Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 194334659

GI number: 194334659

Start: 2033760

End: 2035898

Strand: Reverse

Name: recG [H]

Synonym: Paes_1860

Alternate gene names: 194334659

Gene position: 2035898-2033760 (Counterclockwise)

Preceding gene: 194334662

Following gene: 194334658

Centisome position: 81.02

GC content: 52.73

Gene sequence:

>2139_bases
ATGTCTATGTTGAGAATGAATAGTGACTCAACTCCTCTGACCTTTGTCAAAGGAGTTGGCCCGGAGAAAGCCAGGGTGCT
TGAAGCCGAAGGGCTCGGGAGCGTCCGGGATCTCTACGAGTATTTTCCCAGACGTTACCTCGACAGGAGCAGGCTGAAAT
CGATAGGTTCTCTTGCCGAGGGTGAACTTGTGACGGTTGTCGGAACGGTATCGCGGGCAGAAAAAGAGCGTTCTTCATCC
GGAAAGGCTCTTTTCAGGGTCTGGCTATCGGACGGGACCGGTAATCTTGTGCTGACCTGGTTCCGGGGGGCGGTCTATTT
TTCGAAAATGGTTCGTCCGGGCGACCTTCTGGCAGTGCATGGCAAGGTTGGTTTTTTTTGTGGCCATGCCCAGATGCAGC
ATCCTGATTTTGACCGTTTACAGGACGCTTCGGCAGAAAGCGGAGCCAAAGGGGTGAGCGATGCAGATCTTTTCCATACA
GGCGGGATTATCCCGCTCTATCCGGTAACGGATGCCATGAAAAAAGCGGGGCTGGATTCCCGGCGTCTGCGTGCGATTAT
ACTCCGCGCAATGGAAAGCCATCCTGCCTTCATAGACGAACATCTTCCGGACAGCATCATTGCCTCTCACGGTTTGCTGG
AGATCAATCTGGCATATCGTCAGATTCATTGTCCTGTTTCCTCCGAAATGCTTGAGCGGGCTGTCCACCGTTTTAAATGG
AATGAGCTCTTTTACGCCCAGCTCTTTTTCGCTCTTCGCTATCACGCGCAGAAAAAGAATAATGCAGCGGTGCGTTTCGA
GCGTTCCGGGGACAAAACAGCGCTTTTGTACTCCCTGCTGCCATTCAGTATGACAGATGCTCAGAAACAGGCGGTTCGCG
AGATTTATCGAGACCTGAGAAGCGGCTCCCAGATGAACAGACTGCTTCAGGGTGATGTGGGGTCGGGTAAAACCCTTGTT
GCCATGTTTTCGATGGCACTTGCAGTCGATAACGGCCTTCAGGCTGCCATCATGGCGCCGACCGAAATTCTGGCTTTCCA
GCACTGGCTCGGTATCCGGAAATATTGCGAACCGCTCGGCCTGCGTGTCGGTCTCCTTACCGGCAGCCAGAAAAAAAAGG
AGAGGGACGTCATATTGAGCGGCCTTGAGGATGGTTCATATGATCTCGCTGTCGGAACGCATGCCATGATCGAGGAGCGG
GTGCGGTTTAAAAGGCTCGGCCTGATTATTATCGATGAACAGCACCGGTTCGGTGTTCTGCAACGCAAGGCGCTTCAGGA
TAAATCCGTGAATCCTCATGTGCTGCTGATGACGGCGACACCCATACCCAGAACGCTCTGTATGGGGGCGTTTGGTGATC
TTGACGTGACGCTGATCGATGAGTTGCCGGGGGGCAGAAAAGCGATCGTTACCCGTCTGTGCCACGAAAACAGCAAGCCA
CGGGTTTTAGAGCTGATCCGAAAAGAGGTTGCGGCGGGCCGGCAGGCATATATTGTCTATCCGCTTGTCGATGAATCTGA
AAAAATCGATCTTAAAGCTGCTACGGACAGTTATCTGCAGTTGCAAAAGGATCTTTTGCCTGAATTAAGGATCGGTCTGG
TTCACGGCCGGATGAAGCCTGCCGAAAAAGAGCTCATCATGGACCGGTTCAGGCAGGGAGATGTCGATGTGCTTGTCGGG
ACAACGGTTATAGAGGTGGGGGTTGATGTTCCCAATGCCACAGTCATGGTCATCGAGCATGCTGAGCGTTTTGGTCTTGC
ACAGCTGCATCAGCTCAGGGGGCGTGTCGGCAGGGGGCCTGAGCAGTCCTATTGCTATTTACTCTACTCCCGTCTTGGTG
GTGATGCCGCAGAGCGGTTACGGGCGATGGAGGCGTCGACAGATGGGTTCAGGTTGTCGGAGATTGACGCCCGGATCCGT
GGAACGGGCAATGTTCTGGGAAAGGAGCAGTCCGGTATGGTTTCAGGTTTTTCGATGGCGGATCTGAACCGTGATTCGGA
GATTCTTGACGTTGCACGAGATGCGGCGTTTCGTCTTGTCGATGATGATCCTCAGCTTCGAAATCCTCTGCATCGCGGTA
TTCGAAATTATTATACAACGCATTATCATGAAAAATTTTCTCTTGCCGATATTGGCTGA

Upstream 100 bases:

>100_bases
AATATACAAGTTTTAAAACGCAGATACAAACCTGTGATTCCCTCTCACGGGAAGTTTTGCATTGCCTGAATGGAAGGGAG
CGGTGTGCGTCGAGGCCGAT

Downstream 100 bases:

>100_bases
AGAGATCGCTCGGGGTGGCCTGCTATGAGCATGTCGCCGGAAGTGATGGAGATTGAGGGCTTTGTTACCGAAGCCAGGGG
GGGGATGTATATTGTTCGCG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSMLRMNSDSTPLTFVKGVGPEKARVLEAEGLGSVRDLYEYFPRRYLDRSRLKSIGSLAEGELVTVVGTVSRAEKERSSS
GKALFRVWLSDGTGNLVLTWFRGAVYFSKMVRPGDLLAVHGKVGFFCGHAQMQHPDFDRLQDASAESGAKGVSDADLFHT
GGIIPLYPVTDAMKKAGLDSRRLRAIILRAMESHPAFIDEHLPDSIIASHGLLEINLAYRQIHCPVSSEMLERAVHRFKW
NELFYAQLFFALRYHAQKKNNAAVRFERSGDKTALLYSLLPFSMTDAQKQAVREIYRDLRSGSQMNRLLQGDVGSGKTLV
AMFSMALAVDNGLQAAIMAPTEILAFQHWLGIRKYCEPLGLRVGLLTGSQKKKERDVILSGLEDGSYDLAVGTHAMIEER
VRFKRLGLIIIDEQHRFGVLQRKALQDKSVNPHVLLMTATPIPRTLCMGAFGDLDVTLIDELPGGRKAIVTRLCHENSKP
RVLELIRKEVAAGRQAYIVYPLVDESEKIDLKAATDSYLQLQKDLLPELRIGLVHGRMKPAEKELIMDRFRQGDVDVLVG
TTVIEVGVDVPNATVMVIEHAERFGLAQLHQLRGRVGRGPEQSYCYLLYSRLGGDAAERLRAMEASTDGFRLSEIDARIR
GTGNVLGKEQSGMVSGFSMADLNRDSEILDVARDAAFRLVDDDPQLRNPLHRGIRNYYTTHYHEKFSLADIG

Sequences:

>Translated_712_residues
MSMLRMNSDSTPLTFVKGVGPEKARVLEAEGLGSVRDLYEYFPRRYLDRSRLKSIGSLAEGELVTVVGTVSRAEKERSSS
GKALFRVWLSDGTGNLVLTWFRGAVYFSKMVRPGDLLAVHGKVGFFCGHAQMQHPDFDRLQDASAESGAKGVSDADLFHT
GGIIPLYPVTDAMKKAGLDSRRLRAIILRAMESHPAFIDEHLPDSIIASHGLLEINLAYRQIHCPVSSEMLERAVHRFKW
NELFYAQLFFALRYHAQKKNNAAVRFERSGDKTALLYSLLPFSMTDAQKQAVREIYRDLRSGSQMNRLLQGDVGSGKTLV
AMFSMALAVDNGLQAAIMAPTEILAFQHWLGIRKYCEPLGLRVGLLTGSQKKKERDVILSGLEDGSYDLAVGTHAMIEER
VRFKRLGLIIIDEQHRFGVLQRKALQDKSVNPHVLLMTATPIPRTLCMGAFGDLDVTLIDELPGGRKAIVTRLCHENSKP
RVLELIRKEVAAGRQAYIVYPLVDESEKIDLKAATDSYLQLQKDLLPELRIGLVHGRMKPAEKELIMDRFRQGDVDVLVG
TTVIEVGVDVPNATVMVIEHAERFGLAQLHQLRGRVGRGPEQSYCYLLYSRLGGDAAERLRAMEASTDGFRLSEIDARIR
GTGNVLGKEQSGMVSGFSMADLNRDSEILDVARDAAFRLVDDDPQLRNPLHRGIRNYYTTHYHEKFSLADIG
>Mature_711_residues
SMLRMNSDSTPLTFVKGVGPEKARVLEAEGLGSVRDLYEYFPRRYLDRSRLKSIGSLAEGELVTVVGTVSRAEKERSSSG
KALFRVWLSDGTGNLVLTWFRGAVYFSKMVRPGDLLAVHGKVGFFCGHAQMQHPDFDRLQDASAESGAKGVSDADLFHTG
GIIPLYPVTDAMKKAGLDSRRLRAIILRAMESHPAFIDEHLPDSIIASHGLLEINLAYRQIHCPVSSEMLERAVHRFKWN
ELFYAQLFFALRYHAQKKNNAAVRFERSGDKTALLYSLLPFSMTDAQKQAVREIYRDLRSGSQMNRLLQGDVGSGKTLVA
MFSMALAVDNGLQAAIMAPTEILAFQHWLGIRKYCEPLGLRVGLLTGSQKKKERDVILSGLEDGSYDLAVGTHAMIEERV
RFKRLGLIIIDEQHRFGVLQRKALQDKSVNPHVLLMTATPIPRTLCMGAFGDLDVTLIDELPGGRKAIVTRLCHENSKPR
VLELIRKEVAAGRQAYIVYPLVDESEKIDLKAATDSYLQLQKDLLPELRIGLVHGRMKPAEKELIMDRFRQGDVDVLVGT
TVIEVGVDVPNATVMVIEHAERFGLAQLHQLRGRVGRGPEQSYCYLLYSRLGGDAAERLRAMEASTDGFRLSEIDARIRG
TGNVLGKEQSGMVSGFSMADLNRDSEILDVARDAAFRLVDDDPQLRNPLHRGIRNYYTTHYHEKFSLADIG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=691, Percent_Identity=40.520984081042, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1787357, Length=432, Percent_Identity=38.6574074074074, Blast_Score=274, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79467; Mature: 79335

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMLRMNSDSTPLTFVKGVGPEKARVLEAEGLGSVRDLYEYFPRRYLDRSRLKSIGSLAE
CCCEECCCCCCCEEEEECCCCCHHEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCC
GELVTVVGTVSRAEKERSSSGKALFRVWLSDGTGNLVLTWFRGAVYFSKMVRPGDLLAVH
CCEEEEEEHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCEEEEE
GKVGFFCGHAQMQHPDFDRLQDASAESGAKGVSDADLFHTGGIIPLYPVTDAMKKAGLDS
CCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCEEEECCCHHHHHHCCCCH
RRLRAIILRAMESHPAFIDEHLPDSIIASHGLLEINLAYRQIHCPVSSEMLERAVHRFKW
HHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHH
NELFYAQLFFALRYHAQKKNNAAVRFERSGDKTALLYSLLPFSMTDAQKQAVREIYRDLR
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHH
SGSQMNRLLQGDVGSGKTLVAMFSMALAVDNGLQAAIMAPTEILAFQHWLGIRKYCEPLG
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHC
LRVGLLTGSQKKKERDVILSGLEDGSYDLAVGTHAMIEERVRFKRLGLIIIDEQHRFGVL
CEEEEECCCCCHHHHHHHEECCCCCCEEEEECHHHHHHHHHHHHHCCEEEEECCHHHHHH
QRKALQDKSVNPHVLLMTATPIPRTLCMGAFGDLDVTLIDELPGGRKAIVTRLCHENSKP
HHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCH
RVLELIRKEVAAGRQAYIVYPLVDESEKIDLKAATDSYLQLQKDLLPELRIGLVHGRMKP
HHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCC
AEKELIMDRFRQGDVDVLVGTTVIEVGVDVPNATVMVIEHAERFGLAQLHQLRGRVGRGP
HHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCC
EQSYCYLLYSRLGGDAAERLRAMEASTDGFRLSEIDARIRGTGNVLGKEQSGMVSGFSMA
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHH
DLNRDSEILDVARDAAFRLVDDDPQLRNPLHRGIRNYYTTHYHEKFSLADIG
CCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCEEECCCCC
>Mature Secondary Structure 
SMLRMNSDSTPLTFVKGVGPEKARVLEAEGLGSVRDLYEYFPRRYLDRSRLKSIGSLAE
CCEECCCCCCCEEEEECCCCCHHEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCC
GELVTVVGTVSRAEKERSSSGKALFRVWLSDGTGNLVLTWFRGAVYFSKMVRPGDLLAVH
CCEEEEEEHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCEEEEE
GKVGFFCGHAQMQHPDFDRLQDASAESGAKGVSDADLFHTGGIIPLYPVTDAMKKAGLDS
CCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCEEEECCCHHHHHHCCCCH
RRLRAIILRAMESHPAFIDEHLPDSIIASHGLLEINLAYRQIHCPVSSEMLERAVHRFKW
HHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHH
NELFYAQLFFALRYHAQKKNNAAVRFERSGDKTALLYSLLPFSMTDAQKQAVREIYRDLR
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHH
SGSQMNRLLQGDVGSGKTLVAMFSMALAVDNGLQAAIMAPTEILAFQHWLGIRKYCEPLG
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHC
LRVGLLTGSQKKKERDVILSGLEDGSYDLAVGTHAMIEERVRFKRLGLIIIDEQHRFGVL
CEEEEECCCCCHHHHHHHEECCCCCCEEEEECHHHHHHHHHHHHHCCEEEEECCHHHHHH
QRKALQDKSVNPHVLLMTATPIPRTLCMGAFGDLDVTLIDELPGGRKAIVTRLCHENSKP
HHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCH
RVLELIRKEVAAGRQAYIVYPLVDESEKIDLKAATDSYLQLQKDLLPELRIGLVHGRMKP
HHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCC
AEKELIMDRFRQGDVDVLVGTTVIEVGVDVPNATVMVIEHAERFGLAQLHQLRGRVGRGP
HHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCC
EQSYCYLLYSRLGGDAAERLRAMEASTDGFRLSEIDARIRGTGNVLGKEQSGMVSGFSMA
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCHH
DLNRDSEILDVARDAAFRLVDDDPQLRNPLHRGIRNYYTTHYHEKFSLADIG
CCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]