPLARDVASARMAAANTGKPDDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLH
CCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCEEECCCCCHHHHHHH
DQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEEDDA
HHHCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSDHKKDRDYGDAFVMHKETAL
CCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
PVLLAAWRHGALAKSEHHNGNVSGLHHNGKGELRIAEKLLKVTAEKSVGLISAEAKVDKS
HHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCHHCHH
AALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGISDDNIKALPGDNKAIAGEGVR
HHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEECCCCCC
KEGAPLARDVASARMAAANTGKPDDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLH
CCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCEEECCCCCHHHHHHH
DQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEEDDA
HHHCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8404849; 7752894; 11677609 [H]